Stephanie Reignat

Longitudinal Analysis of CD8+ T Cells Specific for Structural and Nonstructural Hepatitis B Virus Proteins in Patients with Chronic Hepatitis B: Implications for Immunotherapy

Webster, George J. M., Reignat, Stephanie, Brown, David, Ogg, Graham S., Jones, Louise, Seneviratne, Suranjith L., ...

The cytotoxic T-cell response in chronic hepatitis B virus (HBV) infection has been described as weak and mono- or oligospecific in comparison to the more robust virus-specific T-cell response...

Longitudinal Analysis of CD8+ T Cells Specific for Structural and Nonstructural Hepatitis B Virus Proteins in Patients with Chronic Hepatitis B: Implications for Immunotherapy

Webster, George J. M., Reignat, Stephanie, Brown, David, Ogg, Graham S., Jones, Louise, Seneviratne, Suranjith L., ...

The cytotoxic T-cell response in chronic hepatitis B virus (HBV) infection has been described as weak and mono- or oligospecific in comparison to the more robust virus-specific T-cell response...

The Role of Virus-Specific Cd8+ Cells in Liver Damage and Viral Control during Persistent Hepatitis B Virus Infection

Maini, Mala K., Boni, Carolina, Lee, Chun Kyon, Larrubia, Juan R., Reignat, Stephanie, Ogg, Graham S., ...

Hepatitis B virus (HBV) is a noncytopathic virus, and the recognition of infected hepatocytes by HBV-specific CD8 cells has been assumed to be the central mechanism causing both liver damage and...

Escaping High Viral Load Exhaustion: CD8 Cells with Altered Tetramer Binding in Chronic Hepatitis B Virus Infection

Reignat, Stephanie, Webster, George J.M., Brown, David, Ogg, Graham S., King, Abigail, Seneviratne, Suranjith L., ...

Deletion, anergy, and a spectrum of functional impairments can affect virus-specific CD8 cells in chronic viral infections. Here we characterize a low frequency population of CD8 cells present in...