Effect of WAVE2 Phosphorylation on Activation of the Arp2/3 Complex (2007)
Nakanishi, Osamu, Suetsugu, Shiro, Yamazaki, Daisuke, Takenawa, Tadaomi
Members of the family of WASP-family Verprolin homologous proteins (WAVEs) activate the Arp2/3 complex to induce actin polymerization. The WAVE family comprises three proteins, namely, WAVE1, WAVE2...
Effect of WAVE2 phosphorylation on activation of the Arp2/3 complex (2007)
Nakanishi, Osamu, Suetsugu, Shiro, Yamazaki, Daisuke, Takenawa, Tadaomi
Members of the family of WASP-family Verprolin homologous proteins (WAVEs) activate the Arp2/3 complex to induce actin polymerization. The WAVE family comprises three proteins, namely, WAVE1, WAVE2,...
Effect of WAVE2 phosphorylation on activation of the Arp2/3 complex (2007)
Nakanishi, Osamu, Suetsugu, Shiro, Yamazaki, Daisuke, Takenawa, Tadaomi
Members of the family of WASP-family Verprolin homologous proteins (WAVEs) activate the Arp2/3 complex to induce actin polymerization. The WAVE family comprises three proteins, namely, WAVE1, WAVE2,...
WAVE3 Functions as a Negative Regulator of LDOC1 (2005)
Mizutani, Kiyohito, Koike, Daisuke, Suetsugu, Shiro, Takenawa, Tadaomi
WAVE3 belongs to the Wiskott-Aldrich syndrome protein family that mediates actin reorganization through activation of the Arp2/3 complex. However, the physiological function of WAVE3 is poorly...
Yamaguchi, Hideki, Miki, Hiroaki, Suetsugu, Shiro, Ma, Le, Kirschner, Marc W., Takenawa, Tadaomi
All WASP family proteins share a common C terminus that consists of the verprolin homology domain (V), cofilin homology domain (C), and acidic region (A), through which they activate Arp2/3...
Regulation of actin cytoskeleton by mDab1 through N-WASP and ubiquitination of mDab1
Suetsugu, Shiro, Tezuka, Tohru, Morimura, Toshifumi, Hattori, Mitsuharu, Mikoshiba, Katsuhiko, Yamamoto, Tadashi, ...
Migration of cells is critical to development of the central nervous system. Reelin, which was identified from the reeler mutant mice having a defect in the multilamellar structure of the brain, is...
Park, Sun Joo, Suetsugu, Shiro, Takenawa, Tadaomi
Neural Wiskott–Aldrich syndrome protein (N-WASP) regulates reorganization of the actin cytoskeleton through activation of the Arp2/3 complex. Here, we show that heat shock protein 90 (HSP90)...
Yamaguchi, Hideki, Miki, Hiroaki, Suetsugu, Shiro, Ma, Le, Kirschner, Marc W., Takenawa, Tadaomi
All WASP family proteins share a common C terminus that consists of the verprolin homology domain (V), cofilin homology domain (C), and acidic region (A), through which they activate Arp2/3...
Regulation of actin cytoskeleton by mDab1 through N-WASP and ubiquitination of mDab1
Suetsugu, Shiro, Tezuka, Tohru, Morimura, Toshifumi, Hattori, Mitsuharu, Mikoshiba, Katsuhiko, Yamamoto, Tadashi, ...
Migration of cells is critical to development of the central nervous system. Reelin, which was identified from the reeler mutant mice having a defect in the multilamellar structure of the brain, is...
Park, Sun Joo, Suetsugu, Shiro, Takenawa, Tadaomi
Neural Wiskott–Aldrich syndrome protein (N-WASP) regulates reorganization of the actin cytoskeleton through activation of the Arp2/3 complex. Here, we show that heat shock protein 90 (HSP90)...
Tsujita, Kazuya, Suetsugu, Shiro, Sasaki, Nobunari, Furutani, Masahiro, Oikawa, Tsukasa, Takenawa, Tadaomi
The conserved FER-CIP4 homology (FCH) domain is found in the pombe Cdc15 homology (PCH) protein family members, including formin-binding protein 17 (FBP17). However, the amino acid sequence homology...
Optimization of WAVE2 complex–induced actin polymerization by membrane-bound IRSp53, PIP3, and Rac
Suetsugu, Shiro, Kurisu, Shusaku, Oikawa, Tsukasa, Yamazaki, Daisuke, Oda, Atsushi, Takenawa, Tadaomi
WAVE2 activates the actin-related protein (Arp) 2/3 complex for Rac-induced actin polymerization during lamellipodium formation and exists as a large WAVE2 protein complex with Sra1/PIR121, Nap1,...
Yanagida-Asanuma, Etsuko, Asanuma, Katsuhiko, Kim, Kwanghee, Donnelly, Mary, Young Choi, Hoon, Hyung Chang, Jae, ...
The actin-based foot processes of kidney podocytes and the interposed slit diaphragm form the final barrier to proteinuria. Mutations affecting several podocyte proteins cause disruption of the...
Fukuoka, Maiko, Suetsugu, Shiro, Miki, Hiroaki, Fukami, Kiyoko, Endo, Takeshi, Takenawa, Tadaomi
We identified a novel adaptor protein that contains a Src homology (SH)3 domain, SH3 binding proline-rich sequences, and a leucine zipper-like motif and termed this protein WASP interacting SH3...
Takano, Kazunori, Toyooka, Kiminori, Suetsugu , Shiro
Correction to: The EMBO Journal (2008) 27, 2817–2828. doi:10.1038/emboj.2008.216
Takano, Kazunari, Toyooka, Kiminori, Suetsugu, Shiro
Extended Fer-CIP4 homology (EFC)/FCH-BAR (F-BAR) domains generate and bind to tubular membrane structures of defined diameters that are involved in the formation and fission of endocytotic vesicles....