A novel similarity-measure for the analysis of genetic data in complex phenotypes (2009)
Lagani, Vincenzo, Montesanto, Alberto, Di Cianni, Fausta, Moreno, Victor, Landi, Stefano, Conforti, Domenico, ...
Abstract Background Recent technological advances in DNA sequencing and genotyping have led to the accumulation of a remarkable quantity of data on genetic polymorphisms. However, the development of...
Garritano, Sonia, Gemignani, Federica, Voegele, Catherine, Nguyen-Dumont, Tú, Le Calvez-Kelm, Florence, De Silva, Deepika, ...
Abstract Background Together single nucleotide substitutions and small insertion/deletion variants are the most common form of sequence variation in the human gene pool. High-resolution SNP profile...
HAS-1 genetic polymorphism in sporadic abdominal aortic aneurysm (2009)
Chiara Armani, Stefano Landi, Marco Nuti, Rossella Di Stefano, Alberto Balbarini
The hyaluronan synthase 1 (HAS-1) gene encodes a plasma membrane protein that synthesizes hyaluronan (HA), an extracellular matrix molecule. Accumulating evidence emphasizes the relevance of HA...
HAS-1 genetic polymorphism in sporadic abdominal aortic aneurysm (2009)
Chiara Armani, Stefano Landi, Marco Nuti, Rossella Di Stefano, Alberto Balbarini
The hyaluronan synthase 1 (HAS-1) gene encodes a plasma membrane protein that synthesizes hyaluronan (HA), an extracellular matrix molecule. Accumulating evidence emphasizes the relevance of HA...
HAS-1 genetic polymorphism in sporadic abdominal aortic aneurysm (2009)
Chiara Armani, Stefano Landi, Marco Nuti, Rossella Di Stefano, Alberto Balbarini
The hyaluronan synthase 1 (HAS-1) gene encodes a plasma membrane protein that synthesizes hyaluronan (HA), an extracellular matrix molecule. Accumulating evidence emphasizes the relevance of HA...
Gao, Yuzhen, He, Yan, Ding, Jun, Wu, Kang, Hu, Bo, Liu, Yang, ...
Hepatocellular carcinoma (HCC) is the fifth most common malignancy caused by environmental and genetic factors. MicroRNAs (miRNAs) are a class of short non-coding RNAs with posttranscriptional...
Polymorphisms within micro-RNA-binding sites and risk of sporadic colorectal cancer (2008)
Landi, Debora, Gemignani, Federica, Naccarati, Alessio, Pardini, Barbara, Vodicka, Pavel, Vodickova, Ludmila, ...
Recent evidence indicate that small non-coding RNA molecules, called micro-RNAs (miRNAs), can bind to the 3′ untranslated regions (UTRs) of messenger RNAs and interfere with their translation,...
Development of lung cancer before the age of 50: the role of xenobiotic metabolizing genes (2007)
Gemignani, Federica, Landi, Stefano, Szeszenia-Dabrowska, Neonilia, Zaridze, David, Lissowska, Jolanta, Rudnai, Peter, ...
The role of genes coding for xenobiotic metabolizing enzymes (XMEs) and the risk of lung cancer is unclear. Under the assumption that these genes may be more important among people having a diagnosis...
Gheit, Tarik, Billoud, Gaëlle, De Koning, Maurits N C, Gemignani, Federica, Forslund, Ola, Sylla, Bakary S, ...
Abstract is not available
Development of lung cancer before the age of 50: the role of xenobiotic metabolism genes (2007)
Gemignani, Federica, Landi, Stefano, Szeszenia-Dabrowska, Neonilia, Zaridze, David, Lissowska, Jolanta, Rudnai, Peter, ...
Objectives The role of genes coding for xenobiotic metabolism enzymes (XME) and the risk of lung cancer is unclear. Under the assumption that these genes may be more important among people having a...
Polymorphisms within inflammatory genes and colorectal cancer (2006)
Landi, Stefano, Gemignani, Federica, Bottari, Fabio, Gioia-Patricola, Lydie, Guino, Elisabet, Cambray, María, ...
Abstract Background Chronic inflammation is a risk factor for colorectal cancer and polymorphisms in the inflammatory genes could modulate the levels of inflammation. We have investigated ten single...
Landi, Stefano, Hanley, Nancy M., Warren, Sarah H., Pegram, Rex A., DeMarini, David M.
The brominated trihalomethanes (THMs) are mutagenic and carcinogenic disinfection by-products frequently found in chlorinated drinking water. They can be activated to mutagens by the product of the...
Landi, Stefano, Barale, Roberto
Our study looked at the variation in peripheral blood lymphocytes, during the menstrual cycle, of frequencies of sister chromatid exchanges (SCE) and micronuclei (MN) in 819 women and cells with...
Landi, Stefano, Ponzanelli, Isabella, Cipollini, Genziana, Frenzilli, Giada, Luccini, Antonella, Milillo, Caterina Paola, ...
Peripheral blood lymphocytes from a sample of 62 randomly selected donors were analysed for spontaneous and diepoxybutane (DEB)-induced chromosomal aberrations (CA). These individuals were part of a...
The nature of high frequency sister chromatid exchange cells (HFCs) (1997)
Ponzanelli, Isabella, Landi, Stefano, Bernacchi, Francesca, Barale, Roberto
We employed the three-way differential staining technique (TWD), which allows SCEs to be distinguished on a per generation basis by scoring third metaphases (M3), in order to study the spontaneous...
Gheit, Tarik, Landi, Stefano, Gemignani, Federica, Snijders, Peter J. F., Vaccarella, Salvatore, Franceschi, Silvia, ...
The importance of assays for the detection and typing of human papillomaviruses (HPVs) in clinical and epidemiological studies has been well demonstrated. Several accurate methods for HPV detection...
Polymorphisms within inflammatory genes and colorectal cancer
Landi, Stefano, Gemignani, Federica, Bottari, Fabio, Gioia-Patricola, Lydie, Guino, Elisabet, Cambray, María, ...
Gheit, Tarik, Landi, Stefano, Gemignani, Federica, Snijders, Peter J. F., Vaccarella, Salvatore, Franceschi, Silvia, ...
The importance of assays for the detection and typing of human papillomaviruses (HPVs) in clinical and epidemiological studies has been well demonstrated. Several accurate methods for HPV detection...
Polymorphisms within inflammatory genes and colorectal cancer
Landi, Stefano, Gemignani, Federica, Bottari, Fabio, Gioia-Patricola, Lydie, Guino, Elisabet, Cambray, María, ...
Gheit, Tarik, Billoud, Gaëlle, De Koning, Maurits N. C., Gemignani, Federica, Forslund, Ola, Sylla, Bakary S., ...
Emerging lines of evidence indicate that the cutaneous human papillomavirus (HPV) types that belong to the genus Betapapillomavirus (beta HPV) are involved in the development of nonmelanoma skin...
Campa, Daniele, Tavanti, Arianna, Gemignani, Federica, Mogavero, Crocifissa S., Bellini, Ilaria, Bottari, Fabio, ...
An oligonucleotide microarray based on the arrayed-primer extension (APEX) technique has been developed to simultaneously identify pathogenic fungi frequently isolated from invasive and superficial...
Garritano, Sonia, Gemignani, Federica, Voegele, Catherine, Nguyen-Dumont, Tú, Le Calvez-Kelm, Florence, De Silva, Deepika, ...