Sofia Gruvberger-Saal

Exploring the two-gene ratio in breast cancer – independent roles for HOXB13 and IL17BR in prediction of clinical outcome (2008)

Jerevall, Piiha-Lotta, Brommesson, Sara, Strand, Carina, Gruvberger-Saal, Sofia, Malmström, Per, Nordenskjöld, Bo, ...

Background: The two-gene expression ratio HOXB13:IL17BR has been proposed to predict the outcome of tamoxifen-treated breast cancer patients. We intended to examine whether this ratio can predict the...

Basal-like phenotype is not associated with patient survival in estrogen-receptor-negative breast cancers (2007)

Jumppanen, Mervi, Gruvberger-Saal, Sofia, Kauraniemi, Päivikki, Tanner, Minna, Bendahl, Pär-Ola, Lundin, Mikael, ...

Abstract Introduction Basal-phenotype or basal-like breast cancers are characterized by basal epithelium cytokeratin (CK5/14/17) expression, negative estrogen receptor (ER) status and distinct gene...

Basal-like phenotype is not associated with patient survival in estrogen-receptor-negative breast cancers

Jumppanen, Mervi, Gruvberger-Saal, Sofia, Kauraniemi, Päivikki, Tanner, Minna, Bendahl, Pär-Ola, Lundin, Mikael, ...

Irs2 Inactivation Suppresses Tumor Progression in Pten+/− Mice

Szabolcs, Matthias, Keniry, Megan, Simpson, Laura, Reid, Latarsha J., Koujak, Susan, Schiff, Sarah C., ...

Mutations in the phosphatase and tensin homologue (PTEN)/phosphatidylinositol-3 kinase-α (PI3K) signaling pathway are frequently found in human cancer. In addition, Pten+/− mice develop tumors in...