Simoy Goldstein

Comparative Efficacy of Recombinant Modified Vaccinia Virus Ankara Expressing Simian Immunodeficiency Virus (SIV) Gag-Pol and/or Env in Macaques Challenged with Pathogenic SIV

Ourmanov, Ilnour, Brown, Charles R., Moss, Bernard, Carroll, Miles, Wyatt, Linda, Pletneva, Liuobov, ...

Prior studies demonstrated that immunization of macaques with simian immunodeficiency virus (SIV) Gag-Pol and Env recombinants of the attenuated poxvirus modified vaccinia virus Ankara (MVA) provided...

Intrinsic Susceptibility of Rhesus Macaque Peripheral CD4+ T Cells to Simian Immunodeficiency Virus In Vitro Is Predictive of In Vivo Viral Replication

Goldstein, Simoy, Brown, Charles R., Dehghani, Houman, Lifson, Jeffrey D., Hirsch, Vanessa M.

Previous studies with simian immunodeficiency virus (SIV) infection of rhesus macaques suggested that the intrinsic susceptibility of peripheral blood mononuclear cells (PBMC) to infection with SIV...

Wide Range of Viral Load in Healthy African Green Monkeys Naturally Infected with Simian Immunodeficiency Virus

Goldstein, Simoy, Ourmanov, Ilnour, Brown, Charles R., Beer, Brigitte E., Elkins, William R., Plishka, Ronald, ...

The distribution and levels of simian immunodeficiency virus (SIV) in tissues and plasma were assessed in naturally infected African green monkeys (AGM) of the vervet subspecies (Chlorocebus...

Immune Failure in the Absence of Profound CD4+ T-Lymphocyte Depletion in Simian Immunodeficiency Virus-Infected Rapid Progressor Macaques

Hirsch, Vanessa M., Santra, Sampa, Goldstein, Simoy, Plishka, Ronald, Buckler-White, Alicia, Seth, Aruna, ...

A fraction of simian immunodeficiency virus (SIV)-infected macaques develop rapidly progressive disease in the apparent absence of detectable SIV-specific antibody responses. To characterize the...

Highly pathogenic SHIVs and SIVs target different CD4+ T cell subsets in rhesus monkeys, explaining their divergent clinical courses

Nishimura, Yoshiaki, Igarashi, Tatsuhiko, Donau, Olivia K., Buckler-White, Alicia, Buckler, Charles, Lafont, Bernard A. P., ...

In contrast to simian immunodeficiency viruses (SIVs), which induce immunodeficiency over a 1- to 3-year period, highly pathogenic simian-human immunodeficiency viruses (SHIVs) cause a complete,...

Plateau Levels of Viremia Correlate with the Degree of CD4+-T-Cell Loss in Simian Immunodeficiency Virus SIVagm-Infected Pigtailed Macaques: Variable Pathogenicity of Natural SIVagm Isolates

Goldstein, Simoy, Ourmanov, Ilnour, Brown, Charles R., Plishka, Ronald, Buckler-White, Alicia, Byrum, Russell, ...

Simian immunodeficiency virus from African green monkeys (SIVagm) results in asymptomatic infection in its natural host species. The virus is not inherently apathogenic, since infection of pigtailed...

Immunodeficiency in the Absence of High Viral Load in Pig-Tailed Macaques Infected with Simian Immunodeficiency Virus SIVsun or SIVlhoest

Beer, Brigitte E., Brown, Charles R., Whitted, Sonya, Goldstein, Simoy, Goeken, Robert, Plishka, Ronald, ...

Simian immunodeficiency virus (SIV) is known to result in an asymptomatic infection of its natural African monkey host. However, some SIV strains are capable of inducing AIDS-like symptoms and death...

Comparison of Simian Immunodeficiency Virus SIVagmVer Replication and CD4+ T-Cell Dynamics in Vervet and Sabaeus African Green Monkeys

Goldstein, Simoy, Brown, Charles R., Ourmanov, Ilnour, Pandrea, Ivona, Buckler-White, Alicia, Erb, Christopher, ...

The simian immunodeficiency viruses (SIV) naturally infect a wide range of African primates, including African green monkeys (AGM). Despite moderate to high levels of plasma viremia in naturally...

Comparative Efficacy of Recombinant Modified Vaccinia Virus Ankara Expressing Simian Immunodeficiency Virus (SIV) Gag-Pol and/or Env in Macaques Challenged with Pathogenic SIV

Ourmanov, Ilnour, Brown, Charles R., Moss, Bernard, Carroll, Miles, Wyatt, Linda, Pletneva, Liuobov, ...

Prior studies demonstrated that immunization of macaques with simian immunodeficiency virus (SIV) Gag-Pol and Env recombinants of the attenuated poxvirus modified vaccinia virus Ankara (MVA) provided...

Intrinsic Susceptibility of Rhesus Macaque Peripheral CD4+ T Cells to Simian Immunodeficiency Virus In Vitro Is Predictive of In Vivo Viral Replication

Goldstein, Simoy, Brown, Charles R., Dehghani, Houman, Lifson, Jeffrey D., Hirsch, Vanessa M.

Previous studies with simian immunodeficiency virus (SIV) infection of rhesus macaques suggested that the intrinsic susceptibility of peripheral blood mononuclear cells (PBMC) to infection with SIV...

Wide Range of Viral Load in Healthy African Green Monkeys Naturally Infected with Simian Immunodeficiency Virus

Goldstein, Simoy, Ourmanov, Ilnour, Brown, Charles R., Beer, Brigitte E., Elkins, William R., Plishka, Ronald, ...

The distribution and levels of simian immunodeficiency virus (SIV) in tissues and plasma were assessed in naturally infected African green monkeys (AGM) of the vervet subspecies (Chlorocebus...

Immune Failure in the Absence of Profound CD4+ T-Lymphocyte Depletion in Simian Immunodeficiency Virus-Infected Rapid Progressor Macaques

Hirsch, Vanessa M., Santra, Sampa, Goldstein, Simoy, Plishka, Ronald, Buckler-White, Alicia, Seth, Aruna, ...

A fraction of simian immunodeficiency virus (SIV)-infected macaques develop rapidly progressive disease in the apparent absence of detectable SIV-specific antibody responses. To characterize the...

Highly pathogenic SHIVs and SIVs target different CD4+ T cell subsets in rhesus monkeys, explaining their divergent clinical courses

Nishimura, Yoshiaki, Igarashi, Tatsuhiko, Donau, Olivia K., Buckler-White, Alicia, Buckler, Charles, Lafont, Bernard A. P., ...

In contrast to simian immunodeficiency viruses (SIVs), which induce immunodeficiency over a 1- to 3-year period, highly pathogenic simian-human immunodeficiency viruses (SHIVs) cause a complete,...

Plateau Levels of Viremia Correlate with the Degree of CD4+-T-Cell Loss in Simian Immunodeficiency Virus SIVagm-Infected Pigtailed Macaques: Variable Pathogenicity of Natural SIVagm Isolates

Goldstein, Simoy, Ourmanov, Ilnour, Brown, Charles R., Plishka, Ronald, Buckler-White, Alicia, Byrum, Russell, ...

Simian immunodeficiency virus from African green monkeys (SIVagm) results in asymptomatic infection in its natural host species. The virus is not inherently apathogenic, since infection of pigtailed...

Immunodeficiency in the Absence of High Viral Load in Pig-Tailed Macaques Infected with Simian Immunodeficiency Virus SIVsun or SIVlhoest

Beer, Brigitte E., Brown, Charles R., Whitted, Sonya, Goldstein, Simoy, Goeken, Robert, Plishka, Ronald, ...

Simian immunodeficiency virus (SIV) is known to result in an asymptomatic infection of its natural African monkey host. However, some SIV strains are capable of inducing AIDS-like symptoms and death...

Comparison of Simian Immunodeficiency Virus SIVagmVer Replication and CD4+ T-Cell Dynamics in Vervet and Sabaeus African Green Monkeys

Goldstein, Simoy, Brown, Charles R., Ourmanov, Ilnour, Pandrea, Ivona, Buckler-White, Alicia, Erb, Christopher, ...

The simian immunodeficiency viruses (SIV) naturally infect a wide range of African primates, including African green monkeys (AGM). Despite moderate to high levels of plasma viremia in naturally...