Jing Wang, Sijin Wen, W. Fraser Symmans, Lajos Pusztai, Kevin R. Coombes
Motivation: Identifying genes with bimodal expression patterns from large-scale expression profiling data is an important analytical task. Model-based clustering is popular for this purpose. That...
Tsavachidou, Dimitra, McDonnell, Timothy J., Wen, Sijin, Wang, Xuemei, Vakar-Lopez, Funda, Pisters, Louis L., ...
Background Secondary analyses of two randomized, controlled phase III trials demonstrated that selenium and vitamin E could reduce prostate cancer incidence. To characterize pharmacodynamic and gene...
Jing Wang, Kim Anh Do, Sijin Wen, Spyros Tsavachidis, Timothy J. Mcdonnell, Christopher J. Logothetis, ...
Merging microarray data, robust feature selection,
Thall, Peter F., Logothetis, Christopher, Pagliaro, Lance C., Wen, Sijin, Brown, Melissa A., Williams, Dallas, ...
Background Physicians typically switch therapies unless clinically relevant thresholds of response are observed, and treatments that produce high-quality responses and that are active in the salvage...
Correlation between CpG methylation profiles and hormone receptor status in breast cancers (2007)
Feng, Weiwei, Shen, Lanlan, Wen, Sijin, Rosen, Daniel G, Jelinek, Jaroslav, Hu, Xin, ...
Abstract Introduction Aberrant DNA methylation has been found frequently in human breast cancers, associated with the loss of expression of a number of regulatory genes for growth and correlated to...
Jing Wang, Kim Anh Do, Sijin Wen, Spyros Tsavachidis, Timothy J. McDonnell, Christopher J. Logothetis, ...
Motivation: Individual microarray studies searching for prognostic biomarkers often have few samples and low statistical power; however, publicly accessible data sets make it possible to combine data...
Jing Wang, Kim Anh Do, Sijin Wen, Spyros Tsavachidis, Timothy J. McDonnell, Christopher J. Logothetis, ...
Motivation: Individual microarray studies searching for prognostic biomarkers often have few samples and low statistical power; however, publicly accessible data sets make it possible to combine data...
Darren W. Davis, Yu Shen, Nizar A. Mullani, Sijin Wen, Roy S. Herbst, James L. Abbruzzese, ...
Purpose: In a recent study, we presented preliminary evidence for biological activity in a Phase I dose-finding study (15–600 mg/m 2) of recombinant human endostatin in patients with refractory...
Sharma, Padmanee, Shen, Yu, Wen, Sijin, Yamada, Sachiko, Jungbluth, Achim A., Gnjatic, Sacha, ...
Tumor-infiltrating cytotoxic T lymphocytes (TILs), including CD8 TILs, have been associated with favorable clinical outcomes in multiple tumor types. Tumor-infiltrating CD8 T cells and major...
Correlation between CpG methylation profiles and hormone receptor status in breast cancers
Feng, Weiwei, Shen, Lanlan, Wen, Sijin, Rosen, Daniel G, Jelinek, Jaroslav, Hu, Xin, ...