Stephan Ehrhardt

Artemether–lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria (2009)

Ehrhardt, Stephan

Stephan Ehrhardt, Christian G MeyerBernhard Nocht Institute for Tropical Medicine, Tropical Medicine Section, Hamburg, GermanyAbstract: The World Health Organization strongly recommends...

Sickle cell trait (HbAS) and stunting in children below two years of age in an area of high malaria transmission (2009)

Kreuels, Benno, Ehrhardt, Stephan, Kreuzberg, Christina, Adjei, Samuel, Kobbe, Robin, Burchard, Gerd D, ...

Abstract Background While the protective effects of sickle cell trait (HbAS) against severe malaria and the resulting survival advantage are well known, the impact on the physical development in...

Concurrence of Plasmodium falciparum dhfrand crtmutations in northern Ghana (2005)

Mockenhaupt, Frank P, Bousema, J Teun, Eggelte, Teunis A, Ehrhardt, Stephan, Otchwemah, Rowland N, Sauerwein, Robert W, ...

Abstract Background Both chloroquine (CQ) and sulfadoxine-pyrimethamine (SP) are failing drugs in much of sub-Saharan Africa. Previous findings suggest an association between resistance to CQ and to...

Allelic dimorphism of the erythocyte binding antigen-175 (eba-175) gene of Plasmodium falciparumand severe malaria: Significant association of the C-segment with fatal outcome in Ghanaian children (2004)

Cramer, Jakob P, Mockenhaupt, Frank P, Möhl, Ingo, Dittrich, Sabine, Dietz, Ekkehardt, Otchwemah, Rowland N, ...

Abstract Background The erythrocyte binding antigen-175 (EBA-175) on Plasmodium falciparum merozoites mediates sialic acid dependent binding to glycophorin A on host erythrocytes and, therefore,...

Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria

Mockenhaupt, Frank P., Cramer, Jakob P., Hamann, Lutz, Stegemann, Miriam S., Eckert, Jana, Oh, Na-Ri, ...

Genetic host factors play a substantial role in susceptibility to and severity of malaria, which continues to cause at least one million deaths per year. Recently, members of the toll-like receptor...

Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria

Mockenhaupt, Frank P., Cramer, Jakob P., Hamann, Lutz, Stegemann, Miriam S., Eckert, Jana, Oh, Na-Ri, ...

Genetic host factors play a substantial role in susceptibility to and severity of malaria, which continues to cause at least one million deaths per year. Recently, members of the toll-like receptor...

Large-Scale Surveillance of Plasmodium falciparum crt(K76T) in Northern Ghana▿

Ehrhardt, Stephan, Eggelte, Teunis A., Kaiser, Sarah, Adjei, Lydia, Burchard, Gerd D., Anemana, Sylvester D., ...

Surveillance of Plasmodium falciparum crt(K76T) [Pfcrt(K76T)], a resistance marker of chloroquine and, limitedly, amodiaquine, in >4,000 children in northern Ghana revealed a prevalence of 79%....

Artemether–lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria

Ehrhardt, Stephan, Meyer, Christian G

The World Health Organization strongly recommends artemisinin-based combination therapy (ACT) regimens for the treatment of uncomplicated Plasmodium falciparum malaria cases in endemic areas. Among...