Flibotte, Stephane, Moerman, Donald G
Abstract Background Microarray comparative genomic hybridization (CGH) is currently one of the most powerful techniques to measure DNA copy number in large genomes. In humans, microarray CGH is...
Stephane Flibotte, Readman Chiu, Chris Fjell, Martin Krzywinski, Jacqueline E, Heesun Shin, ...
Motivation: A considerable amount of human intervention is currently required to produce high quality fingerprint based physical maps for genomic studies. Results: An algorithm has been developed and...
Transcription of foreign DNA in Escherichia coli (2008)
Warren, René L., Freeman, John D., Levesque, Roger C., Smailus, Duane E., Flibotte, Stephane, Holt, Robert A.
Propagation of heterologous DNA in E. coli host cells is central to molecular biology. DNA constructs are often engineered for expression of recombinant protein in E. coli, but the extent of...
Jones, Martin R, Maydan, Jason S, Flibotte, Stephane, Moerman, Donald G, Baillie, David L
Abstract Background: A collection of genetic deficiencies covering over 70% of the Caenorhabditis elegans genome exists, however the application of these valuable biological tools has been limited...
Baross, Ágnes, Delaney, Allen D, Li, H Irene, Nayar, Tarun, Flibotte, Stephane, Qian, Hong, ...
Abstract Background Genomic deletions and duplications are important in the pathogenesis of diseases, such as cancer and mental retardation, and have recently been shown to occur frequently in...
Maydan, Jason S., Flibotte, Stephane, Edgley, Mark L., Lau, Joanne, Selzer, Rebecca R., Richmond, Todd A., ...
We have developed array Comparative Genomic Hybridization for Caenorhabditis elegans as a means of screening for novel induced deletions in this organism. We designed three microarrays consisting of...
Wilson, Gary M., Flibotte, Stephane, Chopra, Vikramjit, Melnyk, Brianna L., Honer, William G., Holt, Robert A.
Using bacterial artificial chromosome (BAC) array comparative genome hybridization (aCGH) at ∼1.4 Mbp resolution, we screened post-mortem brain DNA from bipolar disorder cases, schizophrenia cases...
Wilson, Gary M., Flibotte, Stephane, Chopra, Vikramjit, Melnyk, Brianna L., Honer, William G., Holt, Robert A.
Using bacterial artificial chromosome (BAC) array comparative genome hybridization (aCGH) at ∼1.4 Mbp resolution, we screened post-mortem brain DNA from bipolar disorder cases, schizophrenia...
Wilson, Gary M., Flibotte, Stephane, Missirlis, Perseus I., Marra, Marco A., Jones, Steven, Thornton, Kevin, ...
Duplication of chromosomal segments and associated genes is thought to be a primary mechanism for generating evolutionary novelty. By comparative genome hybridization using a full-coverage (tiling)...
Automated ordering of fingerprinted clones (2004)
Flibotte, Stephane, Chiu, Readman, Fjell, Chris, Krzywinski, Martin, Schein, Jacqueline E., Shin, Heesun, ...
Motivation: A considerable amount of human intervention is currently required to produce high quality fingerprint based physical maps for genomic studies. Results: An algorithm has been developed and...
Automated ordering of fingerprinted clones (2004)
Flibotte, Stephane, Chiu, Readman, Fjell, Chris, Krzywinski, Martin, Schein, Jacqueline E., Shin, Heesun, ...
Motivation: A considerable amount of human intervention is currently required to produce high-quality fingerprint-based physical maps for genomic studies. Results: An algorithm has been developed and...
Automated ordering of fingerprinted clones (2004)
Flibotte, Stephane, Chiu, Readman, Fjell, Chris, Krzywinski, Martin, Schein, Jacqueline E., Shin, Heesun, ...
Motivation: A considerable amount of human intervention is currently required to produce high quality fingerprint based physical maps for genomic studies. Results: An algorithm has been developed and...
Wilson, Gary M., Flibotte, Stephane, Missirlis, Perseus I., Marra, Marco A., Jones, Steven, Thornton, Kevin, ...
Duplication of chromosomal segments and associated genes is thought to be a primary mechanism for generating evolutionary novelty. By comparative genome hybridization using a full-coverage (tiling)...
Wilson, Gary M., Flibotte, Stephane, Missirlis, Perseus I., Marra, Marco A., Jones, Steven, Thornton, Kevin, ...
Duplication of chromosomal segments and associated genes is thought to be a primary mechanism for generating evolutionary novelty. By comparative genome hybridization using a full-coverage (tiling)...
Oligonucleotide Microarray Analysis of Genomic Imbalance in Children with Mental Retardation
Friedman, J. M., Baross, Ágnes, Delaney, Allen D., Ally, Adrian, Arbour, Laura, Asano, Jennifer, ...
The cause of mental retardation in one-third to one-half of all affected individuals is unknown. Microscopically detectable chromosomal abnormalities are the most frequently recognized cause, but...
Maydan, Jason S., Flibotte, Stephane, Edgley, Mark L., Lau, Joanne, Selzer, Rebecca R., Richmond, Todd A., ...
We have developed array Comparative Genomic Hybridization for Caenorhabditis elegans as a means of screening for novel induced deletions in this organism. We designed three microarrays consisting of...
Flibotte, Stephane, Edgley, Mark L., Maydan, Jason, Taylor, Jon, Zapf, Rick, Waterston, Robert, ...
We have developed a significantly improved and simplified method for high-resolution mapping of phenotypic traits in Caenorhabditis elegans using a combination of single nucleotide polymorphisms...
Transcription of foreign DNA in Escherichia coli
Warren, René L., Freeman, John D., Levesque, Roger C., Smailus, Duane E., Flibotte, Stephane, Holt, Robert A.
Propagation of heterologous DNA in E. coli host cells is central to molecular biology. DNA constructs are often engineered for expression of recombinant protein in E. coli, but the extent of...
Maydan, Jason S., Okada, H. Mark, Flibotte, Stephane, Edgley, Mark L., Moerman, Donald G.
Array comparative genomic hybridization (aCGH) has been used primarily to detect copy-number variants between two genomes. Here we report using aCGH to detect single nucleotide mutations on...
O'Meara, M. Maggie, Bigelow, Henry, Flibotte, Stephane, Etchberger, John F., Moerman, Donald G., Hobert, Oliver
We apply here comparative genome hybridization as a novel tool to identify the molecular lesion in two Caenorhabditis elegans mutant strains that affect a neuronal cell fate decision. The phenotype...