Stephanie Pack

Transduction of rat pancreatic islets with pseudotyped adeno-associated virus vectors (2009)

Craig, Anthony T, Gavrilova, Oksana, Dwyer, Nancy K, Jou, William, Pack, Stephanie, Liu, Eric, ...

Abstract Background Pancreatic islet transplantation is a promising treatment for type I diabetes mellitus, but current immunosuppressive strategies do not consistently provide long-term survival of...

Mammalian linker-histone subtypes differentially affect gene expression in vivo

Alami, Raouf, Fan, Yuhong, Pack, Stephanie, Sonbuchner, Timothy M., Besse, Arnaud, Lin, Qingcong, ...

Posttranslational modifications and remodeling of nucleosomes are critical factors in the regulation of transcription. Higher-order folding of chromatin also is likely to contribute to the control of...

Increased glucose tolerance and reduced adiposity in the absence of fasting hypoglycemia in mice with liver-specific Gsα deficiency

Chen, Min, Gavrilova, Oksana, Zhao, Wei-Qin, Nguyen, Annie, Lorenzo, Javier, Shen, Laura, ...

The G protein Gsα is essential for hormone-stimulated cAMP generation and is an important metabolic regulator. We investigated the role of liver Gs-signaling pathways by developing mice with...

Mammalian linker-histone subtypes differentially affect gene expression in vivo

Alami, Raouf, Fan, Yuhong, Pack, Stephanie, Sonbuchner, Timothy M., Besse, Arnaud, Lin, Qingcong, ...

Posttranslational modifications and remodeling of nucleosomes are critical factors in the regulation of transcription. Higher-order folding of chromatin also is likely to contribute to the control of...

Increased glucose tolerance and reduced adiposity in the absence of fasting hypoglycemia in mice with liver-specific Gsα deficiency

Chen, Min, Gavrilova, Oksana, Zhao, Wei-Qin, Nguyen, Annie, Lorenzo, Javier, Shen, Laura, ...

The G protein Gsα is essential for hormone-stimulated cAMP generation and is an important metabolic regulator. We investigated the role of liver Gs-signaling pathways by developing mice with...

Hypertrophy and/or Hyperplasia: Dynamics of Adipose Tissue Growth

Jo, Junghyo, Gavrilova, Oksana, Pack, Stephanie, Jou, William, Mullen, Shawn, Sumner, Anne E., ...

Adipose tissue grows by two mechanisms: hyperplasia (cell number increase) and hypertrophy (cell size increase). Genetics and diet affect the relative contributions of these two mechanisms to the...