Silvia Buonamici

EVI1 induces myelodysplastic syndrome in mice

Buonamici, Silvia, Li, Donglan, Chi, Yiqing, Zhao, Rui, Wang, Xuerong, Brace, Larry, ...

Myelodysplasia is a hematological disease in which genomic abnormalities accumulate in a hematopoietic stem cell leading to severe pancytopenia, multilineage differentiation impairment, and bone...

EVI1 induces myelodysplastic syndrome in mice

Buonamici, Silvia, Li, Donglan, Chi, Yiqing, Zhao, Rui, Wang, Xuerong, Brace, Larry, ...

Myelodysplasia is a hematological disease in which genomic abnormalities accumulate in a hematopoietic stem cell leading to severe pancytopenia, multilineage differentiation impairment, and bone...

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

Thompson, Benjamin J., Buonamici, Silvia, Sulis, Maria Luisa, Palomero, Teresa, Vilimas, Tomas, Basso, Giuseppe, ...

Recent studies have shown that activating mutations of NOTCH1 are responsible for the majority of T cell acute lymphoblastic leukemia (T-ALL) cases. Most of these mutations truncate its C-terminal...