Sophie Goyard

A set of independent selectable markers for transfection of the human malaria parasite Plasmodium falciparum

Mamoun, Choukri Ben, Gluzman, Ilya Y., Goyard, Sophie, Beverley, Stephen M., Goldberg, Daniel E.

Genomic information is rapidly accumulating for the human malaria pathogen, Plasmodium falciparum. Our ability to perform genetic manipulations to understand Plasmodium gene function is limited....

A set of independent selectable markers for transfection of the human malaria parasite Plasmodium falciparum

Mamoun, Choukri Ben, Gluzman, Ilya Y., Goyard, Sophie, Beverley, Stephen M., Goldberg, Daniel E.

Genomic information is rapidly accumulating for the human malaria pathogen, Plasmodium falciparum. Our ability to perform genetic manipulations to understand Plasmodium gene function is limited....

Protein O-Mannosyltransferase Isoforms Regulate Biofilm Formation in Candida albicans

Peltroche-Llacsahuanga, Heidrun, Goyard, Sophie, D′Enfert, Christophe, Prill, Stephan K.-H., Ernst, Joachim F.

Five isoforms of protein mannosyltransferase (Pmt) O-mannosylate secretory proteins in Candida albicans. pmt mutants were differentially defective for biofilm formation on plastic in static and...

Putting the Leishmania genome to work: functional genomics by transposon trapping and expression profiling.

Beverley, Stephen M, Akopyants, Natalia S, Goyard, Sophie, Matlib, Robin S, Gordon, Jennifer L, Brownstein, Bernard H, ...

Leishmania are important protozoan pathogens of humans in temperate and tropical regions. The study of gene expression during the infectious cycle, in mutants or after environmental or chemical...

Optimization of Topical Therapy for Leishmania major Localized Cutaneous Leishmaniasis Using a Reliable C57BL/6 Model

Lecoeur, Hervé, Buffet, Pierre, Morizot, Gloria, Goyard, Sophie, Guigon, Ghislaine, Milon, Geneviève, ...

When initiating the cutaneous disease named cutaneous leishmaniasis (CL), Leishmania parasites develop within the parasitophorous vacuoles of phagocytes residing in and/or recruited to the dermis, a...

The Yak1 Kinase Is Involved in the Initiation and Maintenance of Hyphal Growth in Candida albicans

Goyard, Sophie, Knechtle, Philipp, Chauvel, Murielle, Mallet, Adeline, Prévost, Marie-Christine, Proux, Caroline, ...

Members of the dual-specificity tyrosine-phosphorylated and regulated kinase (DYRK) family perform a variety of functions in eukaryotes. We used gene disruption, targeted pharmacologic inhibition,...