Sleep deprivation and Pavlovian fear conditioning (2009)
Cai, Denise J., Shuman, Tristan, Harrison, Elizabeth M., Sage, Jennifer R., Anagnostaras, Stephan G.
Sleep has been suggested to play a role in memory consolidation. Prior rodent studies have used sleep deprivation to examine this relationship. First, we reexamined the effects of sleep deprivation...
Sage, Jennifer R., Anagnostaras, Stephan G., Mitchell, Shawn, Bronstein, Jeff M., De Salles, Antonio, Masterman, Donna, ...
This study examined the characteristics of probabilistic classification learning, a form of implicit learning previously shown to be impaired in patients with basal ganglia dysfunction (e.g.,...
Computer-Assisted Behavioral Assessment of Pavlovian Fear Conditioning in Mice (2000)
Anagnostaras, Stephan G., Josselyn, Sheena A., Frankland, Paul W., Silva, Alcino J.
Scopolamine and Pavlovian fear conditioning in rats: dose-effect analysis (1999)
Anagnostaras, Stephan G., Maren, Stephen, Sage, Jennifer R., Goodrich, Stacy, Fanselow, Michael S.
Muscarinic-cholinergic antagonism produces learning and memory deficits in a wide variety of hippocampal-dependent tasks. Hippocampal lesions produce both acquisition deficits and retrograde amnesia...
Anagnostaras, Stephan G., Maren, Stephen, Fanselow, Michael S.
We have shown previously that electrolytic lesions of the dorsal hippocampus (DH) produce a severe deficit in contextual fear if made 1 d, but not 28 d, after fear conditioning (). As such, the...
Anagnostaras, Stephan G., Maren, Stephen, DeCola, Joseph P., Lane, Nathan I., Gale, Greg D., Schlinger, Barney A., ...
We recently reported that Pavlovian fear conditioning and hippocampal perforant-path long-term potentiation (LTP) are sexually dimorphic in rats. Males show greater contextual fear conditioning,...
The startled seahorse: is the hippocampus necessary for contextual fear conditioning? (1998)
Maren, Stephen, Anagnostaras, Stephan G., Fanselow, Michael S.
Peer Reviewed
Kim, Jeansok J., Shih, Jean C., Chen, Kevin, Chen, Lu, Bao, Shaowen, Maren, Stephen, ...
Mice deficient in monoamine oxidase A (MAOA), an enzyme that metabolizes monoamines such as norepinephrine and serotonin, have elevated norepinephrine and serotonin levels in the frontal cortex,...
Scopolamine selectively disrupts the acquisition of contextual fear conditioning in rats (1995)
Anagnostaras, Stephan G., Maren, Stephen, Fanselow, Michael S.
Muscarinic cholinergic antagonism produces learning and memory deficits in a variety of hippocampal-dependent tasks. Hippocampal lesions produce both acquisition deficits and retrograde amnesia for...
Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice
Kim, Jeansok J., Shih, Jean C., Chen, Kevin, Chen, Lu, Bao, Shaowen, Maren, Stephen, ...
Mice deficient in monoamine oxidase A (MAOA), an enzyme that metabolizes monoamines such as norepinephrine and serotonin, have elevated norepinephrine and serotonin levels in the frontal cortex,...
Mihalek, Robert M., Banerjee, Pradeep K., Korpi, Esa R., Quinlan, Joseph J., Firestone, Leonard L., Mi, Zhi-Ping, ...
γ-Aminobutyric acid (GABA) type A receptors mediate fast inhibitory synaptic transmission and have been implicated in responses to sedative/hypnotic agents (including neuroactive steroids), anxiety,...
Deficits in memory and motor performance in synaptotagmin IV mutant mice
Ferguson, Gregory D., Anagnostaras, Stephan G., Silva, Alcino J., Herschman, Harvey R.
Synaptotagmin (Syt) IV is a synaptic vesicle protein. Syt IV expression is induced in the rat hippocampus after systemic kainic acid treatment. To examine the functional role of this protein in vivo,...
Sage, Jennifer R., Anagnostaras, Stephan G., Mitchell, Shawn, Bronstein, Jeff M., De Salles, Antonio, Masterman, Donna, ...
This study examined the characteristics of probabilistic classification learning, a form of implicit learning previously shown to be impaired in patients with basal ganglia dysfunction (e.g.,...
Computer-Assisted Behavioral Assessment of Pavlovian Fear Conditioning in Mice
Anagnostaras, Stephan G., Josselyn, Sheena A., Frankland, Paul W., Silva, Alcino J.
In Pavlovian fear conditioning, a conditional stimulus (CS, usually a tone) is paired with an aversive unconditional stimulus (US, usually a foot shock) in a novel context. After even a single...
Selective enhancement of emotional, but not motor, learning in monoamine oxidase A-deficient mice
Kim, Jeansok J., Shih, Jean C., Chen, Kevin, Chen, Lu, Bao, Shaowen, Maren, Stephen, ...
Mice deficient in monoamine oxidase A (MAOA), an enzyme that metabolizes monoamines such as norepinephrine and serotonin, have elevated norepinephrine and serotonin levels in the frontal cortex,...
Mihalek, Robert M., Banerjee, Pradeep K., Korpi, Esa R., Quinlan, Joseph J., Firestone, Leonard L., Mi, Zhi-Ping, ...
γ-Aminobutyric acid (GABA) type A receptors mediate fast inhibitory synaptic transmission and have been implicated in responses to sedative/hypnotic agents (including neuroactive steroids), anxiety,...
Deficits in memory and motor performance in synaptotagmin IV mutant mice
Ferguson, Gregory D., Anagnostaras, Stephan G., Silva, Alcino J., Herschman, Harvey R.
Synaptotagmin (Syt) IV is a synaptic vesicle protein. Syt IV expression is induced in the rat hippocampus after systemic kainic acid treatment. To examine the functional role of this protein in vivo,...
Sage, Jennifer R., Anagnostaras, Stephan G., Mitchell, Shawn, Bronstein, Jeff M., De Salles, Antonio, Masterman, Donna, ...
This study examined the characteristics of probabilistic classification learning, a form of implicit learning previously shown to be impaired in patients with basal ganglia dysfunction (e.g.,...
Computer-Assisted Behavioral Assessment of Pavlovian Fear Conditioning in Mice
Anagnostaras, Stephan G., Josselyn, Sheena A., Frankland, Paul W., Silva, Alcino J.
In Pavlovian fear conditioning, a conditional stimulus (CS, usually a tone) is paired with an aversive unconditional stimulus (US, usually a foot shock) in a novel context. After even a single...
A High Through-Put Reverse Genetic Screen Identifies Two Genes Involved in Remote Memory in Mice
Matynia, Anna, Anagnostaras, Stephan G., Wiltgen, Brian J., Lacuesta, Maress, Fanselow, Michael S., Silva, Alcino J.
Previous studies have revealed that the initial stages of memory formation require several genes involved in synaptic, transcriptional and translational mechanisms. In contrast, very little is known...