Stefano Casola

Attenuated liver fibrosis in the absence of B cells

Novobrantseva, Tatiana I., Majeau, Gerard R., Amatucci, Aldo, Kogan, Sophia, Brenner, Ian, Casola, Stefano, ...

Analysis of mononuclear cells in the adult mouse liver revealed that B cells represent as much as half of the intrahepatic lymphocyte population. Intrahepatic B cells (IHB cells) are phenotypically...

Relaxation of Insulin-like Growth Factor 2 Imprinting and Discordant Methylation at KvDMR1 in Two First Cousins Affected by Beckwith-Wiedemann and Klippel-Trenaunay-Weber Syndromes

Sperandeo, Maria Pia, Ungaro, Paola, Vernucci, Maria, Pedone, Paolo V., Cerrato, Flavia, Perone, Lucia, ...

Beckwith-Wiedeman syndrome (BWS) and Klippel-Trenaunay-Weber syndrome (KTWS) are different human disorders characterized, among other features, by tissue overgrowth. Deregulation of one or more...

Tracking germinal center B cells expressing germ-line immunoglobulin γ1 transcripts by conditional gene targeting

Casola, Stefano, Cattoretti, Giorgio, Uyttersprot, Nathalie, Koralov, Sergei B., Segal, Jane, Hao, Zhenyue, ...

Germinal centers (GCs) represent the main sites for the generation of high-affinity, class-switched antibodies during T cell-dependent antibody responses. To study gene function specifically in GC B...

Attenuated liver fibrosis in the absence of B cells

Novobrantseva, Tatiana I., Majeau, Gerard R., Amatucci, Aldo, Kogan, Sophia, Brenner, Ian, Casola, Stefano, ...

Analysis of mononuclear cells in the adult mouse liver revealed that B cells represent as much as half of the intrahepatic lymphocyte population. Intrahepatic B cells (IHB cells) are phenotypically...

Relaxation of Insulin-like Growth Factor 2 Imprinting and Discordant Methylation at KvDMR1 in Two First Cousins Affected by Beckwith-Wiedemann and Klippel-Trenaunay-Weber Syndromes

Sperandeo, Maria Pia, Ungaro, Paola, Vernucci, Maria, Pedone, Paolo V., Cerrato, Flavia, Perone, Lucia, ...

Beckwith-Wiedeman syndrome (BWS) and Klippel-Trenaunay-Weber syndrome (KTWS) are different human disorders characterized, among other features, by tissue overgrowth. Deregulation of one or more...

Tracking germinal center B cells expressing germ-line immunoglobulin γ1 transcripts by conditional gene targeting

Casola, Stefano, Cattoretti, Giorgio, Uyttersprot, Nathalie, Koralov, Sergei B., Seagal, Jane, Hao, Zhenyue, ...

Germinal centers (GCs) represent the main sites for the generation of high-affinity, class-switched antibodies during T cell-dependent antibody responses. To study gene function specifically in GC B...

PLC-γ2 is essential for formation and maintenance of memory B cells

Hikida, Masaki, Casola, Stefano, Takahashi, Noriko, Kaji, Tomohiro, Takemori, Toshitada, Rajewsky, Klaus, ...

Resting antigen-experienced memory B cells are thought to be responsible for the more rapid and robust antibody responses after antigen reencounter, which are the hallmark of memory humoral...

Jmjd3 contributes to the control of gene expression in LPS-activated macrophages

De Santa, Francesca, Narang, Vipin, Yap, Zhei Hwee, Tusi, Betsabeh Khoramian, Burgold, Thomas, Austenaa, Liv, ...

Jmjd3, a JmjC family histone demethylase, is induced by the transcription factor NF-kB in response to microbial stimuli. Jmjd3 erases H3K27me3, a histone mark associated with transcriptional...