Lorentz JÄNTSCHI, Sorana BOLBOACĂ
Octanol-water partition coefficient of two hundred and six polychlorinated biphenyls was model by the use of an original method based on complex information obtained from compounds structure. The...
Sorana BOLBOACĂ, Lorentz JÄNTSCHI
The neonicotinoids are the newest major class of insecticides modeled after the basic nicotine molecule having improved insecticide activity and generally low toxicity. The insecticidal activities of...
In trial, when the results are reported as dichotomies variables, the most important measure of effect are represented by the relative risk reduction, absolute risk reduction and number needed to...
Lorentz JÄNTSCHI, Sorana BOLBOACĂ
The molecular descriptors family on structure activity relationships methodology was applied on ten cyclic organophosphorus compounds in order to predict theirs molar refraction. A number of 107692...
Sorana BOLBOACĂ, Lorentz JÄNTSCHI
The antituberculotic activity of some polyhydroxyxanthones was estimated using the Molecular Descriptors Family on Structure Activity Relationships methodology. From a total number of 298110 real and...
Binomial Distribution Sample Confidence Intervals Estimation 6. Excess Risk (2004)
Sorana BOLBOACĂ, Andrei ACHIMAŞ CADARIU
We present the problem of the confidence interval estimation for excess risk (Y/n-X/m fraction), a parameter which allows evaluating of the specificity of an association between predisposing or...
Binomial Distribution Sample Confidence Intervals Estimation 5. Odds Ratio (2004)
Sorana BOLBOACĂ, Andrei ACHIMAŞ CADARIU
Evaluation of the strength of association between predisposing or causal factors and disease can be express as odds ratio in case-control studies. In order to interpret correctly a point estimation...
Relational Information in Pharmacology: A Challenge (2004)
A large amount of pharmaceutical information exists and new knowledge’s are created every day. Organizing pharmaceutical information is an important task because a correct organization of...
Sorana BOLBOACĂ, Andrei ACHIMAŞ CADARIU
Assessments of a controlled clinical trial suppose to interpret some key parameters as the controlled event rate, experimental event date, relative risk, absolute risk reduction, relative risk...
Binomial Distribution Sample Confidence Intervals Estimation 8. Number Needed to Treat/Harm (2004)
Sorana BOLBOACĂ, Andrei ACHIMAŞ CADARIU
Nowadays, the number needed to treat became the most important parameter in reporting the treatment effects in clinical trials, from binary outcomes such as “positive” or “negative”. Defined...
Tudor DRUGAN, Sorana BOLBOACĂ, Lorentz JÄNTSCHI, Andrei ACHIMAŞ CADARIU
The aim of the paper was to present the usefulness of the binomial distribution in studying of the contingency tables and the problems of approximation to normality of binomial distribution (the...
Sorana BOLBOACĂ, Andrei ACHIMAŞ CADARIU
The accuracy of confidence interval expressing is one of most important problems in medical statistics. In the paper was considers for accuracy analysis from literature, a number of confidence...
Binomial Distribution Sample Confidence Intervals Estimation 3. Post and Pre Test Odds (2003)
Sorana BOLBOACĂ, Andrei ACHIMAŞ CADARIU
When a diagnostic test results are dichotomous a 2´2 contingency table can be create, and some indices can be compute according to the method in which the data were collected. The posttest odds is...
Binomial Distribution Sample Confidence Intervals Estimation 4. Post Test Probability (2003)
Sorana BOLBOACĂ, Andrei ACHIMAŞ CADARIU
Posttest probability is one of the key parameters which can be measured and interpret in dichotomous diagnostic tests. Defined as the proportion of patients, which present particular test result and...
BOLBOACĂ, Sorana, JÄNTSCHI, Lorentz
Likelihood Ratio medical key parameters calculated on categorical results from diagnostic tests are usually express accompanied with their confidence intervals, computed using the normal distribution...