Stover, Elizabeth H, Boulton, Christina L, Gotlib, Jason, Legare, Robert D, Amaral, Sonia M, ...
FIP1L1-PDGFRalpha causes hypereosinophilic syndrome (HES) and is inhibited by the tyrosine kinase inhibitor imatinib (Gleevec). Imatinib is a potent inhibitor of ABL, ARG, PDGFRalpha, PDGFRbeta, and...
PML/RARα and FLT3-ITD induce an APL-like disease in a mouse model
Kelly, Louise M., Kutok, Jeffrey L., Williams, Ifor R., Boulton, Christina L., Amaral, Sonia M., Curley, David P., ...
Acute promyelocytic leukemia (APL) cells invariably express aberrant fusion proteins involving the retinoic acid receptor α (RARα). The most common fusion partner is promyelocytic leukemia protein...
PML/RARα and FLT3-ITD induce an APL-like disease in a mouse model
Kelly, Louise M., Kutok, Jeffrey L., Williams, Ifor R., Boulton, Christina L., Amaral, Sonia M., Curley, David P., ...
Acute promyelocytic leukemia (APL) cells invariably express aberrant fusion proteins involving the retinoic acid receptor α (RARα). The most common fusion partner is promyelocytic leukemia protein...