Simina Boca

DESIGN AND ANALYSIS ISSUES IN GENOME-WIDE SOMATIC MUTATION STUDIES OF CANCER (2008)

Parmigiani, Giovanni, Boca, Simina, Lin, Jimmy, Kinzler, Kenneth W., Velculescu, Victor E., Vogelstein, Bert

The availability of the human genome sequence and progress in sequencing and bioinformatic technologies have enabled genome-wide investigation of somatic mu- tations in human cancers. This article...

DESIGN AND ANALYSIS ISSUES IN GENOME-WIDE SOMATIC MUTATION STUDIES OF CANCER (2008)

Parmigiani, Giovanni, Boca, Simina, Lin, Jimmy, Kinzler, Kenneth W., Velculescu, Victor E., Vogelstein, Bert

The availability of the human genome sequence and progress in sequencing and bioinformatic technologies have enabled genome-wide investigation of somatic mu- tations in human cancers. This article...

DESIGN AND ANALYSIS ISSUES IN GENOME-WIDE SOMATIC MUTATION STUDIES OF CANCER (2008)

Parmigiani, Giovanni, Boca, Simina, Lin, Jimmy, Kinzler, Kenneth W., Velculescu, Victor E., Vogelstein, Bert

The availability of the human genome sequence and progress in sequencing and bioinformatic technologies have enabled genome-wide investigation of somatic mu- tations in human cancers. This article...

DESIGN AND ANALYSIS ISSUES IN GENOME-WIDE SOMATIC MUTATION STUDIES OF CANCER (2008)

Parmigiani, Giovanni, Boca, Simina, Lin, Jimmy, Kinzler, Kenneth W., Velculescu, Victor E., Vogelstein, Bert

The availability of the human genome sequence and progress in sequencing and bioinformatic technologies have enabled genome-wide investigation of somatic mu- tations in human cancers. This article...

Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers. (2008)

Leary, Rebecca J., Lin, Jimmy C., Cummins, Jordan, Boca, Simina, Wood, Laura D., Parsons, D. Williams, ...

We have performed a genome-wide analysis of copy number changes in breast and colorectal tumors using approaches that can reliably detect homozygous deletions and amplifications. We found that the...

STATISTICAL METHODS FOR THE ANALYSIS OF CANCER GENOME SEQUENCING DATA (2007)

Parmigiani, Giovanni, Lin, J., Boca, Simina, Sjoblom, T., Kinzler, K.W., Velculescu, V.E., ...

The purpose of cancer genome sequencing studies is to determine the nature and types of alterations present in a typical cancer and to discover genes mutated at high frequencies. In this article we...

STATISTICAL METHODS FOR THE ANALYSIS OF CANCER GENOME SEQUENCING DATA (2007)

Parmigiani, Giovanni, Lin, J., Boca, Simina, Sjoblom, T., Kinzler, K.W., Velculescu, V.E., ...

The purpose of cancer genome sequencing studies is to determine the nature and types of alterations present in a typical cancer and to discover genes mutated at high frequencies. In this article we...

STATISTICAL METHODS FOR THE ANALYSIS OF CANCER GENOME SEQUENCING DATA (2007)

Parmigiani, Giovanni, Lin, J., Boca, Simina, Sjoblom, T., Kinzler, K.W., Velculescu, V.E., ...

The purpose of cancer genome sequencing studies is to determine the nature and types of alterations present in a typical cancer and to discover genes mutated at high frequencies. In this article we...

STATISTICAL METHODS FOR THE ANALYSIS OF CANCER GENOME SEQUENCING DATA (2007)

Parmigiani, Giovanni, Lin, J., Boca, Simina, Sjoblom, T., Kinzler, K.W., Velculescu, V.E., ...

The purpose of cancer genome sequencing studies is to determine the nature and types of alterations present in a typical cancer and to discover genes mutated at high frequencies. In this article we...

Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers

Leary, Rebecca J., Lin, Jimmy C., Cummins, Jordan, Boca, Simina, Wood, Laura D., Parsons, D. Williams, ...

We have performed a genome-wide analysis of copy number changes in breast and colorectal tumors using approaches that can reliably detect homozygous deletions and amplifications. We found that the...