Shilpa Kadam

A methylation-mediator complex in hormone signaling (2004)

Xu, Wei, Cho, Helen, Kadam, Shilpa, Banayo, Ester M., Anderson, Scott, Yates, John R., ...

The recruitment of coactivators by nuclear hormone receptors (NRs) promotes transcription by subverting chromatin-mediated repression. Although the histone methylation enzyme CARM1 and an...

A methylation-mediator complex in hormone signaling (2004)

Xu, Wei, Cho, Helen, Kadam, Shilpa, Banayo, Ester M., Anderson, Scott, Yates, John R., ...

The recruitment of coactivators by nuclear hormone receptors (NRs) promotes transcription by subverting chromatin-mediated repression. Although the histone methylation enzyme CARM1 and an...

A methylation-mediator complex in hormone signaling (2004)

Xu, Wei, Cho, Helen, Kadam, Shilpa, Banayo, Ester M., Anderson, Scott, Yates, John R., ...

The recruitment of coactivators by nuclear hormone receptors (NRs) promotes transcription by subverting chromatin-mediated repression. Although the histone methylation enzyme CARM1 and an...

Site-Specific Acetylation by p300 or CREB Binding Protein Regulates Erythroid Krüppel-Like Factor Transcriptional Activity via Its Interaction with the SWI-SNF Complex

Zhang, Wenjun, Kadam, Shilpa, Emerson, Beverly M., Bieker, James J.

Recruitment of modifiers and remodelers to specific DNA sites within chromatin plays a critical role in controlling gene expression. The study of globin gene regulation provides a convergence point...

Functional selectivity of recombinant mammalian SWI/SNF subunits

Kadam, Shilpa, McAlpine, Glenn S., Phelan, Michael L., Kingston, Robert E., Jones, Katherine A., Emerson, Beverly M.

The SWI/SNF family of chromatin-remodeling complexes plays a key role in facilitating the binding of specific transcription factors to nucleosomal DNA in diverse organisms from yeast to man. Yet the...

A methylation-mediator complex in hormone signaling

Xu, Wei, Cho, Helen, Kadam, Shilpa, Banayo, Ester M., Anderson, Scott, Yates, John R., ...

The recruitment of coactivators by nuclear hormone receptors (NRs) promotes transcription by subverting chromatin-mediated repression. Although the histone methylation enzyme CARM1 and an...

Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

Zhang, Xinmin, Odom, Duncan T., Koo, Seung-Hoi, Conkright, Michael D., Canettieri, Gianluca, Best, Jennifer, ...

Hormones and nutrients often induce genetic programs via signaling pathways that interface with gene-specific activators. Activation of the cAMP pathway, for example, stimulates cellular gene...

Site-Specific Acetylation by p300 or CREB Binding Protein Regulates Erythroid Krüppel-Like Factor Transcriptional Activity via Its Interaction with the SWI-SNF Complex

Zhang, Wenjun, Kadam, Shilpa, Emerson, Beverly M., Bieker, James J.

Recruitment of modifiers and remodelers to specific DNA sites within chromatin plays a critical role in controlling gene expression. The study of globin gene regulation provides a convergence point...

Functional selectivity of recombinant mammalian SWI/SNF subunits

Kadam, Shilpa, McAlpine, Glenn S., Phelan, Michael L., Kingston, Robert E., Jones, Katherine A., Emerson, Beverly M.

The SWI/SNF family of chromatin-remodeling complexes plays a key role in facilitating the binding of specific transcription factors to nucleosomal DNA in diverse organisms from yeast to man. Yet the...

A methylation-mediator complex in hormone signaling

Xu, Wei, Cho, Helen, Kadam, Shilpa, Banayo, Ester M., Anderson, Scott, Yates, John R., ...

The recruitment of coactivators by nuclear hormone receptors (NRs) promotes transcription by subverting chromatin-mediated repression. Although the histone methylation enzyme CARM1 and an...

Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

Zhang, Xinmin, Odom, Duncan T., Koo, Seung-Hoi, Conkright, Michael D., Canettieri, Gianluca, Best, Jennifer, ...

Hormones and nutrients often induce genetic programs via signaling pathways that interface with gene-specific activators. Activation of the cAMP pathway, for example, stimulates cellular gene...

The Histone H3K79 Methyltransferase Dot1L Is Essential for Mammalian Development and Heterochromatin Structure

Jones, Brendan, Su, Hui, Bhat, Audesh, Lei, Hong, Bajko, Jeffrey, Hevi, Sarah, ...

Dot1 is an evolutionarily conserved histone methyltransferase specific for lysine 79 of histone H3 (H3K79). In Saccharomyces cerevisiae, Dot1-mediated H3K79 methylation is associated with telomere...