Stefanie Kaech

Volatile anesthetics block actin-based motility in dendritic spines

Kaech, Stefanie, Brinkhaus, Heike, Matus, Andrew

Dendritic spines form the postsynaptic contact sites for most excitatory synapses in the brain. Spines occur in a wide range of different shapes that can vary depending on an animal’s experience or...

Cytoskeletal microdifferentiation: A mechanism for organizing morphological plasticity in dendrites

Kaech, Stefanie, Parmar, Hema, Roelandse, Martijn, Bornmann, Caroline, Matus, Andrew

Experimental evidence suggests that microfilaments and microtubules play contrasting roles in regulating the balance between motility and stability in neuronal structures. Actin-containing...

Volatile anesthetics block actin-based motility in dendritic spines

Kaech, Stefanie, Brinkhaus, Heike, Matus, Andrew

Dendritic spines form the postsynaptic contact sites for most excitatory synapses in the brain. Spines occur in a wide range of different shapes that can vary depending on an animal’s experience or...

Cytoskeletal microdifferentiation: A mechanism for organizing morphological plasticity in dendrites

Kaech, Stefanie, Parmar, Hema, Roelandse, Martijn, Bornmann, Caroline, Matus, Andrew

Experimental evidence suggests that microfilaments and microtubules play contrasting roles in regulating the balance between motility and stability in neuronal structures. Actin-containing...

Direct Observations of the Mechanical Behaviors of the Cytoskeleton in Living Fibroblasts

Heidemann, Steven R., Kaech, Stefanie, Buxbaum, Robert E., Matus, Andrew

Cytoskeletal proteins tagged with green fluorescent protein were used to directly visualize the mechanical role of the cytoskeleton in determining cell shape. Rat embryo (REF 52) fibroblasts were...