Si-Jie Tan

Y chromosome evidence of earliest modern human settlement in East Asia and multiple origins of Tibetan and Japanese populations

Shi, Hong, Zhong, Hua, Peng, Yi, Dong, Yong-Li, Qi, Xue-Bin, Zhang, Feng, ...

Winter Temperature and UV Are Tightly Linked to Genetic Changes in the p53 Tumor Suppressor Pathway in Eastern Asia

Shi, Hong, Tan, Si-jie, Zhong, Hua, Hu, Wenwei, Levine, Arnold, Xiao, Chun-jie, ...

The tumor suppressor p53 is a master sensor of stress. Two human-specific polymorphisms, p53 codon 72 and MDM2 SNP309, influence the activities of p53. There is a tight association between cold...