CYP450 polymorphisms as risk factors for early-onset lung cancer: gender-specific differences (2009)
Timofeeva, Maria N., Kropp, Silke, Sauter, Wiebke, Beckmann, Lars, Rosenberger, Albert, Illig, Thomas, ...
Cytochrome P450 (CYP) enzymes, involved in metabolism of tobacco carcinogens, are also involved in estrogen metabolism and many are regulated by estrogens. These genes may thus be of relevance to...
Vitamin D receptor gene polymorphisms and haplotypes and postmenopausal breast cancer risk (2008)
Abbas, Sascha, Nieters, Alexandra, Linseisen, Jakob, Slanger, Tracy, Kropp, Silke, Mutschelknauss, Elke, ...
Abstract Introduction Vitamin D receptor (VDR) genotypes may influence breast cancer risk by altering potential anticarcinogenic effects of vitamin D, but epidemiological studies have been...
Abbas, Sascha, Linseisen, Jakob, Slanger, Tracy, Kropp, Silke, Mutschelknauss, Elke Jonny, Flesch-Janys, Dieter, ...
Various studies suggest that vitamin D may reduce breast cancer risk. Most studies assessed the effects of dietary intake only, although endogenous production is an important source of vitamin D....
Association of a Common AKAP9 Variant With Breast Cancer Risk: A Collaborative Analysis (2008)
Frank, Bernd, Wiestler, Miriam, Kropp, Silke, Hemminki, Kari, Spurdle, Amanda B., Sutter, Christian, ...
Data from several studies have suggested that polymorphisms in A-kinase anchoring proteins (AKAPs), which are key components of signal transduction, contribute to carcinogenesis. To evaluate the...
Ambrosone, Christine B, Tian, Chunqiao, Ahn, Jiyoung, Kropp, Silke, Helmbold, Irmgard, Von Fournier, Dietrich, ...
Abstract Introduction The cytotoxic effects of radiation therapy are mediated primarily through increased formation of hydroxyl radicals and reactive oxygen species, which can damage cells, proteins...
Lilla, Carmen, Risch, Angela, Kropp, Silke, Chang-Claude, Jenny
Abstract Introduction Sulfotransferase 1A1 (encoded by SULT1A1 ) is involved in the metabolism of procarcinogens such as heterocyclic amines and polycyclic aromatic hydrocarbons, both of which are...
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Steindorf, Karen, Schmidt, Martina, Kropp, Silke, Chang-Claude, Jenny
Important aspects of the recognized inverse relation between physical activity and breast cancer risk are still under discussion. Data on physical activity from sports, occupational activity,...
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Active and Passive Smoking and Risk of Breast Cancer by Age 50 Years among German Women (2002)
Kropp, Silke, Chang-Claude, Jenny
Recent studies suggest that both active and passive smokers have an increased risk of breast cancer compared with women who have never been either actively or passively exposed. Data on lifetime...
Heidelberg, Univ., Diss., 2001.
Kropp, Silke, Becher, Heiko, Nieters, Alexandra, Chang-Claude, Jenny
Studies of the association between alcohol drinking and breast cancer show a tendency towards an increase in risk for high consumption levels but yield less consistent results for low-to-moderate...
Ambrosone, Christine B, Tian, Chunqiao, Ahn, Jiyoung, Kropp, Silke, Helmbold, Irmgard, Von Fournier, Dietrich, ...
Garcia-Closas, Montserrat, Hall, Per, Nevanlinna, Heli, Pooley, Karen, Morrison, Jonathan, Richesson, Douglas A., ...
A three-stage genome-wide association study recently identified single nucleotide polymorphisms (SNPs) in five loci (fibroblast growth receptor 2 (FGFR2), trinucleotide repeat containing 9 (TNRC9),...