SMP BIOINFORMATICS BIOINFORMATICS – WHAT THE DATA REALLY MEAN (2009)
Elena Reiffel, Stefanie Scheid, Florian Markowetz, Stefan Bentink
Clinic, 26 young scientists are sitting engrossed in their work at computer terminals. In four days the participants are to learn as much as possible about the statistical analysis of DNA microarray...
Pleiotropic hierarchies from high-dimensional phenotyping by (2008)
Florian Markowetz, Juby Jacob, Stefan Bentink, Rainer Spang
RNA interference
Jacob, Juby, Jentsch, Marcel, Kostka, Dennis, Bentink, Stefan, Spang, Rainer
Motivation: Molecular diagnostics aims at classifying diseases into clinically relevant sub-entities based on molecular characteristics. Typically, the entities are split into subgroups, which might...
Jacob, Juby, Jentsch, Marcel, Kostka, Dennis, Bentink, Stefan, Spang, Rainer
Motivation: Molecular diagnostics aims at classifying diseases into clinically relevant sub-entities based on molecular characteristics. Typically, the entities are split into subgroups, which might...
Computational Diagnostics Group (2007)
Claudio Lottaz, Stefan Bentink, Rainer Spang
From a machine learning point of view, classification of gene expression patterns is a very particular task. Typically, training data consists of few samples (small number of experiments) but...
A Biologic Definition of Burkitt's Lymphoma from Transcriptional and Genomic Profiling (2006)
Hummel, Michael, Bentink, Stefan, Berger, Hilmar, Klapper, Wolfram, Wessendorf, Swen, Barth, Thomas F.E., ...
Background: The distinction between Burkitt's lymphoma and diffuse large-B-cell lymphoma is unclear. We used transcriptional and genomic profiling to define Burkitt's lymphoma more precisely and to...
am Fachbereich Mathematik und Informatik (2006)
Florian Markowetz, Viola Gesellchen, Britta Koch, Stefanie Scheid, Stefan Bentink, Stefan Haas
Acknowledgements This work was carried out in the Computational Diagnostics
Detecting common gene expression patterns in multiple cancer outcome entities (2005)
Yang, Xinan, Bentink, Stefan, Spang, Rainer
Most oncological microarray studies focus on molecular distinctions in different cancer entities. Recently, researchers started using microarrays for investigating molecular commonalities of multiple...
Gene Ontology as a tool for the systematic analysis of large-scale gene-expression data (2003)
Stefan Bentink, Im Aufbaustudiengang Bioinformatik
Approach: Technologies like micro- or macroarrays are the source of various problems concerning analysis and evaluation of the datasets obtained. In the present thesis a functional classification...
Gene Ontology Driven Classification (2003)
Of Gene Expression, Claudio Lottaz, Stefan Bentink, Renate Kirschner, Christian Hagemeier, Rainer Spang
Introduction From a machine learning point of view, classification of gene expression patterns is a very particular task. Typically, training data consists of few samples (small number of...
Bader, Teresa, Schröppel, Klaus, Bentink, Stefan, Agabian, Nina, Köhler, Gerwald, Morschhäuser, Joachim
By generating a calcineurin mutant of the Candida albicans wild-type strain SC5314 with the help of a new recyclable dominant selection marker, we confirmed that calcineurin mediates tolerance to a...
Bader, Teresa, Schröppel, Klaus, Bentink, Stefan, Agabian, Nina, Köhler, Gerwald, Morschhäuser, Joachim
By generating a calcineurin mutant of the Candida albicans wild-type strain SC5314 with the help of a new recyclable dominant selection marker, we confirmed that calcineurin mediates tolerance to a...
Hirsch, Burkhard, Hummel, Michael, Bentink, Stefan, Fouladi, Fariba, Spang, Rainer, Zollinger, Raphael, ...
High CD30 expression in classical Hodgkin’s lymphoma and anaplastic large cell lymphoma (ALCL) suggests an important pathogenic role of this cytokine receptor. To test this hypothesis, we...