Miggin, Sinead M., Pålsson-McDermott, Eva, Dunne, Aisling, Jefferies, Caroline, Pinteaux, Emmanuel, Banahan, Kathy, ...
Toll-like receptors (TLRs)-2 and -4 are important proteins in innate immunity, recognizing microbial products and eliciting host defense responses. Both use the adapter proteins MyD88 and MyD88...
The effects of the statins lovastatin and cerivastatin on signalling by the prostanoid IP-receptor
Lawler, Orlaith A, Miggin, Sinead M, Kinsella, B Therese
The prostanoid-IP receptor may be unique among G protein coupled receptors in that it is isoprenylated. In this study, we investigated the effects of the statins lovastatin and cerivastatin on...