Los inicios de los antihistamínicos (2008)
Hace casi cien años que Sir Henry Dale y sus colaboradores en los laboratorios Wellcome aislaron la histamina a partir del cornezuelo del centeno. Inmediatamente después, se embarcaron en un...
Fiber-Type-Specific Transcription of the Troponin I Slow Gene Is Regulated by Multiple Elements
Calvo, Soledad, Venepally, Pratap, Cheng, Jun, Buonanno, Andres
The regulatory elements that restrict transcription of genes encoding contractile proteins specifically to either slow- or fast-twitch skeletal muscles are unknown. As an initial step towards...
Molecular Dissection of DNA Sequences and Factors Involved in Slow Muscle-Specific Transcription
Calvo, Soledad, Vullhorst, Detlef, Venepally, Pratap, Cheng, Jun, Karavanova, Irina, Buonanno, Andres
Transcription is a major regulatory mechanism for the generation of slow- and fast-twitch myofibers. We previously identified an upstream region of the slow TnI gene (slow upstream regulatory element...
Fiber-Type-Specific Transcription of the Troponin I Slow Gene Is Regulated by Multiple Elements
Calvo, Soledad, Venepally, Pratap, Cheng, Jun, Buonanno, Andres
The regulatory elements that restrict transcription of genes encoding contractile proteins specifically to either slow- or fast-twitch skeletal muscles are unknown. As an initial step towards...
Molecular Dissection of DNA Sequences and Factors Involved in Slow Muscle-Specific Transcription
Calvo, Soledad, Vullhorst, Detlef, Venepally, Pratap, Cheng, Jun, Karavanova, Irina, Buonanno, Andres
Transcription is a major regulatory mechanism for the generation of slow- and fast-twitch myofibers. We previously identified an upstream region of the slow TnI gene (slow upstream regulatory element...
Veratridine induces apoptotic death in bovine chromaffin cells through superoxide production
Jordán, Joaquín, Galindo, María F, Calvo, Soledad, González-García, Carmen, Ceña, Valentín
The molecular mechanisms involved in veratridine-induced chromaffin cell death have been explored.We have found that exposure to veratridine (30 μM, 1 h) produces a delayed cellular death that...