Stefan A. Muljo

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing (2005)

Kanellopoulou, Chryssa, Muljo, Stefan A., Kung, Andrew L., Ganesan, Shridar, Drapkin, Ronny, Jenuwein, Thomas, ...

Dicer is the enzyme that cleaves double-stranded RNA (dsRNA) into 21–25-nt-long species responsible for sequence-specific RNA-induced gene silencing at the transcriptional, post-transcriptional, or...

The variable, CH1, CH2 and CH3 domains of Ig heavy chain are dispensable for pre-BCR function in transgenic mice (2002)

Muljo, Stefan A., Schlissel, Mark S.

The pre‐BCR consists of Ig µ protein, the product of a heavy chain gene assembled by V(D)J recombination in pro‐B cells, the surrogate light chains Vpre‐B and λ5, and the signaling...

Pro-B-Cell-Specific Transcription and Proapoptotic Function of Protein Kinase Cη

Morrow, Theresa A., Muljo, Stefan A., Zhang, Jun, Hardwick, J. Marie, Schlissel, Mark S.

Using a subtractive cloning scheme on cDNA prepared from primary pro-B and pre-B cells, we identified several genes whose products regulate apoptosis. We further characterized one of these genes,...

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

Kanellopoulou, Chryssa, Muljo, Stefan A., Kung, Andrew L., Ganesan, Shridar, Drapkin, Ronny, Jenuwein, Thomas, ...

Dicer is the enzyme that cleaves double-stranded RNA (dsRNA) into 21–25-nt-long species responsible for sequence-specific RNA-induced gene silencing at the transcriptional, post-transcriptional, or...

Pro-B-Cell-Specific Transcription and Proapoptotic Function of Protein Kinase Cη

Morrow, Theresa A., Muljo, Stefan A., Zhang, Jun, Hardwick, J. Marie, Schlissel, Mark S.

Using a subtractive cloning scheme on cDNA prepared from primary pro-B and pre-B cells, we identified several genes whose products regulate apoptosis. We further characterized one of these genes,...

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

Kanellopoulou, Chryssa, Muljo, Stefan A., Kung, Andrew L., Ganesan, Shridar, Drapkin, Ronny, Jenuwein, Thomas, ...

Dicer is the enzyme that cleaves double-stranded RNA (dsRNA) into 21–25-nt-long species responsible for sequence-specific RNA-induced gene silencing at the transcriptional, post-transcriptional, or...

Aberrant T cell differentiation in the absence of Dicer

Muljo, Stefan A., Ansel, K. Mark, Kanellopoulou, Chryssa, Livingston, David M., Rao, Anjana, Rajewsky, Klaus

Dicer is an RNaseIII-like enzyme that is required for generating short interfering RNAs and microRNAs. The latter have been implicated in regulating cell fate determination in invertebrates and...

X chromosome inactivation in the absence of Dicer

Kanellopoulou, Chryssa, Muljo, Stefan A., Dimitrov, Stoil D., Chen, Xi, Colin, Christian, Plath, Kathrin, ...

Dicer is central to the RNA interference (RNAi) pathway, because it is required for processing of double-stranded RNA (dsRNA) precursors into small RNA effector molecules. In principle, any long...