Heteroduplex Formation in SMN Gene Dosage Analysis
Ogino, Shuji, Leonard, Debra G. B., Rennert, Hanna, Gao, Sizhen, Wilson, Robert B.
Most spinal muscular atrophy patients lack both copies of SMN1 exon 7 and most carriers have only one copy of SMN1 exon 7. We investigated the effect of SMN1/SMN2 heteroduplex formation on SMN gene...
Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival
Fung, Christopher, Lock, Rebecca, Gao, Sizhen, Salas, Eduardo, Debnath, Jayanta
Autophagy has been proposed to promote cell death during lumen formation in three-dimensional mammary epithelial acini because numerous autophagic vacuoles are observed in the dying central cells...