Siddhartha P. Sarma

NMR assignment of $^2H$, $^{13}C$ and $^{15}N$ labeled amino-terminal domain of apo-pantothenate synthetase from E. coli (2006)

Chakrabarti, Kalyan Sundar, Sarma, Siddhartha P

Pantothenate (vitamin $b_5$) is an essential precursor for the biosynthesis of coenzyme A (CoA), an essential metabolite for many important cellular processes (Brown et al., 1987). Pantothenate...

NMR assignment of $^2H$, $^{13}C$ and $^{15}N$ labeled amino-terminal domain of apo-pantothenate synthetase from E. coli (2006)

Chakrabarti, Kalyan Sundar, Sarma, Siddhartha P

Pantothenate (vitamin $b_5$) is an essential precursor for the biosynthesis of coenzyme A (CoA), an essential metabolite for many important cellular processes (Brown et al., 1987). Pantothenate...

Overexpression, purification, and pharmacological activity of a biosynthetically derived conopeptide (2005)

Kumar, Ganesan Senthil, Ramasamy, Palanisamy, Sikdar, Sujit K, Sarma, Siddhartha P

A high yielding fusion protein system based on the protein cytochrome $b_{5}$ has been used for the production of novel 13-residue acyclic conopeptide. This peptide, Mo1659, can be liberated from the...

A novel approach for over-expression, characterization, and isotopic enrichment of a homogeneous species of acyl carrier protein from Plasmodium falciparum (2005)

Sharma, Shailendra Kumar, Modak, Rahul, Sharma, Shilpi, Sharma, Alok Kumar, Sarma, Siddhartha P, Surolia, Avadhesha, ...

Acyl carrier protein (ACP) plays a central role in fatty acid biosynthesis by transferring the acyl groups from one enzyme to another for the completion of the fatty acid synthesis cycle. Holo-ACP is...

High level expression of peptides and proteins using cytochrome $b_5$ as a fusion host (2005)

Mitra, Ashima, Chakrabarti, Kalyan Sundar, Hameed, Shahul MS, Srinivas, Kalyan V, Kumar, Ganesan Senthil, Sarma, Siddhartha P

A novel fusion protein system based on the highly soluble heme-binding domain of cytochrome $b_5$ has been designed. The ability of cytochrome $b_5$ to increase the levels of expression and...

A novel approach for over-expression, characterization, and isotopic enrichment of a homogeneous species of acyl carrier protein from Plasmodium falciparum (2005)

Sharma, Shailendra Kumar, Modak, Rahul, Sharma, Shilpi, Sharma, Alok Kumar, Sarma, Siddhartha P, Surolia, Avadhesha, ...

Acyl carrier protein (ACP) plays a central role in fatty acid biosynthesis by transferring the acyl groups from one enzyme to another for the completion of the fatty acid synthesis cycle. Holo-ACP is...

Overexpression, purification, and pharmacological activity of a biosynthetically derived conopeptide (2005)

Kumar, Ganesan Senthil, Ramasamy, Palanisamy, Sikdar, Sujit K, Sarma, Siddhartha P

A high yielding fusion protein system based on the protein cytochrome $b_{5}$ has been used for the production of novel 13-residue acyclic conopeptide. This peptide, Mo1659, can be liberated from the...

High level expression of peptides and proteins using cytochrome $b_5$ as a fusion host (2005)

Mitra, Ashima, Chakrabarti, Kalyan Sundar, Hameed, Shahul MS, Srinivas, Kalyan V, Kumar, Ganesan Senthil, Sarma, Siddhartha P

A novel fusion protein system based on the highly soluble heme-binding domain of cytochrome $b_5$ has been designed. The ability of cytochrome $b_5$ to increase the levels of expression and...

A novel 13 residue acyclic peptide from the marine snail, Conus monile, targets potassium channels (2004)

Sudarslal, Sadasivannair, Singaravadivelan, Govindaswamy, Ramasamy, Palanisamy, Ananda, Kuppanna, Sarma, Siddhartha P, Sikdar, Sujit K, ...

A novel 13-residue peptide Mo1659 has been isolated from the venom of a vermivorous cone snail, Conus monile. HPLC fractions of the venom extract yielded an intense UV absorbing fraction with a mass...

A novel 13 residue acyclic peptide from the marine snail, Conus monile, targets potassium channels (2004)

Sudarslal, Sadasivannair, Singaravadivelan, Govindaswamy, Ramasamy, Palanisamy, Ananda, Kuppanna, Sarma, Siddhartha P, Sikdar, Sujit K, ...

A novel 13-residue peptide Mo1659 has been isolated from the venom of a vermivorous cone snail, Conus monile. HPLC fractions of the venom extract yielded an intense UV absorbing fraction with a mass...

Sodium channel modulating activity in a delta-conotoxin from an Indian marine snail (2003)

Sudarslal, S, Majumdar, Sriparna, Ramasamy, P, Dhawan, Ritu, Pal, Prajna P, Ramaswami, Mani, ...

A 26 residue peptide (Am 2766) with the sequence CKQAGESCDIFSQNCCVG-TCAFICIE-NH2 has been isolated and purified from the venom of the molluscivorous snail, Conus amadis, collected off the...

Determination of Structures of Proteins in Solution using Nuclear Magnetic Resonance (2003)

Sarma, Siddhartha P

Nuclear magnetic resonance (NMR) is a manifestation of an intrinsic property of the nucleus, i.e. nuclear spin angular momentum. Spin angular momentum gives rise to magnetic moments. Thus, nuclei...

Sodium channel modulating activity in a delta-conotoxin from an Indian marine snail (2003)

Sudarslal, S, Majumdar, Sriparna, Ramasamy, P, Dhawan, Ritu, Pal, Prajna P, Ramaswami, Mani, ...

A 26 residue peptide (Am 2766) with the sequence CKQAGESCDIFSQNCCVG-TCAFICIE-NH2 has been isolated and purified from the venom of the molluscivorous snail, Conus amadis, collected off the...

Determination of Structures of Proteins in Solution using Nuclear Magnetic Resonance (2003)

Sarma, Siddhartha P

Nuclear magnetic resonance (NMR) is a manifestation of an intrinsic property of the nucleus, i.e. nuclear spin angular momentum. Spin angular momentum gives rise to magnetic moments. Thus, nuclei...

Structural consequences of replacement of an \alpha-helical Pro residue in Escherichia coli thioredoxin (2002)

Rudresh, *, Jain, Rinku, Dani, Vardhan, Mitra, Ashima, Srivastava, Sarika, Sarma, Siddhartha P, ...

While it is well known that introduction of Pro residues into the interior of protein $\alpha$-helices is destabilizing, there have been few studies that have examined the structural and...

Structural consequences of replacement of an \alpha-helical Pro residue in Escherichia coli thioredoxin (2002)

Rudresh, *, Jain, Rinku, Dani, Vardhan, Mitra, Ashima, Srivastava, Sarika, Sarma, Siddhartha P, ...

While it is well known that introduction of Pro residues into the interior of protein $\alpha$-helices is destabilizing, there have been few studies that have examined the structural and...