BioMed Central Open Access (2008)
Gul S Dalgin, Gabriela Alexe, Daniel Scanfeld, Pablo Tamayo, Jill P Mesirov, Shridar Ganesan, ...
This is an Open Access article distributed under the terms of the Creative Commons Attribution License
Hall, Bonnie H, Ianosi-Irimie, Monica, Javidian, Parisa, Chen, Wenjin, Ganesan, Shridar, Foran, David J
Abstract Background Breast cancers that overexpress the human epidermal growth factor receptor 2 (HER2) are eligible for effective biologically targeted therapies, such as trastuzumab. However,...
Gabriela Alexe, Gul S. Dalgin, Daniel Scanfeld, Pablo Tamayo, Jill Mesirov, Charles Delisi, ...
expression of lymphocyte-associated genes in node negative HER2+ breast
Portraits of breast cancer progression (2007)
Dalgin, Gul S, Alexe, Gabriela, Scanfeld, Daniel, Tamayo, Pablo, Mesirov, Jill P, Ganesan, Shridar, ...
Abstract Background Clustering analysis of microarray data is often criticized for giving ambiguous results because of sensitivity to data perturbation or clustering techniques used. In this paper,...
Kanellopoulou, Chryssa, Muljo, Stefan A., Kung, Andrew L., Ganesan, Shridar, Drapkin, Ronny, Jenuwein, Thomas, ...
Dicer is the enzyme that cleaves double-stranded RNA (dsRNA) into 21–25-nt-long species responsible for sequence-specific RNA-induced gene silencing at the transcriptional, post-transcriptional, or...
Cantor, Sharon B., Bell, Daphne W., Ganesan, Shridar, Kass, Elizabeth M., Drapkin, Ronny, Grossman, Steven R., ...
BRCA1 interacts in vivo with a novel protein, BACH1, a member of the DEAH helicase family. BACH1 binds directly to the BRCT repeats of BRCA1. A BACH1 derivative, bearing a mutation in a residue that...
Tumorigenesis in mice carrying a truncating Brca1 mutation (2001)
Ludwig, Thomas, Fisher, Peter, Ganesan, Shridar, Efstratiadis, Argiris
Tumorigenesis in mice carrying a truncating Brca1 mutation
Ludwig, Thomas, Fisher, Peter, Ganesan, Shridar, Efstratiadis, Argiris
We generated mouse mutants carrying in the Brca1 locus a modification (Brca1tr) that eliminates the C-terminal half of the protein product and obtained results indicating that, depending on genetic...
Kanellopoulou, Chryssa, Muljo, Stefan A., Kung, Andrew L., Ganesan, Shridar, Drapkin, Ronny, Jenuwein, Thomas, ...
Dicer is the enzyme that cleaves double-stranded RNA (dsRNA) into 21–25-nt-long species responsible for sequence-specific RNA-induced gene silencing at the transcriptional, post-transcriptional, or...
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses
Masutomi, Kenkichi, Possemato, Richard, Wong, Judy M. Y., Currier, Jennifer L., Tothova, Zuzana, Manola, Judith B., ...
Constitutive expression of telomerase prevents senescence and crisis by maintaining telomere homeostasis. However, recent evidence suggests that telomerase is dynamically regulated in normal cells...
Tumorigenesis in mice carrying a truncating Brca1 mutation
Ludwig, Thomas, Fisher, Peter, Ganesan, Shridar, Efstratiadis, Argiris
We generated mouse mutants carrying in the Brca1 locus a modification (Brca1tr) that eliminates the C-terminal half of the protein product and obtained results indicating that, depending on genetic...
Kanellopoulou, Chryssa, Muljo, Stefan A., Kung, Andrew L., Ganesan, Shridar, Drapkin, Ronny, Jenuwein, Thomas, ...
Dicer is the enzyme that cleaves double-stranded RNA (dsRNA) into 21–25-nt-long species responsible for sequence-specific RNA-induced gene silencing at the transcriptional, post-transcriptional, or...
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses
Masutomi, Kenkichi, Possemato, Richard, Wong, Judy M. Y., Currier, Jennifer L., Tothova, Zuzana, Manola, Judith B., ...
Constitutive expression of telomerase prevents senescence and crisis by maintaining telomere homeostasis. However, recent evidence suggests that telomerase is dynamically regulated in normal cells...
Association of BRCA1 with the inactive X chromosome and XIST RNA.
Ganesan, Shridar, Silver, Daniel P, Drapkin, Ronny, Greenberg, Roger, Feunteun, Jean, Livingston, David M
Breast cancer, early onset 1 (BRCA1) encodes a nuclear protein that participates in breast and ovarian cancer suppression. The molecular basis for the gender and tissue specificity of the BRCA1...
Portraits of breast cancer progression
Dalgin, Gul S, Alexe, Gabriela, Scanfeld, Daniel, Tamayo, Pablo, Mesirov, Jill P, Ganesan, Shridar, ...