Shun-Cheng Li

Retinoic acid enhances skeletal muscle progenitor formation and bypasses inhibition by bone morphogenetic protein 4 but not dominant negative β-catenin (2009)

Kennedy, Karen AM, Porter, Tammy, Mehta, Virja, Ryan, Scott D, Price, Feodor, Peshdary, Vian, ...

Abstract Background Understanding stem cell differentiation is essential for the future design of cell therapies. While retinoic acid (RA) is the most potent small molecule enhancer of skeletal...

High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif

Li, Shun-Cheng, Songyang, Zhou, Vincent, Sébastien J. F., Zwahlen, Catherine, Wiley, Sandra, Cantley, Lewis, ...

The phosphotyrosine-binding (PTB) domain is a recently identified protein module that has been characterized as binding to phosphopeptides containing an NPXpY motif (X = any amino acid). We describe...

A ‘three-pronged’ binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome

Hwang, Peter M., Li, Chengjun, Morra, Massimo, Lillywhite, Jennifer, Muhandiram, D.Ranjith, Gertler, Frank, ...

The SH2 domain protein SAP/SH2D1A, encoded by the X-linked lymphoproliferative (XLP) syndrome gene, associates with the hematopoietic cell surface receptor SLAM in a phosphorylation-independent...

Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb

Zwahlen, Catherine, Li, Shun-Cheng, Kay, Lewis E., Pawson, Tony, Forman-Kay, Julie D.

The phosphotyrosine-binding (PTB) domain of the cell fate determinant Numb is involved in the formation of multiple protein complexes in vivo and can bind a diverse array of peptide sequences in...

High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif

Li, Shun-Cheng, Songyang, Zhou, Vincent, Sébastien J. F., Zwahlen, Catherine, Wiley, Sandra, Cantley, Lewis, ...

The phosphotyrosine-binding (PTB) domain is a recently identified protein module that has been characterized as binding to phosphopeptides containing an NPXpY motif (X = any amino acid). We describe...

A ‘three-pronged’ binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome

Hwang, Peter M., Li, Chengjun, Morra, Massimo, Lillywhite, Jennifer, Muhandiram, D.Ranjith, Gertler, Frank, ...

The SH2 domain protein SAP/SH2D1A, encoded by the X-linked lymphoproliferative (XLP) syndrome gene, associates with the hematopoietic cell surface receptor SLAM in a phosphorylation-independent...

Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb

Zwahlen, Catherine, Li, Shun-Cheng, Kay, Lewis E., Pawson, Tony, Forman-Kay, Julie D.

The phosphotyrosine-binding (PTB) domain of the cell fate determinant Numb is involved in the formation of multiple protein complexes in vivo and can bind a diverse array of peptide sequences in...