Marsella, Luca, Sirocco, Francesco, Trovato, Antonio, Seno, Flavio, Tosatto, Silvio C.E.
Motivation: Proteins with solenoid repeats evolve more quickly than non-repetitive ones and their periodicity may be rapidly hidden at sequence level, while still evident in structure. In order to...
TESE: generating specific protein structure test set ensembles (2008)
Sirocco, Francesco, Tosatto, Silvio C. E.
Summary: TESE is a web server for the generation of test sets of protein sequences and structures fulfilling a number of different criteria. At least three different use cases can be envisaged: (i)...
The PASTA server for protein aggregation prediction (2007)
Trovato, Antonio, Seno, Flavio, Tosatto, Silvio C.E.
Many different proteins aggregate into amyloid fibrils characterized by cross-β structure. β-strands contributed by distinct protein molecules are generally found in a parallel in-register...
Vullo, Alessandro, Bortolami, Oscar, Pollastri, Gianluca, Tosatto, Silvio C. E.
Intrinsically disordered proteins have long stretches of their polypeptide chain, which do not adopt a single native structure composed of stable secondary and tertiary structure in the absence of...
Decomposing protein networks into domain-domain interactions (2005)
Albrecht, Mario, Huthmacher, Carola, Tosatto, Silvio C.E., Lengauer, Thomas
Fogolari, Federico, Tosatto, Silvio C.E.
Accurate free energy estimation is needed in many predictive tasks. The molecular mechanics/Poisson-Boltzmann solvent accessible surface area (MM/PBSA) approach has proven to be accurate. However,...
The SSEA server for protein secondary structure alignment (2005)
Fontana, Paolo, Bindewald, Eckart, Toppo, Stefano, Velasco, Riccardo, Valle, Giorgio, Tosatto, Silvio C. E.
Summary: We present a web server that computes alignments of protein secondary structures. The server supports both performing pairwise alignments and searching a secondary structure against a...
Decomposing protein networks into domain-domain interactions (2005)
Albrecht, Mario, Huthmacher, Carola, Tosatto, Silvio C. E., Lengauer, Thomas
Summary: The application of novel experimental techniques has generated large networks of protein–protein interactions. Frequently, important information on the structure and cellular function of...
The SSEA server for protein secondary structure alignment (2004)
Fontana, Paolo, Bindewald, Eckart, Toppo, Stefano, Velasco, Riccardo, Valle, Giorgio, Tosatto, Silvio C. E.
Summary: We present a web server which computes alignments of protein secondary structures. The server supports both performing pairwise alignments and searching a secondary structure against a...
The SSEA server for protein secondary structure alignment (2004)
Fontana, Paolo, Bindewald, Eckart, Toppo, Stefano, Velasco, Riccardo, Valle, Giorgio, Tosatto, Silvio C. E.
Summary: We present a web server which computes alignments of protein secondary structures. The server supports both performing pairwise alignments and searching a secondary structure against a...
Simple consensus procedures are effective and sufficient in secondary structure prediction (2003)
Albrecht,Mario, Tosatto,Silvio C.E., Lengauer,Thomas, Valle,Giorgio
Simple consensus procedures are effective and sufficient in secondary structure prediction (2003)
Albrecht, Mario, Tosatto, Silvio C.E., Lengauer, Thomas, Valle, Giorgio
Simple consensus procedures are effective and sufficient in secondary structure prediction (2003)
Albrecht, Mario, Tosatto, Silvio C.E., Lengauer, Thomas, Valle, Giorgio
We have analyzed the performance of majority voting on minimal combination sets of three state‐of‐the‐art secondary structure prediction methods in order to obtain a consensus...
A divide and conquer approach to fast loop modeling (2002)
Tosatto, Silvio C.E., Bindewald, Eckart, Hesser, Jürgen, Männer, Reinhard
We describe a fast ab initio method for modeling local segments in protein structures. The algorithm is based on a divide and conquer approach and uses a database of precalculated look-up tables,...
Vullo, Alessandro, Bortolami, Oscar, Pollastri, Gianluca, Tosatto, Silvio C. E.
Intrinsically disordered proteins have long stretches of their polypeptide chain, which do not adopt a single native structure composed of stable secondary and tertiary structure in the absence of...
Vullo, Alessandro, Bortolami, Oscar, Pollastri, Gianluca, Tosatto, Silvio C. E.
Intrinsically disordered proteins have long stretches of their polypeptide chain, which do not adopt a single native structure composed of stable secondary and tertiary structure in the absence of...
Fogolari, Federico, Tosatto, Silvio C.E.
Accurate free energy estimation is needed in many predictive tasks. The molecular mechanics/Poisson-Boltzmann solvent accessible surface area (MM/PBSA) approach has proven to be accurate. However,...
Marsella, Luca, Sirocco, Francesco, Trovato, Antonio, Seno, Flavio, Tosatto, Silvio C.E.
Motivation: Proteins with solenoid repeats evolve more quickly than non-repetitive ones and their periodicity may be rapidly hidden at sequence level, while still evident in structure. In order to...