Population-specific GSTM1 copy number variation (2009)
Huang, R. Stephanie, Chen, Peixian, Wisel, Steve, Duan, Shiwei, Zhang, Wei, Cook, Edwin H., ...
As one of the major glutathione conjugation enzymes, GSTM1 detoxifies a number of drugs and xenobiotics. Its expression and activity have been shown to correlate both with cancer risks and drug...
HapMap filter 1.0: A tool to preprocess the HapMap genotypic data for association studies (2008)
Wei Zhang, Shiwei Duan, M. Eileen Dolan
The International HapMap Project provides a resource of genotypic data on single nucleotide polymorphisms (SNPs), which can be used in various association studies to identify the genetic determinants...
Shiwei Duan, Wei Zhang, Wasim Kamal Bleibel, Nancy Jean Cox, M. Eileen Dolan
The Affymetrix GeneChip® Human Exon 1.0 ST array (exon array) is designed to measure both gene-level and exon-level expression in human samples. This exon array contains ~1.4 million probesets...
FstSNP-HapMap3: a database of SNPs with high population differentiation for HapMap3 (2008)
Shiwei Duan, Wei Zhang, Nancy Jean Cox, Mary Eileen Dolan
The International HapMap Project has recently made available genotypes and frequency data for phase 3 (NCBI build 36, dbSNP b129) of the HapMap providing an enriched genotype dataset for...
Huang, R. Stephanie, Duan, Shiwei, Bleibel, Wasim K., Kistner, Emily O., Zhang, Wei, Clark, Tyson A., ...
Large interindividual variance has been observed in sensitivity to drugs. To comprehensively decipher the genetic contribution to these variations in drug susceptibility, we present a genome-wide...
HapMap filter 1.0: A tool to preprocess the HapMap genotypic data for association studies
Zhang, Wei, Duan, Shiwei, Dolan, M Eileen
The International HapMap Project provides a resource of genotypic data on single nucleotide polymorphisms (SNPs), which can be used in various association studies to identify the genetic determinants...
Duan, Shiwei, Zhang, Wei, Bleibel, Wasim Kamel, Cox, Nancy Jean, Dolan, M Eileen
The Affymetrix GeneChip® Human Exon 1.0 ST array (exon array) is designed to measure both gene-level and exon-level expression in human samples. This exon array contains ~1.4 million probesets...
FstSNP-HapMap3: a database of SNPs with high population differentiation for HapMap3
Duan, Shiwei, Zhang, Wei, Cox, Nancy Jean, Dolan, Mary Eileen
The International HapMap Project has recently made available genotypes and frequency data for phase 3 (NCBI build 36, dbSNPb129) of the HapMap providing an enriched genotype dataset for approximately...
Evaluation of Genetic Variation Contributing to Differences in Gene Expression between Populations
Zhang, Wei, Duan, Shiwei, Kistner, Emily O., Bleibel, Wasim K., Huang, R. Stephanie, Clark, Tyson A., ...
Gene expression is a complex quantitative trait partially regulated by genetic variation in DNA sequence. Population differences in gene expression could contribute to some of the observed...
Evaluation of Genetic Variation Contributing to Differences in Gene Expression between Populations
Zhang, Wei, Duan, Shiwei, Kistner, Emily O., Bleibel, Wasim K., Huang, R. Stephanie, Clark, Tyson A., ...
Genetic Architecture of Transcript-Level Variation in Humans
Duan, Shiwei, Huang, R. Stephanie, Zhang, Wei, Bleibel, Wasim K., Roe, Cheryl A., Clark, Tyson A., ...
We report here the results of testing the pairwise association of 12,747 transcriptional gene-expression values with more than two million single-nucleotide polymorphisms (SNPs) in samples of...
Hartford, Christine M., Duan, Shiwei, Delaney, Shannon M., Mi, Shuangli, Kistner, Emily O., Lamba, Jatinder K., ...
Cytarabine arabinoside (ara-C) is an antimetabolite used to treat hematologic malignancies. Resistance is a common reason for treatment failure with adverse side effects contributing to morbidity and...