Bouwer, H. G. Archie, Bai, Ailin, Forman, James, Gregory, Stephen H., Wing, Edward J., Barry, Ronald A., ...
Subclinical infection of BALB/c mice with the intracellular bacterial pathogen Listeria monocytogenes results in the development of protective antilisterial immunity. L. monocytogenes can infect...
Fas (CD95)-Dependent Cell-Mediated Immunity to Listeria monocytogenes
Jensen, Eric R., Glass, Alison A., Clark, William R., Wing, Edward J., Miller, Jeff F., Gregory, Stephen H.
Two distinct and complementary pathways, one mediated by perforin and the other dependent upon CD95 (Fas), effect cell-mediated cytotoxicity. We examined the relative roles of these pathways in host...
Host Resistance of CD18 Knockout Mice against Systemic Infection with Listeria monocytogenes
Wu, Huaizhu, Prince, Joseph E., Brayton, Cory F., Shah, Chirayu, Zeve, Daniel, Gregory, Stephen H., ...
Mice with targeted mutations of CD18, the common β2 subunit of CD11/CD18 integrins, have leukocytosis, impaired transendothelial neutrophil emigration, and reduced host defense to Streptococcus...
Bouwer, H. G. Archie, Bai, Ailin, Forman, James, Gregory, Stephen H., Wing, Edward J., Barry, Ronald A., ...
Subclinical infection of BALB/c mice with the intracellular bacterial pathogen Listeria monocytogenes results in the development of protective antilisterial immunity. L. monocytogenes can infect...
Fas (CD95)-Dependent Cell-Mediated Immunity to Listeria monocytogenes
Jensen, Eric R., Glass, Alison A., Clark, William R., Wing, Edward J., Miller, Jeff F., Gregory, Stephen H.
Two distinct and complementary pathways, one mediated by perforin and the other dependent upon CD95 (Fas), effect cell-mediated cytotoxicity. We examined the relative roles of these pathways in host...
Host Resistance of CD18 Knockout Mice against Systemic Infection with Listeria monocytogenes
Wu, Huaizhu, Prince, Joseph E., Brayton, Cory F., Shah, Chirayu, Zeve, Daniel, Gregory, Stephen H., ...
Mice with targeted mutations of CD18, the common β2 subunit of CD11/CD18 integrins, have leukocytosis, impaired transendothelial neutrophil emigration, and reduced host defense to Streptococcus...
Ayala, Alfred, Chung, Chun-Shiang, Lomas, Joanne L., Song, Grace Y., Doughty, Lesley A., Gregory, Stephen H., ...
Acute lung injury (ALI) leading to respiratory distress is a common sequela of shock/trauma, however, modeling this process in mice with a single shock or septic event is inconsistent. One...
In vivo delivery of caspase-8 or Fas siRNA improves the survival of septic mice
Wesche-Soldato, Doreen E., Chung, Chun-Shiang, Lomas-Neira, Joanne, Doughty, Lesley A., Gregory, Stephen H., Ayala, Alfred
Although studies have shown increased evidence of death receptor-driven apoptosis in intestinal lymphoid cells, splenocytes, and the liver following the onset of polymicrobial sepsis, little is known...
CD8+ T Cells Promote Inflammation and Apoptosis in the Liver after Sepsis : Role of Fas-FasL
Wesche-Soldato, Doreen E., Chung, Chun-Shiang, Gregory, Stephen H., Salazar-Mather, Thais P., Ayala, Carol A., Ayala, Alfred
Although studies blocking the Fas pathway indicate it can decrease organ damage while improving septic (cecal ligation and puncture, CLP) mouse survival, little is known about how Fas-Fas ligand...