Horesh, Yair, Doniger, Tirza, Michaeli, Shulamit, Unger, Ron
Abstract Background In recent years, RNA molecules that are not translated into proteins (ncRNAs) have drawn a great deal of attention, as they were shown to be involved in many cellular functions....
Xu, Yu-xin, Ben-Shlomo, Herzel, Michaeli, Shulamit
Fractionation of the abundant small ribonucleoproteins (RNPs) of the trypanosomatid Leptomonas collosoma revealed the existence of a group of unidentified small RNPs that were shown to fractionate...
Small nucleolar RNA interference induced by antisense or double-stranded RNA in trypanosomatids
Liang, Xue-hai, Liu, Qing, Michaeli, Shulamit
In trypanosomes the C/D- and H/ACA-like small nucleolar RNAs (snoRNAs) are clustered and repeated in the genome. The snoRNAs studied to date are transcribed as polycistronic transcripts by RNA...
trans and cis Splicing in Trypanosomatids: Mechanism, Factors, and Regulation
Liang, Xue-hai, Haritan, Asaf, Uliel, Shai, Michaeli, Shulamit
Scanning electron microscopy of cells and tissues under fully hydrated conditions
Thiberge, Stephan, Nechushtan, Amotz, Sprinzak, David, Gileadi, Opher, Behar, Vered, Zik, Ory, ...
A capability for scanning electron microscopy of wet biological specimens is presented. A membrane that is transparent to electrons protects the fully hydrated sample from the vacuum. The result is a...
Liang, Xue-Hai, Xu, Yu-Xin, Michaeli, Shulamit
The spliced leader-associated (SLA1) RNA is a trypanosome-specific small RNA with unknown function. SLA1 carries a Sm-like site, and is associated with core Sm proteins. Here we found that SLA1...
LIANG, XUE-HAI, ULIEL, SHAI, HURY, AVRAHAM, BARTH, SARIT, DONIGER, TIRZA, UNGER, RON, ...
Small nucleolar RNAs (snoRNAs) constitute newly discovered noncoding small RNAs, most of which function in guiding modifications such as 2′-O-ribose methylation and pseudouridylation on rRNAs and...
The Genome of the Kinetoplastid Parasite, Leishmania major
Ivens, Alasdair C., Peacock, Christopher S., Worthey, Elizabeth A., Murphy, Lee, Aggarwal, Gautam, Berriman, Matthew, ...
Xu, Yu-xin, Ben-Shlomo, Herzel, Michaeli, Shulamit
Fractionation of the abundant small ribonucleoproteins (RNPs) of the trypanosomatid Leptomonas collosoma revealed the existence of a group of unidentified small RNPs that were shown to fractionate...
Small nucleolar RNA interference induced by antisense or double-stranded RNA in trypanosomatids
Liang, Xue-hai, Liu, Qing, Michaeli, Shulamit
In trypanosomes the C/D- and H/ACA-like small nucleolar RNAs (snoRNAs) are clustered and repeated in the genome. The snoRNAs studied to date are transcribed as polycistronic transcripts by RNA...
trans and cis Splicing in Trypanosomatids: Mechanism, Factors, and Regulation
Liang, Xue-hai, Haritan, Asaf, Uliel, Shai, Michaeli, Shulamit
Scanning electron microscopy of cells and tissues under fully hydrated conditions
Thiberge, Stephan, Nechushtan, Amotz, Sprinzak, David, Gileadi, Opher, Behar, Vered, Zik, Ory, ...
A capability for scanning electron microscopy of wet biological specimens is presented. A membrane that is transparent to electrons protects the fully hydrated sample from the vacuum. The result is a...
Liang, Xue-Hai, Xu, Yu-Xin, Michaeli, Shulamit
The spliced leader-associated (SLA1) RNA is a trypanosome-specific small RNA with unknown function. SLA1 carries a Sm-like site, and is associated with core Sm proteins. Here we found that SLA1...
LIANG, XUE-HAI, ULIEL, SHAI, HURY, AVRAHAM, BARTH, SARIT, DONIGER, TIRZA, UNGER, RON, ...
Small nucleolar RNAs (snoRNAs) constitute newly discovered noncoding small RNAs, most of which function in guiding modifications such as 2′-O-ribose methylation and pseudouridylation on rRNAs and...
Tkacz, Itai Dov, Lustig, Yaniv, Stern, Michael Zeev, Biton, Moshe, Salmon-Divon, Mali, Das, Anish, ...
In eukaryotes the seven Sm core proteins bind to U1, U2, U4, and U5 snRNAs. In Trypanosoma brucei, Sm proteins have been implicated in binding both spliced leader (SL) and U snRNAs. In this study, we...
Liang, Xue-hai, Hury, Avraham, Hoze, Ehud, Uliel, Shai, Myslyuk, Inna, Apatoff, Avihay, ...
Small nucleolar RNAs (snoRNAs) are a large group of noncoding RNAs that exist in eukaryotes and archaea and guide modifications such as 2′-O-ribose methylations and pseudouridylation on rRNAs and...
Lustig, Yaniv, Vagima, Yaron, Goldshmidt, Hanoch, Erlanger, Avigail, Ozeri, Vered, Vince, James, ...
Protein translocation across the endoplasmic reticulum is mediated by the signal recognition particle (SRP). In this study, the SRP pathway in trypanosomatids was down-regulated by two approaches:...
Spliced-leader RNA silencing: a novel stress-induced mechanism in Trypanosoma brucei
Lustig, Yaniv, Sheiner, Lilach, Vagima, Yaron, Goldshmidt, Hanoch, Das, Anish, Bellofatto, Vivian, ...
The signal-recognition particle (SRP) mediates the translocation of membrane and secretory proteins across the endoplasmic reticulum upon interaction with the SRP receptor. In trypanosomes, the main...
Elucidating the Role of C/D snoRNA in rRNA Processing and Modification in Trypanosoma brucei▿ †
Barth, Sarit, Shalem, Boaz, Hury, Avraham, Tkacz, Itai Dov, Liang, Xue-hai, Uliel, Shai, ...
Most eukaryotic C/D small nucleolar RNAs (snoRNAs) guide 2′-O methylation (Nm) on rRNA and are also involved in rRNA processing. The four core proteins that bind C/D snoRNA in Trypanosoma brucei...