A reassessment of the Carnot cycle and the concept of entropy (2008)
It is argued that the Carnot cycle is a highly inaccurate representation of a steam engine, and that the net work obtained in its operation would be zero. This conclusion is also supported by an...
On the status of the Michaelis-Menten equation and its implications for enzymology (2008)
The Michaelis-Menten equation (MME) is considered to be the fundamental equation describing the rates of enzyme-catalysed reactions, and thus the 'physicochemical key' to understanding all...
Quantum theory: undulating foundations, uncertain principles? (2008)
Intriguing questions from the early history of quantum theory (QT) raise serious doubts about the accepted theory of blackbody radiation. (The Planck theory builds on the apparently flawed...
Previous proposals for the origin of molecular homochirality, based on the effect of the weak neutral current (WNC) on enantiomers, and the amplification of the resultant parity-violating energy...
Gravity as centripetal force (2007)
The earth’s gravity can be viewed as the centripetal force resulting from the coupling of its rotational and orbital motions. These motions were (presumably) set in train in the early universe,...
Reformulation of activated complex theory (2007)
The key assumption of activated complex theory (ACT), that the AC is in thermodynamic equilibrium with the reactants, needs to be reconsidered. This is because the formation of the AC is slower than...
Chandrasekhar, Sosale, Karri, Phaneendrasai
2-Phenyl-5(4H)-oxazolone (azlactone) reacts with aliphatic aldehydes upon adsorption on neutral alumina and irradiation with microwaves (
Chandrasekhar, Sosale, Karri, Phaneendrasai
2-Phenyl-5(4H)-oxazolone (azlactone) reacts with aliphatic aldehydes upon adsorption on neutral alumina and irradiation with microwaves (
Previous proposals for the origin of molecular homochirality, based on the effect of the weak neutral current (WNC) on enantiomers, and the amplification of the resultant parity-violating energy...
Chandrasekhar, Sosale, Gorla, Suresh Kumar
Three tricyclic imides were prepared by a Diels–Alder reaction of 6-arylfulvenes and maleic anhydride, followed by treatment with $NH_3$. The exo isomers were found to exist as conglomerates when...
Chandrasekhar, Sosale, Gorla, Suresh Kumar
Three tricyclic imides were prepared by a Diels–Alder reaction of 6-arylfulvenes and maleic anhydride, followed by treatment with $NH_3$. The exo isomers were found to exist as conglomerates when...
Chandrasekhar, Sosale, Hota, Raghunandan
Ketones can be reduced with $NaBH_4$ in diglyme without an apparent proton source, but putatively catalyzed by a trialkyl borate. This can be initially derived in situ from $NaBH_4$ and an alc.,...
Chandrasekhar, Sosale, Hota, Raghunandan
Ketones can be reduced with $NaBH_4$ in diglyme without an apparent proton source, but putatively catalyzed by a trialkyl borate. This can be initially derived in situ from $NaBH_4$ and an alc.,...
Chandrasekhar, Sosale, Kulkarni, Guruprasad, Muktha, B, Guru Row, Tayur N
The first complex of triphenylphosphine oxide $(Ph_3PO)$ with a chiral substrate, formed by crystallising Ph3PO in the presence of the synthetically important chiral auxiliary...
Chandrasekhar, Sosale, Kulkarni, Guruprasad, Muktha, B, Guru Row, Tayur N
The first complex of triphenylphosphine oxide $(Ph_3PO)$ with a chiral substrate, formed by crystallising Ph3PO in the presence of the synthetically important chiral auxiliary...
Chandrasekhar, Sosale, Gopalaiah, Kovuru
Ketoximes and aromatic aldoximes are converted to the corresponding carbonyl compounds in excellent yields (67–97%), upon treatment with a suspension of iodic acid in dry $CH_2Cl_2$ at room...
Chandrasekhar, Sosale, Gopalaiah, Kovuru
Ketoximes and aromatic aldoximes are converted to the corresponding carbonyl compounds in excellent yields (67–97%), upon treatment with a suspension of iodic acid in dry $CH_2Cl_2$ at room...
Novel fulvenes capto-dativelly substituted at $C_6$ (2001)
Chandrasekhar, Sosale, Sridharan, Rajagopal
A set of four fulvenes bearing both electron-withdrawing and -donating aryl groups at $C_6$ was prepared and shown to be fairly stable, except for the dimerisation of the anisyl-nitrophenyl-fulvene...
Beckmann rearrangement in the solid state: reaction of oxime hydrochlorides (2001)
Chandrasekhar, Sosale, Gopalaiah, Kovuru
Several ketoxime hydrochlorides undergo Beckmann rearrangement upon heating below their melting points for 5-48 h, in excellent yields (generally >70%). The absence of a reaction solvent and of...
Novel fulvenes capto-dativelly substituted at $C_6$ (2001)
Chandrasekhar, Sosale, Sridharan, Rajagopal
A set of four fulvenes bearing both electron-withdrawing and -donating aryl groups at $C_6$ was prepared and shown to be fairly stable, except for the dimerisation of the anisyl-nitrophenyl-fulvene...
Anilkumar, R, Chandrasekhar, Sosale, Malayalam, Sridhar
The titled triazine can be alkylated with LDA and a variety of alkyl halides: subsequent reduction with aluminium amalgam cleaves the naphthotriazine moiety to afford substituted $\alpha$ amino acids...
Anilkumar, R, Chandrasekhar, Sosale, Malayalam, Sridhar
The titled triazine can be alkylated with LDA and a variety of alkyl halides: subsequent reduction with aluminium amalgam cleaves the naphthotriazine moiety to afford substituted $\alpha$ amino acids...
'Preferential spontaneous resolution' of p-anisyl \alpha-methylbenzyl ketone (1989)
Chandrasekhar, Sosale, Ravindranath, Mukkamala
The title compound has been obtained in optically-active form without using any chiral influence, by 'preferential spontaneous resolution'. 'Preferential Spontaneous Resolution' results in the...
'Preferential spontaneous resolution' of p-anisyl \alpha-methylbenzyl ketone (1989)
Chandrasekhar, Sosale, Ravindranath, Mukkamala
The title compound has been obtained in optically-active form without using any chiral influence, by 'preferential spontaneous resolution'. 'Preferential Spontaneous Resolution' results in the...
Chandrasekhar, Sosale, Roy, Chandra Deo
An intramolecular Baeyer-Villiger reaction has been effected involving a conformationally-fixed intermediate which breaks down with stereoelectronic control.
Chandrasekhar, Sosale, Murthy, Tara
Hydride reduction of dibromoketones $RCOCHBr_2$ $(R=Ph, CMe_3)$ gave $RCH(OH)CHBr_2$, which, when treated with KOH in $CCl_4$, gave aldehydes RCHBrCHO via intermediate bromoepoxides I. Grignard...
Product Stability in Kinetically-Controlled Organic Reactions (1987)
Few organic reactions yield a single product. Therefore, an appreciation of the factors which affect the distribution of products in organic reactions is of great importance. While external variables...
Chandrasekhar, Sosale, Roy, Chandra Deo
An intramolecular Baeyer-Villiger reaction has been effected involving a conformationally-fixed intermediate which breaks down with stereoelectronic control.
Chandrasekhar, Sosale, Murthy, Tara
Hydride reduction of dibromoketones $RCOCHBr_2$ $(R=Ph, CMe_3)$ gave $RCH(OH)CHBr_2$, which, when treated with KOH in $CCl_4$, gave aldehydes RCHBrCHO via intermediate bromoepoxides I. Grignard...
Product Stability in Kinetically-Controlled Organic Reactions (1987)
Few organic reactions yield a single product. Therefore, an appreciation of the factors which affect the distribution of products in organic reactions is of great importance. While external variables...