Stephen Harris

Investigation of reproducibility of differentially expressed genes in DNA microarrays through statistical simulation (2009)

Fan, Xiaohui, Shi, Leming, Fang, Hong, Harris, Stephen, Perkins, Roger, Tong, Weida

Abstract Recent publications have raised concerns about the reliability of microarray technology because of the lack of reproducibility of differentially expressed genes (DEGs) from highly similar...

Behavioral changes associated with a population density decline in the facultatively social red fox (2009)

Iossa, Graziella, Soulsbury, Carl D., Baker, Philip J., Edwards, Keith J., Harris, Stephen

Understanding the causal mechanisms promoting group formation in carnivores has been widely investigated, particularly how fitness components affect group formation. Population density may affect the...

Body mass, territory size, and life-history tactics in a socially monogamous canid, the red fox Vulpes vulpes (2008)

Graziella Iossa, Carl D. Soulsbury, Philip J. Baker, Stephen Harris

Male-biased sexual size dimorphism is typical of polygynous mammals, where the degree of dimorphism in body mass is related to male intrasexual competition and the degree of polygyny. However, the...

Image annotation with Photocopain (2006)

Tuffield, Mischa, Harris, Stephen, Dupplaw, David P., Chakravarthy, Ajay, Brewster, Christopher, Gibbins, Nicholas, ...

Photo annotation is a resource-intensive task, yet is increasingly essential as image archives and personal photo collections grow in size. There is an inherent conflict in the process of describing...

Winnowing Ontologies based on Application Use (2006)

Alani, Harith, Harris, Stephen, O'Neil, Ben

The requirements of specific applications and services are often over estimated when ontologies are reused or built. This sometimes results in many ontologies being too large for their intended...

Image annotation with Photocopain (2006)

Tuffield, Mischa, Harris, Stephen, Dupplaw, David P., Chakravarthy, Ajay, Brewster, Christopher, Gibbins, Nicholas, ...

Photo annotation is a resource-intensive task, yet is increasingly essential as image archives and personal photo collections grow in size. There is an inherent conflict in the process of describing...

Winnowing Ontologies based on Application Use (2006)

Alani, Harith, Harris, Stephen, O'Neil, Ben

The requirements of specific applications and services are often over estimated when ontologies are reused or built. This sometimes results in many ontologies being too large for their intended...

Image annotation with Photocopain (2006)

Tuffield, Mischa M., Harris, Stephen, Duplaw, David P., Chakravarthy, Ajay, Brewester, Christopher, Gibbins, Nicholas, ...

Photo annotation is a resource-intensive task, yet is increasingly essential as image archives and personal photo collections grow in size. There is an inherent conflict in the process of describing...

Image annotation with Photocopain (2006)

Tuffield, Mischa, Harris, Stephen, Dupplaw, David P., Chakravarthy, Ajay, Brewster, Christopher, Gibbins, Nicholas, ...

Photo annotation is a resource-intensive task, yet is increasingly essential as image archives and personal photo collections grow in size. There is an inherent conflict in the process of describing...

Winnowing Ontologies based on Application Use (2006)

Alani, Harith, Harris, Stephen, O'Neil, Ben

The requirements of specific applications and services are often over estimated when ontologies are reused or built. This sometimes results in many ontologies being too large for their intended...

B.: Winnowing Ontologies Based on Application Use (2006)

Harith Alani, Stephen Harris

Abstract. The requirements of specific applications and services are often over estimated when ontologies are designed and built. This sometimes results in many ontologies being too large for their...

Image annotation with photocopain (2006)

Mischa M. Tuffield, Stephen Harris, Christopher Brewster, Nicholas Gibbins, Fabio Ciravegna, Derek Sleeman, ...

Abstract. Photo annotation is a resource-intensive task, yet is increasingly essential as image archives and personal photo collections grow in size. There is an inherent conflict in the process of...

B.: Winnowing Ontologies Based on Application Use (2006)

Harith Alani, Stephen Harris

Abstract. The requirements of specific applications and services are often over estimated when ontologies are reused or built. This sometimes results in many ontologies being too large for their...

Image annotation with photocopain (2006)

Mischa M. Tuffield, Stephen Harris, Christopher Brewster, Nicholas Gibbins, Fabio Ciravegna, Derek Sleeman, ...

Abstract. Photo annotation is a resource-intensive task, yet is increasingly essential as image archives and personal photo collections grow in size. There is an inherent conflict in the process of...

B.: Winnowing Ontologies Based on Application Use (2006)

Harith Alani, Stephen Harris

Abstract. The requirements of specific applications and services are often over estimated when ontologies are reused or built. This sometimes results in many ontologies being too large for their...

Monitoring Research Collaborations Using Semantic Web Technologies (2005)

Alani, Harith, Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen, Shadbolt, Nigel

In the current research environment, funding agencies are increasingly required to demonstrate that the projects they fund represent value for money. When funds are disbursed in a speculative manner,...

Monitoring Research Collaborations Using Semantic Web Technologies (2005)

Alani, Harith, Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen, Shadbolt, Nigel

In the current research environment, funding agencies are increasingly required to demonstrate that the projects they fund represent value for money. When funds are disbursed in a speculative manner,...

SPARQL query processing with conventional relational database systems (2005)

Harris, Stephen

This paper describes an evolution of the 3store RDF storage system, extended to provide a SPARQL query interface and informed by lessons learned in the area of scalable RDF storage.

Monitoring Research Collaborations Using Semantic Web Technologies (2005)

Alani, Harith, Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen, Shadbolt, Nigel

In the current research environment, funding agencies are increasingly required to demonstrate that the projects they fund represent value for money. When funds are disbursed in a speculative manner,...

SPARQL query processing with conventional relational database systems (2005)

Harris, Stephen

This paper describes an evolution of the 3store RDF storage system, extended to provide a SPARQL query interface and informed by lessons learned in the area of scalable RDF storage.

Monitoring Research Collaborations Using Semantic Web Technologies (2005)

Alani, Harith, Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen, Shadbolt, Nigel

In the current research environment, funding agencies are increasingly required to demonstrate that the projects they fund represent value for money. When funds are disbursed in a speculative manner,...

SPARQL query processing with conventional relational database systems (2005)

Harris, Stephen

This paper describes an evolution of the 3store RDF storage system, extended to provide a SPARQL query interface and informed by lessons learned in the area of scalable RDF storage.

Monitoring research collaborations using semantic web technologies (2005)

Harith Alani, Nicholas Gibbins, Hugh Glaser, Stephen Harris, Nigel Shadbolt

Abstract In the current research environment, funding agencies are increasingly required to demonstrate that the projects they fund represent value for money. When funds are disbursed in a...

Scragg, ed., Textual and Material Culture (Stephen Harris ) (2004)

Stephen Harris

Stephen Harris , University of Massachusetts, sharris@english.umass.edu

CS AKTiveSpace: Building a Semantic Web Application (2004)

Glaser, Hugh, Alani, Harith, Carr, Les, Chapman, Sam, Ciravegna, Fabio, Dingli, Alexiei, ...

In this paper we reflect on the lessons learned from deploying the award winning [1] Semantic Web application, CS AKTiveSpace. We look at issues in service orientation and modularisation, harvesting,...

CS AKTive Space: Representing Computer Science in the Semantic Web (2004)

Schraefel, M.c., Shadbolt, Nigel R, Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen

We present a Semantic Web application that we call CS AKTive Space1. The application exploits a wide range of semantically heterogeneous and distributed content relating to Computer Science research...

Walking Through CS AKTive Space: A demonstration of an integrated SemanticWeb Application (2004)

Shadbolt, Nigel R., Schraefel, M.c., Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen

We describe CS AKTive Space,an integrated Semantic Web application and winner of the 2003 Semantic Web Challenge [http://challenge.semanticweb.org/]. A demonstration of the application is available...

CS AKTive Space: Building a Semantic Web Application (2004)

Glaser, Hugh, Alani, Harith, Carr, Les, Chapman, Sam, Ciravegna, Fabio, Dingli, Alexei, ...

In this paper we reflect on the lessons learned from deploying the award winning [1] Semantic Web application, CS AKTiveSpace. We look at issues in service orientation and modularisation, harvesting,...

CS AKTive Space or how we stopped worrying and learned to love the Semantic Web (2004)

Shadbolt, Nigel R., Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen, Schraefel, M.c.

The mission of the Advanced Knowledge Technologies (AKT) project is to investigate how to operationalize the knowledge management mantra of "getting the right content to the right place at the right...

CS AKTive Space: Representing Computer Science in the Semantic Web (2004)

Schraefel, M.c., Shadbolt, Nigel R., Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen

We present a Semantic Web application that we call CS AKTive- Space. The application exploits a wide range of semantically heterogeneous and distributed content relating to Computer Science research...

Applying mSpace interfaces to the Semantic Web - working paper (2004)

Gibbins, Nicholas, Harris, Stephen, Dix, Alan, Schraefel, Mc

Ontologies can represent large, multidimensional spaces: classical music, research in computer science in the UK, health care for breast cancer are examples of rich domains. There have been no easy...

The Semantic Web as a Semantic Soup (2004)

Cox, Simon, Alani, Harith, Glaser, Hugh, Harris, Stephen

The Semantic Web is currently best known for adding metadata to web pages to allow computers to 'understand' what they contain. This idea has been applied to people by the Friend of a Friend project...

Walking Through CS AKTive Space: A demonstration of an integrated SemanticWeb Application (2004)

Shadbolt, Nigel R., Schraefel, M.c., Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen

We describe CS AKTive Space,an integrated Semantic Web application and winner of the 2003 Semantic Web Challenge [http://challenge.semanticweb.org/]. A demonstration of the application is available...

CS AKTive Space: Building a Semantic Web Application (2004)

Glaser, Hugh, Alani, Harith, Carr, Les, Chapman, Sam, Ciravegna, Fabio, Dingli, Alexei, ...

In this paper we reflect on the lessons learned from deploying the award winning [1] Semantic Web application, CS AKTiveSpace. We look at issues in service orientation and modularisation, harvesting,...

CS AKTive Space or how we stopped worrying and learned to love the Semantic Web (2004)

Shadbolt, Nigel R., Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen, Schraefel, M.c.

The mission of the Advanced Knowledge Technologies (AKT) project is to investigate how to operationalize the knowledge management mantra of "getting the right content to the right place at the right...

CS AKTive Space: Representing Computer Science in the Semantic Web (2004)

Schraefel, M.c., Shadbolt, Nigel R., Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen

We present a Semantic Web application that we call CS AKTive- Space. The application exploits a wide range of semantically heterogeneous and distributed content relating to Computer Science research...

Applying mSpace interfaces to the Semantic Web - working paper (2004)

Gibbins, Nicholas, Harris, Stephen, Dix, Alan, Schraefel, Mc

Ontologies can represent large, multidimensional spaces: classical music, research in computer science in the UK, health care for breast cancer are examples of rich domains. There have been no easy...

The Semantic Web as a Semantic Soup (2004)

Cox, Simon, Alani, Harith, Glaser, Hugh, Harris, Stephen

The Semantic Web is currently best known for adding metadata to web pages to allow computers to 'understand' what they contain. This idea has been applied to people by the Friend of a Friend project...

Walking Through CS AKTive Space: A demonstration of an integrated SemanticWeb Application (2004)

Shadbolt, Nigel R., Schraefel, M.c., Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen

We describe CS AKTive Space,an integrated Semantic Web application and winner of the 2003 Semantic Web Challenge [http://challenge.semanticweb.org/]. A demonstration of the application is available...

CS AKTive Space: Building a Semantic Web Application (2004)

Glaser, Hugh, Alani, Harith, Carr, Les, Chapman, Sam, Ciravegna, Fabio, Dingli, Alexei, ...

In this paper we reflect on the lessons learned from deploying the award winning [1] Semantic Web application, CS AKTiveSpace. We look at issues in service orientation and modularisation, harvesting,...

CS AKTive Space or how we stopped worrying and learned to love the Semantic Web (2004)

Shadbolt, Nigel R., Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen, Schraefel, M.c.

The mission of the Advanced Knowledge Technologies (AKT) project is to investigate how to operationalize the knowledge management mantra of "getting the right content to the right place at the right...

CS AKTive Space: Representing Computer Science in the Semantic Web (2004)

Schraefel, M.c., Shadbolt, Nigel R., Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen

We present a Semantic Web application that we call CS AKTive- Space. The application exploits a wide range of semantically heterogeneous and distributed content relating to Computer Science research...

Applying mSpace interfaces to the Semantic Web - working paper (2004)

Gibbins, Nicholas, Harris, Stephen, Dix, Alan, Schraefel, Mc

Ontologies can represent large, multidimensional spaces: classical music, research in computer science in the UK, health care for breast cancer are examples of rich domains. There have been no easy...

The Semantic Web as a Semantic Soup (2004)

Cox, Simon, Alani, Harith, Glaser, Hugh, Harris, Stephen

The Semantic Web is currently best known for adding metadata to web pages to allow computers to 'understand' what they contain. This idea has been applied to people by the Friend of a Friend project...

CS AKTive Space: Building a Semantic Web Application (2004)

Hugh Glaser, Harith Alani, Sam Chapman, Alexiei Dingli, Nicholas Gibbins, Stephen Harris, ...

In this paper we reflect on the lessons learned from deploying the award winning [1] Semantic Web application, CS AKTiveSpace. We look at issues in service orientation and modularisation, harvesting,...

CS AKTive Space, or how we learned to stop worrying and love the semantic Web (2004)

Nigel Shadbolt, Nicholas Gibbins, Hugh Glaser, Stephen Harris, M. C. Schraefel

(AKT) project is to investigate how to operationalise the knowledge management mantra of “getting the right content to the right place at the right time and in the right form. ” A significant...

Polygynandry in a red fox population: implications for the evolution of group living in canids? (2004)

Baker, Philip J., Funk, Stephan M., Bruford, Michael W., Harris, Stephen

Canid social groups are typically thought to consist of extended families, that is, a dominant breeding pair and related nonbreeding subordinates, that principally obtain indirect fitness benefits...

Polygynandry in a red fox population: implications for the evolution of group living in canids? (2004)

Baker, Philip J., Funk, Stephan M., Bruford, Michael W., Harris, Stephen

Canid social groups are typically thought to consist of extended families, that is, a dominant breeding pair and related nonbreeding subordinates, that principally obtain indirect fitness benefits...

3store: Efficient Bulk RDF Storage (2003)

Harris, Stephen, Gibbins, Nicholas

The development and deployment of practical Semantic Web applications requires technologies for the storage and retrieval of RDF data that are robust and scalable. In this paper, we describe the...

3store: Efficient Bulk RDF Storage (2003)

Harris, Stephen, Gibbins, Nicholas

The development and deployment of practical Semantic Web applications requires technologies for the storage and retrieval of RDF data that are robust and scalable. In this paper, we describe the...

3store: Efficient Bulk RDF Storage (2003)

Harris, Stephen, Gibbins, Nicholas

The development and deployment of practical Semantic Web applications requires technologies for the storage and retrieval of RDF data that are robust and scalable. In this paper, we describe the...

3store: Efficient Bulk RDF Storage (2003)

Harris, Stephen, Gibbins, Dr Nicholas

The development and deployment of practical Semantic Web applications requires technologies for the storage and retrieval of RDF data that are robust and scalable. In this paper, we describe the...

Agent-based Semantic Web Services (2003)

Gibbins, Nicholas, Harris, Stephen, Shadbolt, Nigel

The Web Services world consists of loosely-coupled distributed systems which adapt to ad-hoc changes by the use of service descriptions that enable opportunistic service discovery. At present, these...

CS AKTive Space: or How We Stopped Worrying and Learned to Love the Semantic Web (2003)

Shadbolt, Nigel R., Schraefel, Monica M.c., Gibbins, Nicholas, Harris, Stephen

Abstract. We present a Semantic Web application that we call CS AKTive Space. The application exploits a wide range of semantically heterogeneous and distributed content relating to Computer Science...

3store: Efficient Bulk RDF Storage (2003)

Harris, Stephen, Gibbins, Nicholas

The development and deployment of practical Semantic Web applications requires technologies for the storage and retrieval of RDF data that are robust and scalable. In this paper, we describe the...

CS AKTive Space: Representing Computer Science in the Semantic Web (2003)

Schraefel, M.c., Shadbolt, Nigel R., Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen

We present a Semantic Web application that we call CS AKTive- Space. The application exploits a wide range of semantically heterogeneous and distributed content relating to Computer Science research...

Applying mSpace Interfaces to the Semantic Web (2003)

Gibbins, Nicholas, Harris, Stephen, Schraefel, Monica

Ontologies can represent large, multidimensional spaces: classical music, research in computer science in the UK, health care for breast cancer are examples of rich domains. There have been no easy...

Agent-based Semantic Web Services (2003)

Gibbins, Nicholas, Harris, Stephen, Shadbolt, Nigel

The Web Services world consists of loosely-coupled distributed systems which adapt to changes by the use of service descriptions that enable ad-hoc, opportunistic service discovery and reuse. At...

CS AKTive Space: or How We Stopped Worrying and Learned to Love the Semantic Web (2003)

Shadbolt, Nigel R., Schraefel, Monica M.c., Gibbins, Nicholas, Harris, Stephen

Abstract. We present a Semantic Web application that we call CS AKTive Space. The application exploits a wide range of semantically heterogeneous and distributed content relating to Computer Science...

3store: Efficient Bulk RDF Storage (2003)

Harris, Stephen, Gibbins, Nicholas

The development and deployment of practical Semantic Web applications requires technologies for the storage and retrieval of RDF data that are robust and scalable. In this paper, we describe the...

CS AKTive Space: Representing Computer Science in the Semantic Web (2003)

Schraefel, M.c., Shadbolt, Nigel R., Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen

We present a Semantic Web application that we call CS AKTive- Space. The application exploits a wide range of semantically heterogeneous and distributed content relating to Computer Science research...

Applying mSpace Interfaces to the Semantic Web (2003)

Gibbins, Nicholas, Harris, Stephen, Schraefel, Monica

Ontologies can represent large, multidimensional spaces: classical music, research in computer science in the UK, health care for breast cancer are examples of rich domains. There have been no easy...

Agent-based Semantic Web Services (2003)

Gibbins, Nicholas, Harris, Stephen, Shadbolt, Nigel

The Web Services world consists of loosely-coupled distributed systems which adapt to changes by the use of service descriptions that enable ad-hoc, opportunistic service discovery and reuse. At...

CS AKTive Space: or How We Stopped Worrying and Learned to Love the Semantic Web (2003)

Shadbolt, Nigel R., Schraefel, Monica M.c., Gibbins, Nicholas, Harris, Stephen

Abstract. We present a Semantic Web application that we call CS AKTive Space. The application exploits a wide range of semantically heterogeneous and distributed content relating to Computer Science...

3store: Efficient Bulk RDF Storage (2003)

Harris, Stephen, Gibbins, Nicholas

The development and deployment of practical Semantic Web applications requires technologies for the storage and retrieval of RDF data that are robust and scalable. In this paper, we describe the...

CS AKTive Space: Representing Computer Science in the Semantic Web (2003)

Schraefel, M.c., Shadbolt, Nigel R., Gibbins, Nicholas, Glaser, Hugh, Harris, Stephen

We present a Semantic Web application that we call CS AKTive- Space. The application exploits a wide range of semantically heterogeneous and distributed content relating to Computer Science research...

Applying mSpace Interfaces to the Semantic Web (2003)

Gibbins, Nicholas, Harris, Stephen, Schraefel, Monica

Ontologies can represent large, multidimensional spaces: classical music, research in computer science in the UK, health care for breast cancer are examples of rich domains. There have been no easy...

Agent-based Semantic Web Services (2003)

Gibbins, Nicholas, Harris, Stephen, Shadbolt, Nigel

The Web Services world consists of loosely-coupled distributed systems which adapt to changes by the use of service descriptions that enable ad-hoc, opportunistic service discovery and reuse. At...

CS AKTive Space: or how we stopped worrying and learned to love the semantic web (2003)

Nigel R. Shadbolt, Nicholas Gibbins, Stephen Harris

Abstract. We present a Semantic Web application that we call CS AKTive Space. The application exploits a wide range of semantically heterogeneous and distributed content relating to Computer Science...

Applying mSpace Interfaces to the Semantic Web (2003)

Nicholas Gibbins, Stephen Harris, Alan Dix, M. C. Schraefel

Abstract. Ontologies can represent large, multidimensional spaces: classical

ArrayTrack--supporting toxicogenomic research at the U.S. Food and Drug Administration National Center for Toxicological Research. Environ Health Perspect 111 (2003)

Weida Tong, Xiaoxi Cao, Stephen Harris, Hongmei Sun, Hong Fang, James Fuscoe, ...

The mapping of the human genome and the determination of corresponding gene functions, pathways, and biological mechanisms are driving the emergence of the new research fields of toxicogenomics and...

3store: Efficient Bulk RDF Storage (2003)

Stephen Harris, Nicholas Gibbins

The development and deployment of practical Semantic Web applications requires technologies for the storage and retrieval of RDF data that are robust and scalable. In this paper, we describe the...

Using Advanced Intercross Lines for High-Resolution Mapping of HDL Cholesterol Quantitative Trait Loci (2003)

Wang, Xiaosong, Le Roy, Isabelle, Nicodeme, Edwige, Li, Renhua, Wagner, Richard, Petros, Christina, ...

Mapping quantitative trait loci (QTLs)with high resolution facilitates identification and positional cloning of the underlying genes. The novel approach of advanced intercross lines (AILs) generates...

Using Advanced Intercross Lines for High-Resolution Mapping of HDL Cholesterol Quantitative Trait Loci (2003)

Wang, Xiaosong, Le Roy, Isabelle, Nicodeme, Edwige, Li, Renhua, Wagner, Richard, Petros, Christina, ...

Mapping quantitative trait loci (QTLs)with high resolution facilitates identification and positional cloning of the underlying genes. The novel approach of advanced intercross lines (AILs) generates...

Proceedings of the Military Communications System Control Symposium, (2002)

Harris, Stephen, Heller, James

Contents: Perspective on Communications System Control, Navy Force Coordination and the Requirements for Communications Network Management, On the Functions of a Network Management Agency, Improved...

(fox, deer, hare and mink) populations, and its effectiveness (2002)

Stephen Harris

Session 2B: Method that causes least suffering in controlling the quarry species

The Need for an Internal Market Ombudsman (1999)

Harris, Stephen

[Foreword]. This article arises from private conversations with industry and other sources over the past 5 or so years about their general impressions of the workings of the European Union (EU)...

Enforcement in the Internal Market (1998)

Harris, Stephen

[From the Introduction]. A businesswoman in the USA telephoned the author in London late one evening a couple of years ago to complain that French Customs officials had seized a consignment of...

... Croup, or cynanche trachealis. (1819)

Harris, Stephen.

Thesis--University of Pennsylvania, 1819.

A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases

Yin, Juan Juan, Mohammad, Khalid S., Käkönen, Sanna M., Harris, Stephen, Wu-Wong, J. Ruth, Wessale, Jerry L., ...

Osteoblastic bone metastases are common in prostate and breast cancer patients, but mechanisms by which tumor cells stimulate new bone formation are unclear. We identified three breast cancer cell...

Using Advanced Intercross Lines for High-Resolution Mapping of HDL Cholesterol Quantitative Trait Loci

Wang, Xiaosong, Le Roy, Isabelle, Nicodeme, Edwige, Li, Renhua, Wagner, Richard, Petros, Christina, ...

Mapping quantitative trait loci (QTLs)with high resolution facilitates identification and positional cloning of the underlying genes. The novel approach of advanced intercross lines (AILs) generates...

ArrayTrack--supporting toxicogenomic research at the U.S. Food and Drug Administration National Center for Toxicological Research.

Tong, Weida, Cao, Xiaoxi, Harris, Stephen, Sun, Hongmei, Fang, Hong, Fuscoe, James, ...

The mapping of the human genome and the determination of corresponding gene functions, pathways, and biological mechanisms are driving the emergence of the new research fields of toxicogenomics and...

PRISM/PRDM6, a Transcriptional Repressor That Promotes the Proliferative Gene Program in Smooth Muscle Cells

Davis, Christopher A., Haberland, Michael, Arnold, Michael A., Sutherland, Lillian B., McDonald, Oliver G., Richardson, James A., ...

Smooth muscle cells (SMCs) display remarkable phenotypic diversity and plasticity and can readily switch between proliferative and differentiated states in response to extracellular cues. In an...

A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases

Yin, Juan Juan, Mohammad, Khalid S., Käkönen, Sanna M., Harris, Stephen, Wu-Wong, J. Ruth, Wessale, Jerry L., ...

Osteoblastic bone metastases are common in prostate and breast cancer patients, but mechanisms by which tumor cells stimulate new bone formation are unclear. We identified three breast cancer cell...

Using Advanced Intercross Lines for High-Resolution Mapping of HDL Cholesterol Quantitative Trait Loci

Wang, Xiaosong, Le Roy, Isabelle, Nicodeme, Edwige, Li, Renhua, Wagner, Richard, Petros, Christina, ...

Mapping quantitative trait loci (QTLs)with high resolution facilitates identification and positional cloning of the underlying genes. The novel approach of advanced intercross lines (AILs) generates...

ArrayTrack--supporting toxicogenomic research at the U.S. Food and Drug Administration National Center for Toxicological Research.

Tong, Weida, Cao, Xiaoxi, Harris, Stephen, Sun, Hongmei, Fang, Hong, Fuscoe, James, ...

The mapping of the human genome and the determination of corresponding gene functions, pathways, and biological mechanisms are driving the emergence of the new research fields of toxicogenomics and...

PRISM/PRDM6, a Transcriptional Repressor That Promotes the Proliferative Gene Program in Smooth Muscle Cells

Davis, Christopher A., Haberland, Michael, Arnold, Michael A., Sutherland, Lillian B., McDonald, Oliver G., Richardson, James A., ...

Smooth muscle cells (SMCs) display remarkable phenotypic diversity and plasticity and can readily switch between proliferative and differentiated states in response to extracellular cues. In an...

Investigation of reproducibility of differentially expressed genes in DNA microarrays through statistical simulation

Fan, Xiaohui, Shi, Leming, Fang, Hong, Harris, Stephen, Perkins, Roger, Tong, Weida

Recent publications have raised concerns about the reliability of microarray technology because of the lack of reproducibility of differentially expressed genes (DEGs) from highly similar studies...

Environmental variation at the onset of independent foraging affects full-grown body mass in the red fox

Soulsbury, Carl D, Iossa, Graziella, Baker, Philip J, Harris, Stephen

The period following the withdrawal of parental care has been highlighted as a key developmental period for juveniles. One reason for this is that juveniles cannot forage as competently as adults,...