The prevalence of BRCA1 mutations among young women with triple-negative breast cancer (2009)
Young, SR, Pilarski, Robert T, Donenberg, Talia, Shapiro, Charles, Hammond, Lyn S, Miller, Judith, ...
Abstract Background Molecular screening for BRCA1 and BRCA2 mutations is now an established component of risk evaluation and management of familial breast cancer. Features of hereditary breast cancer...
Xinhua He, Wu Zhong, Junhai Xiao, Zhibing Zheng, Song Li
In the title compound, C23H17Cl3N4O, the benzene rings are oriented with respect to the pyrazole ring at dihedral angles of 39.9 (2) and 72.90 (13)° for the chlorophenyl and...
Karyotype evolution of shrew moles (Soricomorpha: Talpidae) (2008)
Shin-ichiro Kawada, Song Li, Ying-xiang Wang, Orin B. Mock, Sen-ichi Oda, Kevin L. Campbell
The Chinese long-tailed mole (Scaptonyx fusicaudus) closely resembles American (Neurotrichus gibbsii) and Japanese (Dymecodon pilirostris and Urotrichus talpoides) shrew moles in size, appearance,...
Boolean network simulations for life scientists (2008)
Albert, István, Thakar, Juilee, Li, Song, Zhang, Ranran, Albert, Réka
Abstract Modern life sciences research increasingly relies on computational solutions, from large scale data analyses to theoretical modeling. Within the theoretical models Boolean networks occupy an...
A New Species of Paramesotriton - Paramesotriton longliensis (Caudata: Salamandridae) (2008)
LI, Song, TIAN, Ying-zhou, GU, Xiao-ming, XIONG, Rong-chuan
A new species of Paramesotriton longliensis sp.nov. (Holotype: No.0705015, adult male; Allotype: No.0705019, adult female; Paratypes: 10♂♂, 10♀♀) was discovered during a survey of...
Dynamical Evolution of Interacting Modified Chaplygin Gas (2008)
Li, Song, Ma, Yongge, Chen, Yun
The cosmological model of modified Chaplygin gas interacting with a barotropic fluid is studied. Our attention is focused on the final state of universe in the model. It turns out that there exists a...
subunit derived by homology modeling (2008)
Dong Yan, Yuan-dong Hu, Song Li, Mao-sheng Cheng
KEY WORDS peptic ulcer; H(+)-K(+)-exchanging ATPase; protein structural homology; drug design AIM: To build a model of 3D-structure of H +, K +-ATPase catalytic subunit for theoretical study and...
Qing Feng, Song Li, Yingxiang Wang
Bamboo bats are a group of small bats with unique skull and morphology. They roost inside hollow bamboo stems in tropical and subtropical Asia and the Ambon Islands (Moluccas). We examined 53...
HIGH RESOLUTION MID-INFRARED SPECTROSCOPY OF D$_2$O$^{+}$ (2008)
Duan, Chuanxi, Zheng, Rui, Li, Song, Huang, Guangming
Author Institution: College of Physical Science and Technology, HuaZhong; Normal University, Wuhan 430079, China
catena-Poly[[tris(pyridine-κN)copper(II)]-μ-tetrafluoroterephthalato-κ2O1:O4] (2008)
Chang-Ge Zheng, Jie Zhang, Jian-Quan Hong, Song Li
In the title compound, [Cu(C8F4O4)(C5H5N)3]n, the CuII atom, lying on a twofold rotation axis, is five-coordinated by two O atoms from two tetrafluoroterephthalate ligands and three N atoms from...
catena-Poly[[tris(pyridine-κN)copper(II)]-μ-tetrafluoroterephthalato-κ2O1:O4] (2008)
Chang-Ge Zheng, Jie Zhang, Jian-Quan Hong, Song Li
In the title compound, [Cu(C8F4O4)(C5H5N)3]n, the CuII atom, lying on a twofold rotation axis, is five-coordinated by two O atoms from two tetrafluoroterephthalate ligands and three N atoms from...
FXR-mediated regulation of eNOS expression in vascular endothelial cells (2008)
Li, Jiang, Wilson, Annette, Kuruba, Ramalinga, Zhang, Qiuhong, Gao, Xiang, He, Fengtian, ...
Aims The farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily that is highly expressed in liver, kidney, adrenals, and intestine. FXR was previously proposed to play an...
Zhang, Qiuhong, He, Fengtian, Kuruba, Ramalinga, Gao, Xiang, Wilson, Annette, Li, Jiang, ...
Aims The farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily and plays an important role in the pathogenesis of cardiovascular diseases via regulating the metabolism and...
An Object-Oriented Toolkit for (2007)
Constructing Virtual Reality, Russell Turner, Song Li, Enrico Gobbetti
: Virtual reality systems provide realistic look and feel by seamlessly integrating three-dimensional input and output devices. One software architecture approach to constructing such systems is to...
Covert Channels and Anonymous Communication in Ad-hoc Networks (2007)
Ad-hoc wireless networks distinguish themselves from their traditional wired counterparts by three unique characteristics: mobility, lack of infrastructure, and shared wireless channel. These...
Covert Channels and Anonymous Communication in Ad-hoc Networks (2007)
Ad-hoc wireless networks distinguish themselves from their traditional wired counterparts by three unique characteristics: mobility, lack of infrastructure, and shared wireless channel. These...
Patel, Shyam, Kurpinski, Kyle, Quigley, Ryan, Gao, Hongfeng, Hsiao, Benjamin S., Poo, Mu-Ming, ...
Biodegradable nanofibers have tremendous potential for tissue repair. However, the combined effects of nanofiber organization and immobilized bioactive factors on cell guidance are not well...
Nie Zuo-Ming, Zhang Zhi-Fang, Wang Dan, He Ping-An, Jiang Cai-Ying, Song Li, ...
Abstract Background The completion and reporting of baculovirus genomes is extremely important as it advances our understanding of gene function and evolution. Due to the large number of viral...
Molecular mechanism underlying chemosensitization of doxorubicin by selenium (2007)
Thesis (Ph.D.)--State University of New York at Buffalo, 2007.
FXR-Mediated Regulation of eNOS Expression in Vascular Endothelial Cells (2007)
Li, Jiang, Wilson, Annette, Kuruba, Ramalinga, Zhang, Qiuhong, Gao, Xiang, He, Fengtian, ...
Aims The farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily that is highly expressed in liver, kidney, adrenals, and intestine. FXR was previously proposed to play an...
FXR-mediated regulation of eNOS expression in vascular endothelial cells (2007)
Li, Jiang, Wilson, Annette, Kuruba, Ramalinga, Zhang, Qiuhong, Gao, Xiang, He, Fengtian, ...
Aims The farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily that is highly expressed in liver, kidney, adrenals, and intestine. FXR was previously proposed to play an...
Zhang, Qiuhong, He, Fengtian, Kuruba, Ramalinga, Gao, Xiang, Wilson, Annette, Li, Jiang, ...
Aims The farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily and plays an important role in the pathogenesis of cardiovascular diseases via regulating the metabolism and...
Zhang, Qiuhong, He, Fengtian, Kuruba, Ramalinga, Gao, Xiang, Wilson, Annette, Li, Jiang, ...
Aims The farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily and plays an important role in the pathogenesis of cardiovascular diseases via regulating the metabolism and...
Li, Song, Assmann, Sarah M., Albert, Reka
Plants both lose water and take in carbon dioxide through microscopic stomatal pores, each of which is regulated by a surrounding pair of guard cells. During drought, the plant hormone abscisic acid...
Song Li, Sarah M. Assmann, Réka Albert
Plants both lose water and take in carbon dioxide through microscopic stomatal pores, each of which is regulated by a surrounding pair of guard cells. During drought, the plant hormone abscisic acid...
Synthesis and Analgesic Activity Evaluation of Some Agmatine Derivatives (2006)
Hongxia He, Mengjia Liu, Zhibing Zheng, Ying Liu, Junhai Xiao, Ruibin Su, ...
A series of N,N’-disubstituted-2-nitroethene-1,1-diamine and N,N’-disubstituted- N’’-cyanoguanidine derivatives were prepared and evaluated for in...
Risch, Harvey A., McLaughlin, John R., Cole, David E. C., Rosen, Barry, Bradley, Linda, Fan, Isabel, ...
Background: BRCA1 and BRCA2 mutations in general populations and in various types of cancers have not been well characterized. We investigated the presence of these mutations in unselected patients...
Analysing Stochastic Call Demand With Time Varying Parameters (2005)
In spite of increasingly sophisticated workforce management tools, a significant gap remains between the goal of effective staffing and the present difficulty predicting the stochastic demand of...
Analysing Stochastic Call Demand With Time Varying Parameters (2005)
In spite of increasingly sophisticated workforce management tools, a significant gap remains between the goal of effective staffing and the present difficulty predicting the stochastic demand of...
Analysing Stochastic Call Demand With Time Varying Parameters (2005)
In spite of increasingly sophisticated workforce management tools, a significant gap remains between the goal of effective staffing and the present difficulty predicting the stochastic demand of...
Proteomic profiling of bone marrow mesenchymal stem cells upon TGF-beta stimulation (2004)
Wang, Daojing, Park, Jennifer S., Chu, Julia S.F., Ari, Krakowski, Luo, Kunxin, Chen, David J., ...
LUCY2: an interactive DNA sequence quality trimming and vector removal tool (2004)
Summary: LUCY2 is a raw DNA sequence trimming and visualization tool based on the popular command-line LUCY1. Users can change parameters, trim multiple sequences and visualize the results within an...
LUCY2: an interactive DNA sequence quality trimming and vector removal tool (2004)
Summary: Lucy2 is a raw DNA sequence trimming and visualization tool based on the popular command-line Lucy1. Users can change parameters, trim multiple sequences and visualize the results within an...
LUCY2: an interactive DNA sequence quality trimming and vector removal tool (2004)
Summary: LUCY2 is a raw DNA sequence trimming and visualization tool based on the popular command-line LUCY1. Users can change parameters, trim multiple sequences and visualize the results within an...
Neural network analysis of lymphoma microarray data: prognosis and diagnosis near-perfect (2003)
Abstract Background Microarray chips are being rapidly deployed as a major tool in genomic research. To date most of the analysis of the enormous amount of information provided on these chips has...
CFD (Computational Fluid Dynamics) is a widely used technique in engineering design field. It uses mathematical methods to simulate and predict flow characteristics in a certain physical space. Since...
Hirano, Seishiro, Cui , Xing, Li, Song, Kanno, Sanae, Kobayashi, Yayoi, Hayakawa, Toru, ...
Intake of inorganic arsenic is known to cause vascular diseases as well as skin lesions and cancer in humans. We investigated the differences in cytotoxicity, uptake rate of arsenic, and gene...
Shraim, Amjad, Cui, Xing, Li, Song, Ng, Jack C., Wang, Jianping Wang, Jin, Yinlong, ...
The extent of exposure of residents of Changqing (Guizhou, PR China) to arsenic through coal-burning was investigated. Despite the low coal-arsenic content (56.3±42.5 mg As kg−1) when compared...
Hou, Peng, Ji, Meiju, Ge, Cunwang, Shen, Jiayao, Li, Song, He, Nongyue, ...
Aberrant DNA methylation of the CpG site is among the earliest and most frequent alterations in cancer. Detection of promoter hypermethylation of cancer‐related genes may be useful for cancer...
Emission factors and emission inventories are subject to both variability and uncertainty. Variability refers to observed differences attributable to true heterogeneity or diversity in emissions....
Role of vicinal cysteine pairs in metalloid binding to the ArsD metalloregulatory protein (2001)
ArsD is a 120-residue repressor that regulates expression of the arsRDABC arsenical resistance operon of plasmid R773 in Escherichia coli . ArsD is released from ars promoter DNA by binding of the...
Role of vicinal cysteine pairs in metalloid binding to the arsd metalloregulatory protein / (2001)
Typescript.
Folic Acid Supplementation and Risk for Imperforate Anus in China (2001)
Myers, Melanie F., Li, Song, Correa-Villaseñor, Adolfo, Li, Zhu, Moore, Cynthia A., Hong, Shi Xin, ...
Maternal consumption of folic acid before pregnancy and during early pregnancy is associated with a reduced risk for some birth defects. Whether folic acid can reduce the risk for imperforate anus is...
Region-based Software Distributed Shared Memory (2000)
Song Li, Yu Lin, Michael Walker
In this paper, we describe the implementation of a software-based DSM model that supports variable-sized shard "regions", where a region is a logical page that can be adjusted according to...
Cerebral palsy and multiple births in China (2000)
Liu, Jian-meng, Li, Zhu, Lin, Qing, Zhao, Ping, Zhao, Feng-lin, Hong, Shi-xin, ...
Background A population-based study on prevalence of cerebral palsy in multiple births has not been carried out in China. The purpose of this paper was to determine the prevalence of cerebral palsy...
Modeling fracture and deformation of brittle rock under compressive loading (1999)
Axial tensile cracks in a uniaxial or low confining stress, triaxial compression test follow a compression-parallel straight path for long distances, often through the whole length of the test...
Modeling fracture and deformation of brittle rock under compressive loading (1999)
Axial tensile cracks in a uniaxial or low confining stress, triaxial compression test follow a compression-parallel straight path for long distances, often through the whole length of the test...
Modeling fracture and deformation of brittle rock under compressive loading (1999)
Axial tensile cracks in a uniaxial or low confining stress, triaxial compression test follow a compression-parallel straight path for long distances, often through the whole length of the test...
Modeling fracture and deformation of brittle rock under compressive loading (1999)
Axial tensile cracks in a uniaxial or low confining stress, triaxial compression test follow a compression-parallel straight path for long distances, often through the whole length of the test...
Modeling fracture and deformation of brittle rock under compressive loading (1999)
Axial tensile cracks in a uniaxial or low confining stress, triaxial compression test follow a compression-parallel straight path for long distances, often through the whole length of the test...
Modeling fracture and deformation of brittle rock under compressive loading (1999)
Axial tensile cracks in a uniaxial or low confining stress, triaxial compression test follow a compression-parallel straight path for long distances, often through the whole length of the test...
Targeted Delivery of Therapeutic Oligonucleotides for the Treatment of Prostate Cancer (1998)
Down-regulation of Bcl-2 expression via antisense oligodeoxynucleotides (ODN) may show promise as a novel therapy for the treatment of prostate cancer. The success of the antisense therapy is largely...
Targeted Delivery of Therapeutic Oligonucleotides for the Treatment of Prostate Cancer (1998)
Androgen independence and chemoresistance are the major obstacles in the treatment of patients with advanced prostate cancer (Denis & Murphy, 1993; Oh & Kantoff, 1998). Recent studies have suggested...
The Current Collection by High Voltage Solar Array from the Space Plasma, (1997)
Shifen, Gu, Liqin, Shi, Li, Song, Baoning, Tian
This article presents a type of theoretical statistical model which is capable of conveniently calculating high voltage solar array (HVSA) current collections given rise to by space plasma. Through...
Metis - An Object-Oriented Toolkit for Constructing Virtual Reality Applications (1997)
Russell Turner, Song Li, Enrico Gobbetti
: Virtual reality systems provide realistic look and feel by seamlessly integrating three-dimensional input and output devices. One software architecture approach to constructing such systems is to...
Multi-pulse laser holography of vibrating objects / (1996)
Thesis (M. Phil.)--University of Hong Kong, 1996.
Multi-pulse laser holography of vibrating objects / (1996)
Thesis (M. Phil.)--University of Hong Kong, 1996.
Multi-pulse laser holography of vibrating objects [electronic resource] / (1996)
Thesis (M.Phil.)--University of Hong Kong, 1996.
Multi-pulse laser holography of vibrating objects / (1996)
Thesis (M. Phil.)--University of Hong Kong, 1996.
On the term structure of interest rates--[microform] /--Song Li. (1992)
Department: Business.
Li, Song, Gao, Jimin, Satoh, Takashi, Friedman, Thea M., Edling, Andrea E., Koch, Ute, ...
The interaction between CD4 and major histocompatibility complex (MHC) class II proteins is critical for the activation of CD4+ T cells, which are involved in transplantation reactions and a number...
Nikitin, Alexander Yu., Juárez-Pérez, María I., Li, Song, Huang, Leaf, Lee, Wen-Hwa
Alterations in pathways mediated by retinoblastoma susceptibility gene (RB) product are among the most common in human cancer. Mice with a single copy of the Rb gene are shown to develop a syndrome...
Cappello, Michael, Li, Song, Chen, Xiaoai, Li, Chang-Ben, Harrison, Lisa, Narashimhan, Sukanya, ...
The tsetse thrombin inhibitor, a potent and specific low molecular mass (3,530 Da) anticoagulant peptide, was purified previously from salivary gland extracts of Glossina morsitans morsitans...
The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells
Li, Song, Butler, Peter, Wang, Yingxiao, Hu, Yingli, Han, Dong Cho, Usami, Shunichi, ...
The migration of vascular endothelial cells (ECs) is critical in vascular remodeling. We showed that fluid shear stress enhanced EC migration in flow direction and called this “mechanotaxis.” To...
Tzima, Eleni, Del Pozo, Miguel Angel, Kiosses, William B., Mohamed, Samih A., Li, Song, Chien, Shu, ...
Hemodynamic shear stress is a fundamental determinant of vascular remodeling and atherogenesis. Changes in focal adhesions, cytoskeletal organization and gene expression are major responses of...
Hou, Peng, Ji, Meiju, Ge, Cunwang, Shen, Jiayao, Li, Song, He, Nongyue, ...
Aberrant DNA methylation of the CpG site is among the earliest and most frequent alterations in cancer. Detection of promoter hypermethylation of cancer-related genes may be useful for cancer...
Zhang, Ming-Zhi, Mai, Weiyi, Li, Cunxi, Cho, Sae-youll, Hao, Chuanming, Moeckel, Gilbert, ...
Mutations of the polycystic kidney and hepatic disease 1 (PKHD1) gene have been shown to cause autosomal recessive polycystic kidney disease (ARPKD), but the cellular functions of the gene product...
Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress
Li, Song, Chen, Benjamin P.C., Azuma, Nobuyoshi, Hu, Ying-Li, Wu, Steven Z., Sumpio, Bauer E., ...
Shear stress, the tangential component of hemodynamic forces, plays an important role in endothelial remodeling. In this study, we investigated the role of Rho family GTPases Cdc42 and Rho in shear...
Inhibition of Pkhd1 Impairs Tubulomorphogenesis of Cultured IMCD CellsV⃞
Mai, Weiyi, Chen, Dong, Ding, Tianbing, Kim, Ingyu, Park, Sujun, Cho, Sae-youll, ...
Fibrocystin/polyductin (FPC), the gene product of PKHD1, is responsible for autosomal recessive polycystic kidney disease (ARPKD). This disease is characterized by symmetrically large kidneys with...
Design and Structure-Based Study of New Potential FKBP12 Inhibitors
Sun, Fei, Li, Pengyun, Ding, Yi, Wang, Liwei, Bartlam, Mark, Shu, Cuilin, ...
Based on the structure of FKBP12 complexed with FK506 or rapamycin, with computer-aided design, two neurotrophic ligands, (3R)-4-(p-Toluenesulfonyl)-1,4-thiazane-3-carboxylic acid-L-Leucine ethyl...
Rho Mediates the Shear-Enhancement of Endothelial Cell Migration and Traction Force Generation
Shiu, Yan-Ting, Li, Song, Marganski, William A., Usami, Shunichi, Schwartz, Martin A., Wang, Yu-Li, ...
The migration of vascular endothelial cells in vivo occurs in a fluid dynamic environment due to blood flow, but the role of hemodynamic forces in cell migration is not yet completely understood....
Tu, Zhijian, Li, Song, Mao, Chunhong
A novel family of tRNA-related SINEs named gecko was discovered in the yellow fever mosquito, Aedes aegypti. Approximately 7200 copies of gecko were distributed in the A. aegypti genome with a...
Li, Song, Assmann, Sarah M, Albert, Réka
Plants both lose water and take in carbon dioxide through microscopic stomatal pores, each of which is regulated by a surrounding pair of guard cells. During drought, the plant hormone abscisic acid...
Li, Song, Gao, Jimin, Satoh, Takashi, Friedman, Thea M., Edling, Andrea E., Koch, Ute, ...
The interaction between CD4 and major histocompatibility complex (MHC) class II proteins is critical for the activation of CD4+ T cells, which are involved in transplantation reactions and a number...
Nikitin, Alexander Yu., Juárez-Pérez, María I., Li, Song, Huang, Leaf, Lee, Wen-Hwa
Alterations in pathways mediated by retinoblastoma susceptibility gene (RB) product are among the most common in human cancer. Mice with a single copy of the Rb gene are shown to develop a syndrome...
Cappello, Michael, Li, Song, Chen, Xiaoai, Li, Chang-Ben, Harrison, Lisa, Narashimhan, Sukanya, ...
The tsetse thrombin inhibitor, a potent and specific low molecular mass (3,530 Da) anticoagulant peptide, was purified previously from salivary gland extracts of Glossina morsitans morsitans...
The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells
Li, Song, Butler, Peter, Wang, Yingxiao, Hu, Yingli, Han, Dong Cho, Usami, Shunichi, ...
The migration of vascular endothelial cells (ECs) is critical in vascular remodeling. We showed that fluid shear stress enhanced EC migration in flow direction and called this “mechanotaxis.” To...
Tzima, Eleni, Del Pozo, Miguel Angel, Kiosses, William B., Mohamed, Samih A., Li, Song, Chien, Shu, ...
Hemodynamic shear stress is a fundamental determinant of vascular remodeling and atherogenesis. Changes in focal adhesions, cytoskeletal organization and gene expression are major responses of...
Hou, Peng, Ji, Meiju, Ge, Cunwang, Shen, Jiayao, Li, Song, He, Nongyue, ...
Aberrant DNA methylation of the CpG site is among the earliest and most frequent alterations in cancer. Detection of promoter hypermethylation of cancer-related genes may be useful for cancer...
Zhang, Ming-Zhi, Mai, Weiyi, Li, Cunxi, Cho, Sae-youll, Hao, Chuanming, Moeckel, Gilbert, ...
Mutations of the polycystic kidney and hepatic disease 1 (PKHD1) gene have been shown to cause autosomal recessive polycystic kidney disease (ARPKD), but the cellular functions of the gene product...
Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress
Li, Song, Chen, Benjamin P.C., Azuma, Nobuyoshi, Hu, Ying-Li, Wu, Steven Z., Sumpio, Bauer E., ...
Shear stress, the tangential component of hemodynamic forces, plays an important role in endothelial remodeling. In this study, we investigated the role of Rho family GTPases Cdc42 and Rho in shear...
Inhibition of Pkhd1 Impairs Tubulomorphogenesis of Cultured IMCD CellsV⃞
Mai, Weiyi, Chen, Dong, Ding, Tianbing, Kim, Ingyu, Park, Sujun, Cho, Sae-youll, ...
Fibrocystin/polyductin (FPC), the gene product of PKHD1, is responsible for autosomal recessive polycystic kidney disease (ARPKD). This disease is characterized by symmetrically large kidneys with...
Design and Structure-Based Study of New Potential FKBP12 Inhibitors
Sun, Fei, Li, Pengyun, Ding, Yi, Wang, Liwei, Bartlam, Mark, Shu, Cuilin, ...
Based on the structure of FKBP12 complexed with FK506 or rapamycin, with computer-aided design, two neurotrophic ligands, (3R)-4-(p-Toluenesulfonyl)-1,4-thiazane-3-carboxylic acid-L-Leucine ethyl...
Rho Mediates the Shear-Enhancement of Endothelial Cell Migration and Traction Force Generation
Shiu, Yan-Ting, Li, Song, Marganski, William A., Usami, Shunichi, Schwartz, Martin A., Wang, Yu-Li, ...
The migration of vascular endothelial cells in vivo occurs in a fluid dynamic environment due to blood flow, but the role of hemodynamic forces in cell migration is not yet completely understood....
Tu, Zhijian, Li, Song, Mao, Chunhong
A novel family of tRNA-related SINEs named gecko was discovered in the yellow fever mosquito, Aedes aegypti. Approximately 7200 copies of gecko were distributed in the A. aegypti genome with a...
Li, Song, Assmann, Sarah M, Albert, Réka
Plants both lose water and take in carbon dioxide through microscopic stomatal pores, each of which is regulated by a surrounding pair of guard cells. During drought, the plant hormone abscisic acid...
Anisotropic mechanosensing by mesenchymal stem cells
Kurpinski, Kyle, Chu, Julia, Hashi, Craig, Li, Song
Mesenchymal stem cells (MSCs) are a potential source for the construction of tissue-engineered vascular grafts. However, how vascular mechanical forces regulate the genetic reprogramming in MSCs is...
Selective adapter recruitment and differential signaling networks by VEGF vs. shear stress
Wang, Yingxiao, Chang, Joann, Chen, Kuang-Den, Li, Song, Li, Julie Yi-Shuan, Wu, Chuanyue, ...
Vascular endothelial cells are continuously exposed to mechanical and chemical stimuli, such as shear stress and VEGF, respectively. It is still not clear how cells perceive these stimuli and...
Antithrombogenic property of bone marrow mesenchymal stem cells in nanofibrous vascular grafts
Hashi, Craig K., Zhu, Yiqian, Yang, Guo-Yuan, Young, William L., Hsiao, Benjamin S., Wang, Karin, ...
Nanostructured biomaterials have tremendous potential for tissue engineering. However, the performance and integration of the nanomaterials in vivo are not well understood. A challenge in vascular...
Mechanical Stimulation of Stem Cells Using Cyclic Uniaxial Strain
The role of mechanical forces in the development and maintenance of biological tissues is well documented, including several mechanically regulated phenomena such as bone remodeling, muscular...
Straub, Adam C., Clark, Katherine A., Ross, Mark A., Chandra, Ashwin G., Li, Song, Gao, Xiang, ...
Environmental arsenic exposure, through drinking contaminated water, is a significant risk factor for developing vascular diseases and is associated with liver portal hypertension, vascular shunting,...
Boolean network simulations for life scientists
Albert, István, Thakar, Juilee, Li, Song, Zhang, Ranran, Albert, Réka
Modern life sciences research increasingly relies on computational solutions, from large scale data analyses to theoretical modeling. Within the theoretical models Boolean networks occupy an...
The prevalence of BRCA1 mutations among young women with triple-negative breast cancer
Young, SR, Pilarski, Robert T, Donenberg, Talia, Shapiro, Charles, Hammond, Lyn S, Miller, Judith, ...
Androgen Deprivation by Activating the Liver X Receptor
Hoon Lee, Jung, Gong, Haibiao, Khadem, Shaheen, Lu, Yi, Gao, Xiang, Li, Song, ...
Prostate cancer is the most commonly diagnosed and the second leading cause of cancer death in men. The androgens-androgen receptor signaling plays an important role in normal prostate development,...