Stephan Schmidt

Motility and Force Generation Based on the Dynamics of Actin Gels (2009)

Schmidt, Stephan

This thesis explores the force generation of actin gels and their famous pro-pulsion mechanism leading to active motility on the cellular scale. In nature the generation of force and motility is...

Collaborative Filtering using Electrical Resistance Network Models with Negative Edges (2008)

Jérôme Kunegis, Stephan Schmidt

Abstract. In a recommender system where users rate items we predict the rating of items users have not rated. We define a rating graph containing users and items as vertices and ratings as weighted...

Entwicklung von Zweikomponentenverfahren für die nichtdispersive IR-Spektroskopie (NDIR) mit Hilfe von chemometrischen Methoden (2007)

Schmidt, Stephan

Spectroscopical procedures are well proven over years analysing solids, fluids and gaseous substances because of their high selectivity, sensitivity and their short response time. They allow...

Einfluss der Endothelinrezeptorblockade auf kardiale Funktion und Infarktgröße im akuten Ischämie-Reperfusionsmodell am Kaninchenherzen (2007)

Schmidt, Stephan

In einem etablierten Ischämie-Reperfusionsmodell wurde an in-vivo Kaninchenherzen die Auswirkung einer ETA- oder ETB-Rezeptorblockade während und direkt nach einer 60-min Myokardischämie...

Penetration of ertapenem into skeletal muscle and subcutaneous adipose tissue in healthy volunteers measured by in vivo microdialysis (2006)

Burkhardt, Olaf, Brunner, Martin, Schmidt, Stephan, Grant, Maria, Tang, Yufei, Derendorf, Hartmut

Objectives: Ertapenem is FDA approved for the treatment of skin and skin-structure infections (SSSI), but its in vivo penetration into the interstitial space of soft tissues is unknown. The present...

Penetration of ertapenem into skeletal muscle and subcutaneous adipose tissue in healthy volunteers measured by in vivo microdialysis (2006)

Burkhardt, Olaf, Brunner, Martin, Schmidt, Stephan, Grant, Maria, Tang, Yufei, Derendorf, Hartmut

Objectives: Ertapenem is FDA approved for the treatment of skin and skin-structure infections (SSSI), but its in vivo penetration into the interstitial space of soft tissues is unknown. The present...

Entwicklung von Zweikomponentenverfahren für die nichtdispersive IR-Spektroskopie (NDIR) mit Hilfe von chemometrischen Methoden (2005)

Schmidt, Stephan

Spectroscopical procedures are well proven over years analysing solids, fluids and gaseous substances because of their high selectivity, sensitivity and their short response time. They allow...

Entwicklung von Zweikomponentenverfahren für die nichtdispersive IR-Spektroskopie (NDIR) mit Hilfe von chemometrischen Methoden - Development of a two-component procedure for nondispersive infrared spectroscopy by chemometric methods (2003)

Schmidt, Stephan

Spectroscopical procedures are well proven over years analysing solids, fluids and gaseous substances because of their high selectivity, sensitivity and their short response time. They allow...

Entwicklung von Zweikomponentenverfahren für die nichtdispersive IR-Spektroskopie (NDIR) mit Hilfe von chemometrischen Methoden - Development of a two-component procedure for nondispersive infrared spectroscopy by chemometric methods (2003)

Schmidt, Stephan

Spectroscopical procedures are well proven over years analysing solids, fluids and gaseous substances because of their high selectivity, sensitivity and their short response time. They allow...

Are we regionalized enough? Early-neonatal deaths in low-risk births by the size of delivery units in Hesse, Germany 1990-1999 (2002)

Heller, Günther, Richardson, Douglas K, Schnell, Rainer, Misselwitz, Björn, Künzel, Wolfgang, Schmidt, Stephan

Background While agreement exists about the benefits of regionalization for high-risk births, little evidence exists regarding regionalization of low-risk births. The objective of this study was to...

Repertoire dynamics of autoreactive T cells in multiple sclerosis patients and healthy subjects: Epitope spreading versus clonal persistence (2000)

Goebels, Norbert, Hofstetter, Harald, Schmidt, Stephan, Brunner, Christoph, Wekerle, Hartmut, Hohlfeld, Reinhard

Autoantigen-specific T-lymphocytes are present in patients with autoimmune disease and in normal subjects. Little is currently known about the temporal variation (dynamics) of the immune repertoire...

Multiple sclerosis: Brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood

Skulina, Christian, Schmidt, Stephan, Dornmair, Klaus, Babbe, Holger, Roers, Axel, Rajewsky, Klaus, ...

We surveyed the T cell receptor repertoire in three separate compartments (brain, cerebrospinal fluid, and blood) of two multiple sclerosis patients who initially had diagnostic brain biopsies to...

Multiple sclerosis: Brain-infiltrating CD8+ T cells persist as clonal expansions in the cerebrospinal fluid and blood

Skulina, Christian, Schmidt, Stephan, Dornmair, Klaus, Babbe, Holger, Roers, Axel, Rajewsky, Klaus, ...

We surveyed the T cell receptor repertoire in three separate compartments (brain, cerebrospinal fluid, and blood) of two multiple sclerosis patients who initially had diagnostic brain biopsies to...

Clonal Expansions of Cd8+ T Cells Dominate the T Cell Infiltrate in Active Multiple Sclerosis Lesions as Shown by Micromanipulation and Single Cell Polymerase Chain Reaction

Babbe, Holger, Roers, Axel, Waisman, Ari, Lassmann, Hans, Goebels, Norbert, Hohlfeld, Reinhard, ...

Clonal composition and T cell receptor (TCR) repertoire of CD4+ and CD8+ T cells infiltrating actively demyelinating multiple sclerosis (MS) lesions were determined with unprecedented resolution at...

Effect of Protein Binding on the Pharmacological Activity of Highly Bound Antibiotics▿

Schmidt, Stephan, Röck, Katharina, Sahre, Martina, Burkhardt, Olaf, Brunner, Martin, Lobmeyer, Maximilian T., ...

During antibiotic drug development, media are frequently spiked with either serum/plasma or protein supplements to evaluate the effect of protein binding. Usually, previously reported serum or plasma...