Shuichi Asakawa

Establishment and characterization of pleomorphic adenoma cell systems: an in-vitro demonstration of carcinomas arising secondarily from adenomas in the salivary gland (2009)

Maruyama, Satoshi, Cheng, Jun, Shingaki, Susumu, Tamura, Takashi, Asakawa, Shuichi, Minoshima, Shinsei, ...

Abstract Background Among the salivary gland carcinomas, carcinoma in pleomorphic adenoma has been regarded as a representative carcinoma type which arises secondarily in the background of a...

UTGB/medaka: genomic resource database for medaka biology (2008)

Ahsan, Budrul, Kobayashi, Daisuke, Yamada, Tomoyuki, Kasahara, Masahiro, Sasaki, Shin, Saito, Taro L., ...

Medaka (Oryzias latipes) is a small egg-laying freshwater teleost native to East Asia that has become an excellent model system for developmental genetics and evolutionary biology. The draft medaka...

Radiation Hybrid Maps of Medaka Chromosomes LG 12, 17, and 22 (2007)

Su, Feng, Osada, Yumi, Ekker, Marc, Chevrette, Mario, Shimizu, Atsushi, Asakawa, Shuichi, ...

The Medaka is an excellent genetic system for studies of vertebrate development and disease and environmental and evolutionary biology studies. To facilitate the mapping of markers or the cloning of...

The DNA sequence of medaka chromosome LG22 (2007)

Sasaki, Takashi, Shimizu, Atsushi, Ishikawa, Sabine K., Imai, Shuichiro, Asakawa, Shuichi, Murayama, Yuji, ...

We report the genomic DNA sequence of a single chromosome (linkage group 22; LG22) of the small teleost fish medaka (Oryzias latipes) as a first whole chromosome sequence from a non-mammalian...

Genomic organization of the sex-determining and adjacent regions of the sex chromosomes of medaka (2006)

Kondo, Mariko, Hornung, Ute, Nanda, Indrajit, Imai, Shuichiro, Sasaki, Takashi, Shimizu, Atsushi, ...

Sequencing of the human Y chromosome has uncovered the peculiarities of the genomic organization of a heterogametic sex chromosome of old evolutionary age, and has led to many insights into the...

Genomic organization of the sex-determining and adjacent regions of the sex chromosomes of medaka (2006)

Kondo, Mariko, Hornung, Ute, Nanda, Indrajit, Imai, Shuichiro, Sasaki, Takashi, Shimizu, Atsushi, ...

Sequencing of the human Y chromosome has uncovered the peculiarities of the genomic organization of a heterogametic sex chromosome of old evolutionary age, and has led to many insights into the...

Polymorphic segmental duplications at 8p23.1 challenge the determination of individual defensin gene repertoires and the assembly of a contiguous human reference sequence (2004)

Taudien, Stefan, Galgoczy, Petra, Huse, Klaus, Reichwald, Kathrin, Schilhabel, Markus, Szafranski, Karol, ...

Abstract Background Defensins are important components of innate immunity to combat bacterial and viral infections, and can even elicit antitumor responses. Clusters of defensin (DEF) genes are...

A first generation physical map of the medaka genome in BACs essential for positional cloning and clone-by-clone based genomic sequencing (2004)

Khorasani,Maryam Zadeh, Hennig,Steffen, Imre,Gabriele, Asakawa,Shuichi, Palczewski,Stefanie, Berger,Anja, ...

In order to realize the full potential of the medaka as a model system for developmental biology and genetics, characterized genomic resources need to be established, culminating in the sequence of...

A first generation physical map of the medaka genome in BACs essential for positional cloning and clone-by-clone based genomic sequencing (2004)

Khorasani, Maryam Zadeh, Hennig, Steffen, Imre, Gabriele, Asakawa, Shuichi, Palczewski, Stefanie, Berger, Anja, ...

In order to realize the full potential of the medaka as a model system for developmental biology and genetics, characterized genomic resources need to be established, culminating in the sequence of...

BioMed Central (2004)

Bmc Genomics, Stefan Taudien, Petra Galgoczy, Klaus Huse, Kathrin Reichwald, Markus Schilhabel, ...

Research article Polymorphic segmental duplications at 8p23.1 challenge the determination of individual defensin gene repertoires and the assembly of a contiguous human reference sequence

Genomic Structure and Expression of the Soluble Guanylyl Cyclase α2 Subunit Gene in the Medaka Fish Oryzias latipes (2003)

Yao, Yuko, Yamamoto, Takehiro, Tsutsumi, Makiko, Matsuda, Masaru, Hori, Hiroshi, Naruse, Kiyoshi, ...

A cDNA clone encoding the soluble guanylyl cyclase α2 subunit was isolated from medaka fish (Oryzias latipes) and designated as OIGCS-α2. The OIGCS-α2 cDNA was 3192 bp in length and the open...

Isolation and Characterization of the Plasma Hyaluronan-Binding Protein (PHBP) Gene (HABP2) (1997)

Sumiya, Jun-ichi, Asakawa, Shuichi, Tobe, Takashi, Hashimoto, Ken, Saguchi, Ken-ichi, Choi-Miura, Nam-Ho, ...

PHBP is a novel human plasma hyaluronan-binding protein that shows significant homology in amino acid sequence to hepatocyte growth factor activator. Two overlapping clones that encode the human...

Genomic Organization of the OS-9 Gene Amplified in Human Sarcomas (1997)

Kimura, Yukiko, Nakazawa, Megumi, Tsuchiya, Naoto, Asakawa, Shuichi, Shimizu, Nobuyoshi, Yamada, Michiyuki

The OS-9 gene is frequently amplified in human sarcomas. We isolated and characterized an OS-9 genomic DNA from a human BAC library. Sequencing of the genomic DNA showed that the gene spanned...

A 3-Mb Sequence-Ready Contig Map Encompassing the Multiple Disease Gene Cluster on Chromosome 11q13.1-q13.3 (1997)

Kitamura, Eiko, Hosoda, Fumie, Fukushima, Michiyo, Asakawa, Shuichi, Shimizu, Nobuyoshi, Imai, Takashi, ...

Despite the presence of several human disease genes on chromosome 11q13, few of them have been molecularly cloned. Here, we report the construction of a contig map encompassing 11q13.1–q13.3 using...

Localization of 16 Exons to a 450-kb Region Involved in the Autoimmune Polyglandular Disease Type I (APECED) on Human Chromosome 21q22.3 (1997)

Kudoh, Jun, Nagamine, Kentaro, Asakawa, Shuichi, Abe, Izumi, Kawasaki, Kazuhiko, Maeda, Hideto, ...

As a step toward identifying the pathogenic genes for autoimmune polyglandular disease type I (APECED) and other disorders mapped to the PFKL locus on chromosome 21q22.3, we have constructed a...

Wpkci, Encoding an Altered Form of PKCI, Is Conserved Widely on the Avian W Chromosome and Expressed in Early Female Embryos: Implication of Its Role in Female Sex Determination

Hori, Tetsuya, Asakawa, Shuichi, Itoh, Yuichiro, Shimizu, Nobuyoshi, Mizuno, Shigeki

Two W chromosome–linked cDNA clones, p5fm2 and p5fm3, were obtained from a subtracted (female minus male) cDNA library prepared from a mixture of undifferentiated gonads and mesonephroi of male or...

A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes

Nanda, Indrajit, Kondo, Mariko, Hornung, Ute, Asakawa, Shuichi, Winkler, Christoph, Shimizu, Atsushi, ...

The genes that determine the development of the male or female sex are known in Caenorhabditis elegans, Drosophila, and most mammals. In many other organisms the existence of sex-determining factors...

The Human Ribosomal Protein Genes: Sequencing and Comparative Analysis of 73 Genes

Yoshihama, Maki, Uechi, Tamayo, Asakawa, Shuichi, Kawasaki, Kazuhiko, Kato, Seishi, Higa, Sayomi, ...

The ribosome, as a catalyst for protein synthesis, is universal and essential for all organisms. Here we describe the structure of the genes encoding human ribosomal proteins (RPs) and compare this...

Conserved Function of Medaka pink-eyed dilution in Melanin Synthesis and Its Divergent Transcriptional Regulation in Gonads Among Vertebrates

Fukamachi, Shoji, Asakawa, Shuichi, Wakamatsu, Yuko, Shimizu, Nobuyoshi, Mitani, Hiroshi, Shima, Akihiro

Medaka is emerging as a model organism for the study of vertebrate development and genetics, and its effectiveness in forward genetics should prove equal to that of zebrafish. Here, we identify by...

Wpkci, Encoding an Altered Form of PKCI, Is Conserved Widely on the Avian W Chromosome and Expressed in Early Female Embryos: Implication of Its Role in Female Sex Determination

Hori, Tetsuya, Asakawa, Shuichi, Itoh, Yuichiro, Shimizu, Nobuyoshi, Mizuno, Shigeki

Two W chromosome–linked cDNA clones, p5fm2 and p5fm3, were obtained from a subtracted (female minus male) cDNA library prepared from a mixture of undifferentiated gonads and mesonephroi of male or...

A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes

Nanda, Indrajit, Kondo, Mariko, Hornung, Ute, Asakawa, Shuichi, Winkler, Christoph, Shimizu, Atsushi, ...

The genes that determine the development of the male or female sex are known in Caenorhabditis elegans, Drosophila, and most mammals. In many other organisms the existence of sex-determining factors...

The Human Ribosomal Protein Genes: Sequencing and Comparative Analysis of 73 Genes

Yoshihama, Maki, Uechi, Tamayo, Asakawa, Shuichi, Kawasaki, Kazuhiko, Kato, Seishi, Higa, Sayomi, ...

The ribosome, as a catalyst for protein synthesis, is universal and essential for all organisms. Here we describe the structure of the genes encoding human ribosomal proteins (RPs) and compare this...

Conserved Function of Medaka pink-eyed dilution in Melanin Synthesis and Its Divergent Transcriptional Regulation in Gonads Among Vertebrates

Fukamachi, Shoji, Asakawa, Shuichi, Wakamatsu, Yuko, Shimizu, Nobuyoshi, Mitani, Hiroshi, Shima, Akihiro

Medaka is emerging as a model organism for the study of vertebrate development and genetics, and its effectiveness in forward genetics should prove equal to that of zebrafish. Here, we identify by...

Genomic organization of the sex-determining and adjacent regions of the sex chromosomes of medaka

Kondo, Mariko, Hornung, Ute, Nanda, Indrajit, Imai, Shuichiro, Sasaki, Takashi, Shimizu, Atsushi, ...

Sequencing of the human Y chromosome has uncovered the peculiarities of the genomic organization of a heterogametic sex chromosome of old evolutionary age, and has led to many insights into the...

The hotei mutation of medaka in the anti-Müllerian hormone receptor causes the dysregulation of germ cell and sexual development

Morinaga, Chikako, Saito, Daisuke, Nakamura, Shuhei, Sasaki, Takashi, Asakawa, Shuichi, Shimizu, Nobuyoshi, ...

We previously performed mutant screens in the medaka for defects in gonadal development and identified a mutant of interest in this regard, which was designated as hotei (hot). This mutant manifests...

UTGB/medaka: genomic resource database for medaka biology

Ahsan, Budrul, Kobayashi, Daisuke, Yamada, Tomoyuki, Kasahara, Masahiro, Sasaki, Shin, Saito, Taro L., ...

Medaka (Oryzias latipes) is a small egg-laying freshwater teleost native to East Asia that has become an excellent model system for developmental genetics and evolutionary biology. The draft medaka...

Polycystic Kidney Disease in the Medaka (Oryzias latipes) pc Mutant Caused by a Mutation in the Gli-Similar3 (glis3) Gene

Hashimoto, Hisashi, Miyamoto, Rieko, Watanabe, Naoki, Shiba, Dai, Ozato, Kenjiro, Inoue, Chikako, ...

Polycystic kidney disease (PKD) is a common hereditary disease in humans. Recent studies have shown an increasing number of ciliary genes that are involved in the pathogenesis of PKD. In this study,...

Radiation Hybrid Maps of Medaka Chromosomes LG 12, 17, and 22

Su, Feng, Osada, Yumi, Ekker, Marc, Chevrette, Mario, Shimizu, Atsushi, Asakawa, Shuichi, ...

The Medaka is an excellent genetic system for studies of vertebrate development and disease and environmental and evolutionary biology studies. To facilitate the mapping of markers or the cloning of...