Simon J. Elliott

The Cloned Locus of Enterocyte Effacement from Enterohemorrhagic Escherichia coli O157:H7 Is Unable To Confer the Attaching and Effacing Phenotype upon E. coli K-12

Elliott, Simon J., Yu, Jie, Kaper, James B.

The locus of enterocyte effacement (LEE) pathogenicity island of enterohemorrhagic Escherichia coli (EHEC) O157:H7 possesses the same genes in identical order and orientation as the LEE of...

The Locus of Enterocyte Effacement (LEE)-Encoded Regulator Controls Expression of Both LEE- and Non-LEE-Encoded Virulence Factors in Enteropathogenic and Enterohemorrhagic Escherichia coli

Elliott, Simon J., Sperandio, Vanessa, Girón, Jorge A., Shin, Sooan, Mellies, Jay L., Wainwright, Leslie, ...

Regulation of virulence gene expression in enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC) is incompletely understood. In EPEC, the plasmid-encoded regulator Per is...

Complete Nucleotide Sequence and Analysis of the Locus of Enterocyte Effacement from Rabbit Diarrheagenic Escherichia coli RDEC-1

Zhu, Chengru, Agin, Tonia S., Elliott, Simon J., Johnson, Laura A., Thate, Timothy E., Kaper, James B., ...

The pathogenicity island termed the locus of enterocyte effacement (LEE) is found in diverse attaching and effacing pathogens associated with diarrhea in humans and other animal species. To explore...

EspG, a Novel Type III System-Secreted Protein from Enteropathogenic Escherichia coli with Similarities to VirA of Shigella flexneri

Elliott, Simon J., Krejany, Efrosinia O., Mellies, Jay L., Robins-Browne, Roy M., Sasakawa, Chihiro, Kaper, James B.

The function of the rorf2 gene located on the locus of enterocyte effacement (LEE) pathogenicity island of enteropathogenic Escherichia coli (EPEC) has not been described. We report that rorf2...

Characterization of the Roles of Hemolysin and Other Toxins in Enteropathy Caused by Alpha-Hemolytic Escherichia coli Linked to Human Diarrhea

Elliott, Simon J., Srinivas, S., Albert, M. John, Alam, Khorshed, Robins-Browne, Roy M., Gunzburg, Stuart T., ...

Escherichia coli strains producing alpha-hemolysin have been associated with diarrhea in several studies, but it has not been clearly demonstrated that these strains are enteropathogens or that...

Antibiotic-Resistant Cell-Detaching Escherichia coli Strains from Nigerian Children

Okeke, Iruka N., Steinrück, Hartmut, Kanack, Kristen J., Elliott, Simon J., Sundström, Lars, Kaper, James B., ...

The properties of 23 cell-detaching Escherichia coli strains that were isolated from stool specimens in Nigeria are described. Common properties of the strains included the presence of genes encoding...

A Gene from the Locus of Enterocyte Effacement That Is Required for Enteropathogenic Escherichia coli To Increase Tight-Junction Permeability Encodes a Chaperone for EspF

Elliott, Simon J., O'Connell, Colin B., Koutsouris, Athanasia, Brinkley, Carl, Donnenberg, Michael S., Hecht, Gail, ...

Disruption of the barrier properties of the enterocyte tight junction is believed to be important in the pathogenesis of diarrhea caused by enteropathogenic Escherichia coli (EPEC). This phenotype...

The Cloned Locus of Enterocyte Effacement from Enterohemorrhagic Escherichia coli O157:H7 Is Unable To Confer the Attaching and Effacing Phenotype upon E. coli K-12

Elliott, Simon J., Yu, Jie, Kaper, James B.

The locus of enterocyte effacement (LEE) pathogenicity island of enterohemorrhagic Escherichia coli (EHEC) O157:H7 possesses the same genes in identical order and orientation as the LEE of...

The Locus of Enterocyte Effacement (LEE)-Encoded Regulator Controls Expression of Both LEE- and Non-LEE-Encoded Virulence Factors in Enteropathogenic and Enterohemorrhagic Escherichia coli

Elliott, Simon J., Sperandio, Vanessa, Girón, Jorge A., Shin, Sooan, Mellies, Jay L., Wainwright, Leslie, ...

Regulation of virulence gene expression in enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC) is incompletely understood. In EPEC, the plasmid-encoded regulator Per is...

Complete Nucleotide Sequence and Analysis of the Locus of Enterocyte Effacement from Rabbit Diarrheagenic Escherichia coli RDEC-1

Zhu, Chengru, Agin, Tonia S., Elliott, Simon J., Johnson, Laura A., Thate, Timothy E., Kaper, James B., ...

The pathogenicity island termed the locus of enterocyte effacement (LEE) is found in diverse attaching and effacing pathogens associated with diarrhea in humans and other animal species. To explore...

EspG, a Novel Type III System-Secreted Protein from Enteropathogenic Escherichia coli with Similarities to VirA of Shigella flexneri

Elliott, Simon J., Krejany, Efrosinia O., Mellies, Jay L., Robins-Browne, Roy M., Sasakawa, Chihiro, Kaper, James B.

The function of the rorf2 gene located on the locus of enterocyte effacement (LEE) pathogenicity island of enteropathogenic Escherichia coli (EPEC) has not been described. We report that rorf2...

Characterization of the Roles of Hemolysin and Other Toxins in Enteropathy Caused by Alpha-Hemolytic Escherichia coli Linked to Human Diarrhea

Elliott, Simon J., Srinivas, S., Albert, M. John, Alam, Khorshed, Robins-Browne, Roy M., Gunzburg, Stuart T., ...

Escherichia coli strains producing alpha-hemolysin have been associated with diarrhea in several studies, but it has not been clearly demonstrated that these strains are enteropathogens or that...

Antibiotic-Resistant Cell-Detaching Escherichia coli Strains from Nigerian Children

Okeke, Iruka N., Steinrück, Hartmut, Kanack, Kristen J., Elliott, Simon J., Sundström, Lars, Kaper, James B., ...

The properties of 23 cell-detaching Escherichia coli strains that were isolated from stool specimens in Nigeria are described. Common properties of the strains included the presence of genes encoding...

A Gene from the Locus of Enterocyte Effacement That Is Required for Enteropathogenic Escherichia coli To Increase Tight-Junction Permeability Encodes a Chaperone for EspF

Elliott, Simon J., O'Connell, Colin B., Koutsouris, Athanasia, Brinkley, Carl, Donnenberg, Michael S., Hecht, Gail, ...

Disruption of the barrier properties of the enterocyte tight junction is believed to be important in the pathogenesis of diarrhea caused by enteropathogenic Escherichia coli (EPEC). This phenotype...