Maruyama, Satoshi, Cheng, Jun, Shingaki, Susumu, Tamura, Takashi, Asakawa, Shuichi, Minoshima, Shinsei, ...
Abstract Background Among the salivary gland carcinomas, carcinoma in pleomorphic adenoma has been regarded as a representative carcinoma type which arises secondarily in the background of a...
Taku Okada, Masaru Tomita, Kazuhiko Kawasaki, Shinsei Minoshima
Nobuyoshi Shimizu 4
Mutationv Iew, Shinsei Minoshima, Susumu Mitsuyama, Saho Ohno, Takashi Kawamura, Nobuyoshi Shimizu
disease loci have been mapped to particular chromosomal regions and almost 800 disease-causing genes and the associated mutations have been identified. These mutation data are indispensable not only...
Masafumi Ohtsubo, Susumu Mitsuyama, Takashi Kawamura, Nobuyoshi Shimizu, Shinsei Minoshima
One of the important purposes of genome research is to elucidate the nature of genes responsible for monogenic as well as multigenic diseases. In order to better understand correlation between...
Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004)
Tadashi Imanishi, Takeshi Itoh, Yutaka Suzuki, Claire O'Donovan, Satoshi Fukuchi, Kanako O. Koyanagi, ...
An international team has systematically validated and annotated just over 21,000 human genes using full-length cDNA, thereby providing a valuable new resource for the human genetics community.
Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004)
Tadashi Imanishi, Takeshi Itoh, Yutaka Suzuki, Claire O'Donovan, Satoshi Fukuchi, Kanako O. Koyanagi, ...
The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...
Single-stranded DNA structure of a minisatellite sequence isolated from Acanthopagrus latus (2004)
Kato, Mikio, Hokabe, Shingo, Haku, Takeshi, Minoshima, Shinsei, Nagayama, Kuniaki, Shimizu, Nobuyoshi
Spiteri, Elizabeth, Babcock, Melanie, Kashork, Catherine D., Wakui, Keiko, Gogineni, Swarna, Lewis, Debbie A., ...
The chromosome 22q11.2 region is susceptible to rearrangements, mediated by low copy repeats (LCR22s). Deletions and duplications are mediated by homologous recombination events between LCR22s. The...
The Human Ribosomal Protein Genes: Sequencing and Comparative Analysis of 73 Genes (2002)
Yoshihama, Maki, Uechi, Tamayo, Asakawa, Shuichi, Kawasaki, Kazuhiko, Kato, Seishi, Higa, Sayomi, ...
Hokabe, Shingo, Gurkov, Theodor D., Okawara, Hiroshi, Nagayama, Kuniaki, Minoshima, Shinsei, Shimizu, Nobuyoshi, ...
Hokabe, Shingo, Gurkov, Theodor D., Okawara, Hiroshi, Nagayama, Kuniaki, Minoshima, Shinsei, Shimizu, Nobuyoshi, ...
The KMDB/MutationView: a mutation database for human disease genes (2001)
Minoshima, Shinsei, Mitsuyama, Susumu, Ohtsubo, Masafumi, Kawamura, Takashi, Ito, Sachiko, Shibamoto, Sayumi, ...
The KMDB/MutationView is a graphical database of mutations in human disease-causing genes and its current version consists of nine category-based sub-databases including diseases of eye, heart,...
Footz, Tim K., Brinkman-Mills, Polly, Banting, Graham S., Maier, Stephanie A., Riazi, M. Ali, Bridgland, Lindsay, ...
Keio Mutation Database (KMDB) for human disease gene mutations (2000)
Minoshima, Shinsei, Mitsuyama, Susumu, Ohno, Saho, Kawamura, Takashi, Shimizu, Nobuyoshi
A database of mutations in human disease-causing genes has been constructed and named as Keio Mutation Database (KMDB). This KMDB utilizes a database software called MutationView which was designed...
Isolation and Characterization of the Plasma Hyaluronan-Binding Protein (PHBP) Gene (HABP2) (1997)
Sumiya, Jun-ichi, Asakawa, Shuichi, Tobe, Takashi, Hashimoto, Ken, Saguchi, Ken-ichi, Choi-Miura, Nam-Ho, ...
PHBP is a novel human plasma hyaluronan-binding protein that shows significant homology in amino acid sequence to hepatocyte growth factor activator. Two overlapping clones that encode the human...
Chrast, Roman, Scott, Hamish S., Chen, Haiming, Kudoh, Jun, Rossier, Colette, Minoshima, Shinsei, ...
Kudoh, Jun, Nagamine, Kentaro, Asakawa, Shuichi, Abe, Izumi, Kawasaki, Kazuhiko, Maeda, Hideto, ...
As a step toward identifying the pathogenic genes for autoimmune polyglandular disease type I (APECED) and other disorders mapped to the PFKL locus on chromosome 21q22.3, we have constructed a...
GeneView: multi-language human gene mapping library with a graphical user interface (1993)
Dohi, Hiroshi, Ishizuka, Mitsuru, Minoshima, Shinsei, Shimizu, Nobuyoshi
GeneView is a newly developed human gene mapping library system that works on an X-Window platform. This system is designed for researchers who routinely utilize gene mapping data in the laboratory...
Human Long-Chain Acyl-CoA Synthetase: Structure and Chromosomal Location (1992)
Abe, Takaaki, Fujino, Takahiro, Fukuyama, Ryuichi, Minoshima, Shinsei, Shimizu, Nobuyoshi, Toh, Hiroyuki, ...
A complementary DNA clone encoding the entire human long-chain acyl-CoA synthetase was isolated and the total 698-amino acid sequence was deduced. The amino acid sequence of human long-chain acyl-CoA...
Autonomous Control of the Level of Methylation of Methyl-Accepting Chemotaxis Protein (1982)
HAYASHI, Hiroshi, MINOSHIMA, Shinsei, OHBA, Masataka
Methylation and demethylation of the methyl-accepting chemotaxis protein (MCP) was studied in vitro. The in vitro MCP methylating system showed the following characteristics. 1. Multiple bands of...
MINOSHIMA, Shinsei, OHBA, Masataka, HAYASHI, Hiroshi
An in vitro system for the methylation of methyl-accepting chemotaxis proteins (MCP's), which have been shown to be membrane integral proteins, was constructed. The system, consisting of the...
KOIWAI, Osamu, MINOSHIMA, Shinsei, HAYASHI, Hiroshi
Chemotactic Escherichia coli contains five major methyl-accepting proteins. Three of them were identified as the product of tsr gene, tar gene and peptide elongation factor Tu. Electro-phoretic...
MINOSHIMA, Shinsei, HAYASHI, Hiroshi
A membrane from Escherichia coli cheX mutants failed to accept the methyl-moiety when incubated with a cytoplasm of wild type bacteria. The possibility of reduced production of methyl-accepting...
Hox cluster genomics in the horn shark, Heterodontus francisci
Kim, Chang-Bae, Amemiya, Chris, Bailey, Wendy, Kawasaki, Kazuhiko, Mezey, Jason, Miller, Webb, ...
Reconstructing the evolutionary history of Hox cluster origins will lead to insights into the developmental and evolutionary significance of Hox gene clusters in vertebrate phylogeny and to their...
The KMDB/MutationView: a mutation database for human disease genes
Minoshima, Shinsei, Mitsuyama, Susumu, Ohtsubo, Masafumi, Kawamura, Takashi, Ito, Sachiko, Shibamoto, Sayumi, ...
The KMDB/MutationView is a graphical database of mutations in human disease-causing genes and its current version consists of nine category-based sub-databases including diseases of eye, heart, ear,...
Keio Mutation Database (KMDB) for human disease gene mutations
Minoshima, Shinsei, Mitsuyama, Susumu, Ohno, Saho, Kawamura, Takashi, Shimizu, Nobuyoshi
A database of mutations in human disease-causing genes has been constructed and named as Keio Mutation Database (KMDB). This KMDB utilizes a database software called MutationView which was designed...
Chrast, Roman, Scott, Hamish S., Chen, Haiming, Kudoh, Jun, Rossier, Colette, Minoshima, Shinsei, ...
As part of our effort to clone genes of human chromosome 21 that may contribute to Down syndrome, we have previously isolated four exons with homology to Drosophila single-minded (sim) gene, which...
A SNP Resource for Human Chromosome 22: Extracting Dense Clusters of SNPs From the Genomic Sequence
Dawson, Elisabeth, Chen, Yuan, Hunt, Sarah, Smink, Luc J., Hunt, Adrienne, Rice, Kate, ...
The recent publication of the complete sequence of human chromosome 22 provides a platform from which to investigate genomic sequence variation. We report the identification and characterization of...
Footz, Tim K., Brinkman-Mills, Polly, Banting, Graham S., Maier, Stephanie A., Riazi, M. Ali, Bridgland, Lindsay, ...
We have sequenced a 1.1-Mb region of human chromosome 22q containing the dosage-sensitive gene(s) responsible for cat eye syndrome (CES) as well as the 450-kb homologous region on mouse chromosome 6....
Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones
Imanishi, Tadashi, Itoh, Takeshi, Suzuki, Yutaka, O'Donovan, Claire, Fukuchi, Satoshi, Koyanagi, Kanako O, ...
The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...
Interarm Interaction of DNA Cruciform Forming at a Short Inverted Repeat Sequence
Kato, Mikio, Hokabe, Shingo, Itakura, Shuji, Minoshima, Shinsei, Lyubchenko, Yuri L., Gurkov, Theodor D., ...
A novel interarm interaction of DNA cruciform forming at inverted repeat sequence was characterized using an S1 nuclease digestion, permanganate oxidation, and microscopic imaging. An inverted repeat...
The Human Ribosomal Protein Genes: Sequencing and Comparative Analysis of 73 Genes
Yoshihama, Maki, Uechi, Tamayo, Asakawa, Shuichi, Kawasaki, Kazuhiko, Kato, Seishi, Higa, Sayomi, ...
The ribosome, as a catalyst for protein synthesis, is universal and essential for all organisms. Here we describe the structure of the genes encoding human ribosomal proteins (RPs) and compare this...
Hox cluster genomics in the horn shark, Heterodontus francisci
Kim, Chang-Bae, Amemiya, Chris, Bailey, Wendy, Kawasaki, Kazuhiko, Mezey, Jason, Miller, Webb, ...
Reconstructing the evolutionary history of Hox cluster origins will lead to insights into the developmental and evolutionary significance of Hox gene clusters in vertebrate phylogeny and to their...
The KMDB/MutationView: a mutation database for human disease genes
Minoshima, Shinsei, Mitsuyama, Susumu, Ohtsubo, Masafumi, Kawamura, Takashi, Ito, Sachiko, Shibamoto, Sayumi, ...
The KMDB/MutationView is a graphical database of mutations in human disease-causing genes and its current version consists of nine category-based sub-databases including diseases of eye, heart, ear,...
Keio Mutation Database (KMDB) for human disease gene mutations
Minoshima, Shinsei, Mitsuyama, Susumu, Ohno, Saho, Kawamura, Takashi, Shimizu, Nobuyoshi
A database of mutations in human disease-causing genes has been constructed and named as Keio Mutation Database (KMDB). This KMDB utilizes a database software called MutationView which was designed...
The Human Ribosomal Protein Genes: Sequencing and Comparative Analysis of 73 Genes
Yoshihama, Maki, Uechi, Tamayo, Asakawa, Shuichi, Kawasaki, Kazuhiko, Kato, Seishi, Higa, Sayomi, ...
The ribosome, as a catalyst for protein synthesis, is universal and essential for all organisms. Here we describe the structure of the genes encoding human ribosomal proteins (RPs) and compare this...
Chrast, Roman, Scott, Hamish S., Chen, Haiming, Kudoh, Jun, Rossier, Colette, Minoshima, Shinsei, ...
As part of our effort to clone genes of human chromosome 21 that may contribute to Down syndrome, we have previously isolated four exons with homology to Drosophila single-minded (sim) gene, which...
A SNP Resource for Human Chromosome 22: Extracting Dense Clusters of SNPs From the Genomic Sequence
Dawson, Elisabeth, Chen, Yuan, Hunt, Sarah, Smink, Luc J., Hunt, Adrienne, Rice, Kate, ...
The recent publication of the complete sequence of human chromosome 22 provides a platform from which to investigate genomic sequence variation. We report the identification and characterization of...
Footz, Tim K., Brinkman-Mills, Polly, Banting, Graham S., Maier, Stephanie A., Riazi, M. Ali, Bridgland, Lindsay, ...
We have sequenced a 1.1-Mb region of human chromosome 22q containing the dosage-sensitive gene(s) responsible for cat eye syndrome (CES) as well as the 450-kb homologous region on mouse chromosome 6....
Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones
Imanishi, Tadashi, Itoh, Takeshi, Suzuki, Yutaka, O'Donovan, Claire, Fukuchi, Satoshi, Koyanagi, Kanako O, ...
The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...
Interarm Interaction of DNA Cruciform Forming at a Short Inverted Repeat Sequence
Kato, Mikio, Hokabe, Shingo, Itakura, Shuji, Minoshima, Shinsei, Lyubchenko, Yuri L., Gurkov, Theodor D., ...
A novel interarm interaction of DNA cruciform forming at inverted repeat sequence was characterized using an S1 nuclease digestion, permanganate oxidation, and microscopic imaging. An inverted repeat...