Allen, Thomas E., Heidmann, Stefan, Reed, RoseMary, Myler, Peter J., Göringer, H. Ulrich, Stuart, Kenneth D.
RNA editing in Trypanosoma brucei mitochondria produces mature mRNAs by a series of enzyme-catalyzed reactions that specifically insert or delete uridylates in association with a macromolecular...
Proteolytic cleavage of the THR subunit during anaphase limits Drosophila separase function
Herzig, Alf, Lehner, Christian F., Heidmann, Stefan
Sister-chromatid separation in mitosis requires proteolytic cleavage of a cohesin subunit. Separase, the corresponding protease, is activated at the metaphase-to-anaphase transition. Activation...
Degradation of Drosophila PIM regulates sister chromatid separation during mitosis
Leismann, Oliver, Herzig, Alf, Heidmann, Stefan, Lehner, Christian F.
Drosophila Pimples (PIM) and Three rows (THR) are required for sister chromatid separation in mitosis. PIM accumulates during interphase and is degraded rapidly during mitosis. This degradation is...
Genetic interactions of separase regulatory subunits reveal the diverged Drosophila Cenp-C homolog
Heeger, Sebastian, Leismann, Oliver, Schittenhelm, Ralf, Schraidt, Oliver, Heidmann, Stefan, Lehner, Christian F.
Faithful transmission of genetic information during mitotic divisions depends on bipolar attachment of sister kinetochores to the mitotic spindle and on complete resolution of sister-chromatid...
A hammerhead ribozyme substrate and reporter for in vitro kinetoplastid RNA editing.
Wang, Bingbing, Salavati, Reza, Heidmann, Stefan, Stuart, Kenneth
Current in vitro assays for RNA editing in kinetoplastids directly examine the products generated by incubation of pre-mRNA substrate with guide RNA (gRNA) and mitochondrial (mt) extract. RNA editing...
Drosophila Separase is required for sister chromatid separation and binds to PIM and THR
Jäger, Hubert, Herzig, Alf, Lehner, Christian F., Heidmann, Stefan
Drosophila PIM and THR are required for sister chromatid separation in mitosis and associate in vivo. Neither of these two proteins shares significant sequence similarity with known proteins....
Allen, Thomas E., Heidmann, Stefan, Reed, RoseMary, Myler, Peter J., Göringer, H. Ulrich, Stuart, Kenneth D.
RNA editing in Trypanosoma brucei mitochondria produces mature mRNAs by a series of enzyme-catalyzed reactions that specifically insert or delete uridylates in association with a macromolecular...
Proteolytic cleavage of the THR subunit during anaphase limits Drosophila separase function
Herzig, Alf, Lehner, Christian F., Heidmann, Stefan
Sister-chromatid separation in mitosis requires proteolytic cleavage of a cohesin subunit. Separase, the corresponding protease, is activated at the metaphase-to-anaphase transition. Activation...
Drosophila Separase is required for sister chromatid separation and binds to PIM and THR
Jäger, Hubert, Herzig, Alf, Lehner, Christian F., Heidmann, Stefan
Drosophila PIM and THR are required for sister chromatid separation in mitosis and associate in vivo. Neither of these two proteins shares significant sequence similarity with known proteins....
Degradation of Drosophila PIM regulates sister chromatid separation during mitosis
Leismann, Oliver, Herzig, Alf, Heidmann, Stefan, Lehner, Christian F.
Drosophila Pimples (PIM) and Three rows (THR) are required for sister chromatid separation in mitosis. PIM accumulates during interphase and is degraded rapidly during mitosis. This degradation is...
Genetic interactions of separase regulatory subunits reveal the diverged Drosophila Cenp-C homolog
Heeger, Sebastian, Leismann, Oliver, Schittenhelm, Ralf, Schraidt, Oliver, Heidmann, Stefan, Lehner, Christian F.
Faithful transmission of genetic information during mitotic divisions depends on bipolar attachment of sister kinetochores to the mitotic spindle and on complete resolution of sister-chromatid...
A hammerhead ribozyme substrate and reporter for in vitro kinetoplastid RNA editing.
Wang, Bingbing, Salavati, Reza, Heidmann, Stefan, Stuart, Kenneth
Current in vitro assays for RNA editing in kinetoplastids directly examine the products generated by incubation of pre-mRNA substrate with guide RNA (gRNA) and mitochondrial (mt) extract. RNA editing...
Schittenhelm, Ralf B., Heeger, Sebastian, Althoff, Friederike, Walter, Anne, Heidmann, Stefan, Mechtler, Karl, ...
Chromosome segregation during meiosis and mitosis depends on the assembly of functional kinetochores within centromeric regions. Centromeric DNA and kinetochore proteins show surprisingly little...
Cell-Type-Specific TEV Protease Cleavage Reveals Cohesin Functions in Drosophila Neurons
Pauli, Andrea, Althoff, Friederike, Oliveira, Raquel A., Heidmann, Stefan, Schuldiner, Oren, Lehner, Christian F., ...
Cohesin is a highly conserved multisubunit complex that holds sister chromatids together in mitotic cells. At the metaphase to anaphase transition, proteolytic cleavage of the α kleisin subunit...