Tapchaisri, Pramuan, Na-Ubol, Mathukorn, Tiyasuttipan, Watcharee, Chaiyaroj, Sansanee C., Yamasaki, Shinji, Wongsaroj, Thitima, ...
The aim of the present study was to genotypically characterize Vibrio cholerae strains isolated from cholera patients in various provinces of Thailand. Two hundred and forty V. cholerae O1...
Kazuhiko Nishimura, Michiko Yagi, Yoshihiro Ohnishi, Shinji Yamasaki
Feeding polyamine-deficient chow (PDC) to rats decreases blood polyamines, increases the activity of ornithine decarboxylase as an index of polyamine production, and increases resistance to...
Inhibition of Interleukin-12 Production by Trypanosoma brucei in Rat Macrophages (2008)
Kazuhiko Nishimura, Shinsuke Sakakibara, Kousuke Mitani, Jyoji Yamate, Yoshihiro Ohnishi, Shinji Yamasaki
The immune response of a host infected with Trypanosoma brucei is modulated by trypomastigotes. We examined the changes in cytokine production in T. brucei gambiense (Wellcome strain; WS) infected...
Kazuhiko Nishimura, Takako Yanase, Noriko Araki, Yoshihiro Ohnishi, Shunji Kozaki, Kensuke Shima, ...
Effects of Heparin Administration on Trypanosoma brucei gambiense Infection in Rats (2005)
Kazuhiko Nishimura, Kensuke Shima, Masahiro Asakura, Yoshihiro Ohnishi, Shinji Yamasaki
We examined whether heparin administration influences in vivo trypanosome proliferation in infected rats. Administration of heparin every 8 hr via cardiac catheter inhibited growth of Trypanosoma...
Kazuhiko Nishimura, Kanako Hamashita, Yasuyuki Okamoto, Fumiya Kawahara, Hideshi Ihara, Shunji Kozaki, ...
Trypanosome-derived lymphocyte-triggering factor (TLTF) produced by Trypanosoma brucei brucei stimulates production of interferon-γ (IFN-γ) by CD8+ T cells, and it is reported that, in turn, IFN-γ...
Bag, Prasanta K., Nandi, Suvobroto, Bhadra, Rupak K., Ramamurthy, T., Bhattacharya, S. K., Nishibuchi, M., ...
The genomes of the O3:K6 strains of Vibrio parahaemolyticus which abruptly emerged in Calcutta, India, in February 1996 and which demonstrated an unusual potential to spread and an enhanced...
Garg, Pallavi, Nandy, Ranjan K., Chaudhury, Papiya, Chowdhury, Nandini Roy, De, Keya, Ramamurthy, T., ...
The toxigenic Inaba serotype of Vibrio cholerae O1 biotype El Tor reappeared in India in 1998 and 1999, almost 10 years after its last dominance in Calcutta in 1989. Extensive molecular...
Virulence Genes in Environmental Strains of Vibrio cholerae
Chakraborty, Soumen, Mukhopadhyay, Asish K., Bhadra, Rupak Kumar, Ghosh, Amar Nath, Mitra, Rupak, Shimada, Toshio, ...
The virulence of a pathogen is dependent on a discrete set of genetic determinants and their well-regulated expression. The ctxAB and tcpA genes are known to play a cardinal role in maintaining...
Monoclonal Antibody to Shiga Toxin 2 Which Blocks Receptor Binding and Neutralizes Cytotoxicity
Nakao, Hiroshi, Kiyokawa, Nobutaka, Fujimoto, Junichiro, Yamasaki, Shinji, Takeda, Tae
A monoclonal antibody (MAb) was raised against Shiga toxin 2 (Stx2) of Escherichia coli O157:H7. MAb VTm1.1 belonged to the immunoglobulin G1 subclass and had a κ light chain, and it could...
Ogawa, Michinaga, Shimizu, Kensuke, Nomoto, Koji, Takahashi, Masatoshi, Watanuki, Masaaki, Tanaka, Ryuichiro, ...
We examined colonization patterns of Shiga toxin-producing Escherichia coli (STEC), concentrations of Shiga toxins (Stxs) and specific immunoglobulin A (lgA) against Stxs and STEC bacterial cell...
Watarai, Masahisa, Sato, Toshio, Kobayashi, Midori, Shimizu, Takeshi, Yamasaki, Shinji, Tobe, Toru, ...
Shiga toxins 1 (Stx1) and 2 (Stx2) are encoded by toxin-converting bacteriophages of Stx-producing Escherichia coli (STEC), and so far two Stx1- and one Stx2-converting phages have been isolated from...
Faruque, Shah M., Khan, Rasel, Kamruzzaman, M., Yamasaki, Shinji, Ahmad, Q. Shafi, Azim, Tasnim, ...
Bacillary dysentery caused by Shigella species is a public health problem in developing countries including Bangladesh. Although, shigellae-contaminated food and drinks are often the source of the...
Karasawa, Tadahiro, Ito, Hideaki, Tsukamoto, Teizo, Yamasaki, Shinji, Kurazono, Hisao, Faruque, Shah M., ...
We identified and characterized a gene encoding a homologue of the B subunits of cholera toxin (CTB) and heat-labile enterotoxin (LTB) of Escherichia coli from a clinical isolate of Citrobacter...
Sato, Toshio, Shimizu, Takeshi, Watarai, Masahisa, Kobayashi, Midori, Kano, Shigeyuki, Hamabata, Takashi, ...
Two Stx-converting phages, designated Stx1φ and Stx2φ-II, were isolated from an Escherichia coli O157:H7 strain, Morioka V526, and their entire nucleotide sequences were determined. The genomes of...
Pandey, Mritunjay, Khan, Asis, Das, Suresh C., Sarkar, Bhaswati, Kahali, Soumen, Chakraborty, Subhra, ...
Among Escherichia coli strains isolated from stool specimens from patients with acute diarrhea, 1.4% were found to harbor cdtB by use of enrichment cytolethal distending toxin (CDT) PCR. These...
Shigella dysenteriae Type 1-Specific Bacteriophage from Environmental Waters in Bangladesh
Faruque, Shah M., Chowdhury, Nityananda, Khan, Rasel, Hasan, M. Rubayet, Nahar, Jebun, Islam, M. Johirul, ...
Shigella dysenteriae type 1 is the causative agent of the most severe form of bacillary dysentery, which occurs as epidemics in many developing countries. We isolated a bacteriophage from surface...
Kahali, Soumen, Sarkar, Bhaswati, Rajendran, K., Khanam, Jasmina, Yamasaki, Shinji, Nandy, Ranjan K., ...
Enteroaggregative Escherichia coli (EAEC) is an important diarrheal enteropathogen defined by aggregative adherence to cultured epithelial cells. We have detected EAEC from 121 (6.6%) of 1,826...
Shima, Kensuke, Terajima, Jun, Sato, Toshio, Nishimura, Kazuhiko, Tamura, Kazumichi, Watanabe, Haruo, ...
Six characteristic regions (I to VI) were identified in Shiga toxin 2 (Stx2) phages (T. Sato, T. Shimizu, M. Watarai, M. Kobayashi, S. Kano, T. Hamabata, Y. Takeda, and S. Yamasaki, Gene 309:35-48,...
Faruque, Shah M., Bin Naser, Iftekhar, Fujihara, Kazutaka, Diraphat, Pornphan, Chowdhury, Nityananda, Kamruzzaman, M., ...
KSF-1Φ, a novel filamentous phage of Vibrio cholerae, supports morphogenesis of the RS1 satellite phage by heterologous DNA packaging and facilitates horizontal gene transfer. We analyzed the...
Bag, Prasanta K., Nandi, Suvobroto, Bhadra, Rupak K., Ramamurthy, T., Bhattacharya, S. K., Nishibuchi, M., ...
The genomes of the O3:K6 strains of Vibrio parahaemolyticus which abruptly emerged in Calcutta, India, in February 1996 and which demonstrated an unusual potential to spread and an enhanced...
Garg, Pallavi, Nandy, Ranjan K., Chaudhury, Papiya, Chowdhury, Nandini Roy, De, Keya, Ramamurthy, T., ...
The toxigenic Inaba serotype of Vibrio cholerae O1 biotype El Tor reappeared in India in 1998 and 1999, almost 10 years after its last dominance in Calcutta in 1989. Extensive molecular...
Virulence Genes in Environmental Strains of Vibrio cholerae
Chakraborty, Soumen, Mukhopadhyay, Asish K., Bhadra, Rupak Kumar, Ghosh, Amar Nath, Mitra, Rupak, Shimada, Toshio, ...
The virulence of a pathogen is dependent on a discrete set of genetic determinants and their well-regulated expression. The ctxAB and tcpA genes are known to play a cardinal role in maintaining...
Monoclonal Antibody to Shiga Toxin 2 Which Blocks Receptor Binding and Neutralizes Cytotoxicity
Nakao, Hiroshi, Kiyokawa, Nobutaka, Fujimoto, Junichiro, Yamasaki, Shinji, Takeda, Tae
A monoclonal antibody (MAb) was raised against Shiga toxin 2 (Stx2) of Escherichia coli O157:H7. MAb VTm1.1 belonged to the immunoglobulin G1 subclass and had a κ light chain, and it could...
Ogawa, Michinaga, Shimizu, Kensuke, Nomoto, Koji, Takahashi, Masatoshi, Watanuki, Masaaki, Tanaka, Ryuichiro, ...
We examined colonization patterns of Shiga toxin-producing Escherichia coli (STEC), concentrations of Shiga toxins (Stxs) and specific immunoglobulin A (lgA) against Stxs and STEC bacterial cell...
Watarai, Masahisa, Sato, Toshio, Kobayashi, Midori, Shimizu, Takeshi, Yamasaki, Shinji, Tobe, Toru, ...
Shiga toxins 1 (Stx1) and 2 (Stx2) are encoded by toxin-converting bacteriophages of Stx-producing Escherichia coli (STEC), and so far two Stx1- and one Stx2-converting phages have been isolated from...
Faruque, Shah M., Khan, Rasel, Kamruzzaman, M., Yamasaki, Shinji, Ahmad, Q. Shafi, Azim, Tasnim, ...
Bacillary dysentery caused by Shigella species is a public health problem in developing countries including Bangladesh. Although, shigellae-contaminated food and drinks are often the source of the...
Karasawa, Tadahiro, Ito, Hideaki, Tsukamoto, Teizo, Yamasaki, Shinji, Kurazono, Hisao, Faruque, Shah M., ...
We identified and characterized a gene encoding a homologue of the B subunits of cholera toxin (CTB) and heat-labile enterotoxin (LTB) of Escherichia coli from a clinical isolate of Citrobacter...
Sato, Toshio, Shimizu, Takeshi, Watarai, Masahisa, Kobayashi, Midori, Kano, Shigeyuki, Hamabata, Takashi, ...
Two Stx-converting phages, designated Stx1φ and Stx2φ-II, were isolated from an Escherichia coli O157:H7 strain, Morioka V526, and their entire nucleotide sequences were determined. The genomes of...
Pandey, Mritunjay, Khan, Asis, Das, Suresh C., Sarkar, Bhaswati, Kahali, Soumen, Chakraborty, Subhra, ...
Among Escherichia coli strains isolated from stool specimens from patients with acute diarrhea, 1.4% were found to harbor cdtB by use of enrichment cytolethal distending toxin (CDT) PCR. These...
Shigella dysenteriae Type 1-Specific Bacteriophage from Environmental Waters in Bangladesh
Faruque, Shah M., Chowdhury, Nityananda, Khan, Rasel, Hasan, M. Rubayet, Nahar, Jebun, Islam, M. Johirul, ...
Shigella dysenteriae type 1 is the causative agent of the most severe form of bacillary dysentery, which occurs as epidemics in many developing countries. We isolated a bacteriophage from surface...
Kahali, Soumen, Sarkar, Bhaswati, Rajendran, K., Khanam, Jasmina, Yamasaki, Shinji, Nandy, Ranjan K., ...
Enteroaggregative Escherichia coli (EAEC) is an important diarrheal enteropathogen defined by aggregative adherence to cultured epithelial cells. We have detected EAEC from 121 (6.6%) of 1,826...
Shima, Kensuke, Terajima, Jun, Sato, Toshio, Nishimura, Kazuhiko, Tamura, Kazumichi, Watanabe, Haruo, ...
Six characteristic regions (I to VI) were identified in Shiga toxin 2 (Stx2) phages (T. Sato, T. Shimizu, M. Watarai, M. Kobayashi, S. Kano, T. Hamabata, Y. Takeda, and S. Yamasaki, Gene 309:35-48,...
Faruque, Shah M., Bin Naser, Iftekhar, Fujihara, Kazutaka, Diraphat, Pornphan, Chowdhury, Nityananda, Kamruzzaman, M., ...
KSF-1Φ, a novel filamentous phage of Vibrio cholerae, supports morphogenesis of the RS1 satellite phage by heterologous DNA packaging and facilitates horizontal gene transfer. We analyzed the...
Shima, Kensuke, Wu, Yuluo, Sugimoto, Norihiko, Asakura, Masahiro, Nishimura, Kazuhiko, Yamasaki, Shinji
In this study, we compared a recently developed PCR-restriction fragment length polymorphism (PCR-RFLP) assay with pulsed-field gel electrophoresis (PFGE) using three different Shiga toxin-producing...
Asakura, Masahiro, Hinenoya, Atsushi, Alam, Mohammad S., Shima, Kensuke, Zahid, Shamim Hasan, Shi, Lei, ...
Cytolethal distending toxins (CDTs) are inhibitory cyclomodulins, which block eukaryotic cell proliferation and are produced by a diverse group of Gram-negative bacteria, including Escherichia coli...