Yosaatmadja, Francisca, Andrews, Katherine T, Duffy, Michael F, Brown, Graham V, Beeson, James G, Rogerson, Stephen J
Abstract Background Malaria in pregnancy is characterized by accumulation of infected erythrocytes (IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium falciparum...
Maternal–Fetal Microtransfusions and HIV-1 Mother-to-Child Transmission in Malawi (2006)
Jesse J. Kwiek, Victor Mwapasa, Danny A. Milner, Alisa P. Alker, William C. Miller, Eyob Tadesse, ...
Placental microtransfusions as measured by placental alkaline phosphatase levels in cord blood are a risk factor for mother-to-child transmission during vaginal deliveries.
Maternal–Fetal Microtransfusions and HIV-1 Mother-to-Child Transmission in Malawi (2006)
Jesse J. Kwiek, Victor Mwapasa, Danny A. Milner Jr., Alisa P. Alker, William C. Miller, Eyob Tadesse, ...
Background Between 25% and 35% of infants born to HIV-infected mothers become HIV-1 infected. One potential route of mother-to-child transmission (MTCT) could be through a breakdown in the placental...
Malaria during pregnancy and foetal haematological status in Blantyre, Malawi (2005)
Abrams, Elizabeth T., Kwiek, Jesse J., Mwapasa, Victor, Kamwendo, Deborah D., Tadesse, Eyob, Lema, Valentino M., ...
Background Although maternal anaemia often stems from malaria infection during pregnancy, its effects on foetal haemoglobin levels are not straightforward. Lower-than-expected cord haemoglobin values...
Malaria during pregnancy and foetal haematological status in Blantyre, Malawi (2005)
Abrams, Elizabeth T, Kwiek, Jesse J, Mwapasa, Victor, Kamwendo, Deborah D, Tadesse, Eyob, Lema, Valentino M, ...
Abstract Background Although maternal anaemia often stems from malaria infection during pregnancy, its effects on foetal haemoglobin levels are not straightforward. Lower-than-expected cord...
Cytoadherence and rosetting in Plasmodium falciparum (1995)
Typescript (photocopy) Includes bibliographical references (leaves 112-131)
Reeder, John C., Cowman, Alan F., Davern, Kathleen M., Beeson, James G., Thompson, Jennifer K., Rogerson, Stephen J., ...
Chondroitin sulfate A (CSA) is an important receptor for the sequestration of Plasmodium falciparum in the placenta, but the parasite ligand involved in adhesion has not previously been identified....
MacDonald, Susan M., Bhisutthibhan, Jamaree, Shapiro, Theresa A., Rogerson, Stephen J., Taylor, Terrie E., Tembo, Madalitso, ...
The Plasmodium falciparum translationally controlled tumor protein (TCTP) is a homolog of the mammalian histamine-releasing factor (HRF), which causes histamine release from human basophils and IL-8...
Plasmodium falciparum Rosette Formation Is Uncommon in Isolates from Pregnant Women
Rogerson, Stephen J., Beeson, James G., Mhango, Chisale G., Dzinjalamala, Fraction K., Molyneux, Malcolm E.
We examined the formation of Plasmodium falciparum erythrocyte rosettes using parasite isolates from placental or peripheral blood of pregnant Malawian women and from peripheral blood of children....
Beeson, James G., Chai, Wengang, Rogerson, Stephen J., Lawson, Alexander M., Brown, Graham V.
Adherence of parasite-infected erythrocytes (IEs) to the microvascular endothelium of various organs, a process known as sequestration, is a feature of Plasmodium falciparum malaria. This event is...
Mankhambo, Limangeni, Kanjala, Maxwell, Rudman, Sarah, Lema, Valentino M., Rogerson, Stephen J.
During pregnancy, Plasmodium falciparum infection of the placenta frequently occurs in the absence of parasites in peripheral blood. We investigated the abilities of the OptiMAL rapid...
Beeson, James G., Amin, Nishal, Kanjala, Maxwell, Rogerson, Stephen J.
A feature of malaria in pregnancy is accumulation of P. falciparum-infected erythrocytes (IEs) in the placenta, which is associated with adverse outcomes for mothers and infants. Infection appears to...
Rogerson, Stephen J., Brown, Heidi C., Pollina, Elena, Abrams, Elizabeth T., Tadesse, Eyob, Lema, Valentino M., ...
Malaria in pregnancy predisposes to maternal anemia and low birth weight (LBW). We examined the possible roles of the cytokines tumor necrosis factor alpha (TNF-α) and gamma interferon (IFN-γ) in...
Rogerson, Stephen J., Mkundika, Patrick, Kanjala, Maxwell K.
We compared peripheral and placental blood films (made by different techniques) with placental histology for diagnosis of Plasmodium falciparum malaria in pregnancy. Samples from 464 women were...
Elliott, Salenna R., Duffy, Michael F., Byrne, Timothy J., Beeson, James G., Mann, Emily J., Wilson, Danny W., ...
Malaria in pregnancy is associated with placental accumulation of Plasmodium falciparum-infected erythrocytes (IE) that adhere to chondroitin sulfate A (CSA). Adhesion is mediated by P. falciparum...
Alker, Alisa P., Mwapasa, Victor, Purfield, Anne, Rogerson, Stephen J., Molyneux, Malcolm E., Kamwendo, Deborah D., ...
We conducted a prevalence study of mutations in Plasmodium falciparum that are associated with antifolate resistance in Blantyre, Malawi. The dihydrofolate reductase 164-Leu mutation, which confers...
Elliott, Salenna R., Brennan, Amy K., Beeson, James G., Tadesse, Eyob, Molyneux, Malcolm E., Brown, Graham V., ...
Antibodies targeting variant antigens on the surfaces of chondroitin sulfate A (CSA)-binding malaria-infected erythrocytes have been linked to protection against the complications of malaria in...
Malaria during pregnancy and foetal haematological status in Blantyre, Malawi
Abrams, Elizabeth T, Kwiek, Jesse J, Mwapasa, Victor, Kamwendo, Deborah D, Tadesse, Eyob, Lema, Valentino M, ...
Maternal–Fetal Microtransfusions and HIV-1 Mother-to-Child Transmission in Malawi
Kwiek, Jesse J, Mwapasa, Victor, Milner, Danny A, Alker, Alisa P, Miller, William C, Tadesse, Eyob, ...
Placental microtransfusions as measured by placental alkaline phosphatase levels in cord blood are a risk factor for mother-to-child transmission during vaginal deliveries.
Frankland, Sarah, Adisa, Akinola, Horrocks, Paul, Taraschi, Theodore F., Schneider, Timothy, Elliott, Salenna R., ...
The particular virulence of the human malaria parasite Plasmodium falciparum derives from export of parasite-encoded proteins to the surface of the mature erythrocytes in which it resides. The...
Transcribed var Genes Associated with Placental Malaria in Malawian Women†
Duffy, Michael F., Caragounis, Aphrodite, Noviyanti, Rintis, Kyriacou, Helen M., Choong, Ee Ken, Boysen, Katja, ...
Determining the diversity of PfEMP1 sequences expressed by Plasmodium falciparum-infected erythrocytes isolated from placentas is important for attempts to develop a pregnancy-specific malaria...
Reeder, John C., Cowman, Alan F., Davern, Kathleen M., Beeson, James G., Thompson, Jennifer K., Rogerson, Stephen J., ...
Chondroitin sulfate A (CSA) is an important receptor for the sequestration of Plasmodium falciparum in the placenta, but the parasite ligand involved in adhesion has not previously been identified....
MacDonald, Susan M., Bhisutthibhan, Jamaree, Shapiro, Theresa A., Rogerson, Stephen J., Taylor, Terrie E., Tembo, Madalitso, ...
The Plasmodium falciparum translationally controlled tumor protein (TCTP) is a homolog of the mammalian histamine-releasing factor (HRF), which causes histamine release from human basophils and IL-8...
Plasmodium falciparum Rosette Formation Is Uncommon in Isolates from Pregnant Women
Rogerson, Stephen J., Beeson, James G., Mhango, Chisale G., Dzinjalamala, Fraction K., Molyneux, Malcolm E.
We examined the formation of Plasmodium falciparum erythrocyte rosettes using parasite isolates from placental or peripheral blood of pregnant Malawian women and from peripheral blood of children....
Beeson, James G., Chai, Wengang, Rogerson, Stephen J., Lawson, Alexander M., Brown, Graham V.
Adherence of parasite-infected erythrocytes (IEs) to the microvascular endothelium of various organs, a process known as sequestration, is a feature of Plasmodium falciparum malaria. This event is...
Mankhambo, Limangeni, Kanjala, Maxwell, Rudman, Sarah, Lema, Valentino M., Rogerson, Stephen J.
During pregnancy, Plasmodium falciparum infection of the placenta frequently occurs in the absence of parasites in peripheral blood. We investigated the abilities of the OptiMAL rapid...
Beeson, James G., Amin, Nishal, Kanjala, Maxwell, Rogerson, Stephen J.
A feature of malaria in pregnancy is accumulation of P. falciparum-infected erythrocytes (IEs) in the placenta, which is associated with adverse outcomes for mothers and infants. Infection appears to...
Rogerson, Stephen J., Brown, Heidi C., Pollina, Elena, Abrams, Elizabeth T., Tadesse, Eyob, Lema, Valentino M., ...
Malaria in pregnancy predisposes to maternal anemia and low birth weight (LBW). We examined the possible roles of the cytokines tumor necrosis factor alpha (TNF-α) and gamma interferon (IFN-γ) in...
Rogerson, Stephen J., Mkundika, Patrick, Kanjala, Maxwell K.
We compared peripheral and placental blood films (made by different techniques) with placental histology for diagnosis of Plasmodium falciparum malaria in pregnancy. Samples from 464 women were...
Elliott, Salenna R., Duffy, Michael F., Byrne, Timothy J., Beeson, James G., Mann, Emily J., Wilson, Danny W., ...
Malaria in pregnancy is associated with placental accumulation of Plasmodium falciparum-infected erythrocytes (IE) that adhere to chondroitin sulfate A (CSA). Adhesion is mediated by P. falciparum...
Alker, Alisa P., Mwapasa, Victor, Purfield, Anne, Rogerson, Stephen J., Molyneux, Malcolm E., Kamwendo, Deborah D., ...
We conducted a prevalence study of mutations in Plasmodium falciparum that are associated with antifolate resistance in Blantyre, Malawi. The dihydrofolate reductase 164-Leu mutation, which confers...
Elliott, Salenna R., Brennan, Amy K., Beeson, James G., Tadesse, Eyob, Molyneux, Malcolm E., Brown, Graham V., ...
Antibodies targeting variant antigens on the surfaces of chondroitin sulfate A (CSA)-binding malaria-infected erythrocytes have been linked to protection against the complications of malaria in...
Malaria during pregnancy and foetal haematological status in Blantyre, Malawi
Abrams, Elizabeth T, Kwiek, Jesse J, Mwapasa, Victor, Kamwendo, Deborah D, Tadesse, Eyob, Lema, Valentino M, ...
Maternal–Fetal Microtransfusions and HIV-1 Mother-to-Child Transmission in Malawi
Kwiek, Jesse J, Mwapasa, Victor, Milner, Danny A, Alker, Alisa P, Miller, William C, Tadesse, Eyob, ...
Placental microtransfusions as measured by placental alkaline phosphatase levels in cord blood are a risk factor for mother-to-child transmission during vaginal deliveries.
Frankland, Sarah, Adisa, Akinola, Horrocks, Paul, Taraschi, Theodore F., Schneider, Timothy, Elliott, Salenna R., ...
The particular virulence of the human malaria parasite Plasmodium falciparum derives from export of parasite-encoded proteins to the surface of the mature erythrocytes in which it resides. The...
Transcribed var Genes Associated with Placental Malaria in Malawian Women†
Duffy, Michael F., Caragounis, Aphrodite, Noviyanti, Rintis, Kyriacou, Helen M., Choong, Ee Ken, Boysen, Katja, ...
Determining the diversity of PfEMP1 sequences expressed by Plasmodium falciparum-infected erythrocytes isolated from placentas is important for attempts to develop a pregnancy-specific malaria...
Dobaño, Carlota, Rogerson, Stephen J., Taylor, Terrie E., McBride, Jana S., Molyneux, Malcolm E.
Sequestration of Plasmodium falciparum-infected erythrocytes is a pathological feature of fatal cerebral malaria. P. falciparum is genetically diverse among, and often within, patients. Preferential...
CCR5 Haplotypes and Mother-to-Child HIV Transmission in Malawi
Pedersen, Bonnie R., Kamwendo, Deborah, Blood, Melinda, Mwapasa, Victor, Molyneux, Malcolm, North, Kari, ...
Disruption of Var2csa Gene Impairs Placental Malaria Associated Adhesion Phenotype
Viebig, Nicola K., Levin, Emily, Dechavanne, Sébastien, Rogerson, Stephen J., Gysin, Jürg, Smith, Joseph D., ...
Infection with Plasmodium falciparum during pregnancy is one of the major causes of malaria related morbidity and mortality in newborn and mothers. The complications of pregnancy-associated malaria...
Elliott, Salenna R., Spurck, Timothy P., Dodin, Joelle M., Maier, Alexander G., Voss, Till S., Yosaatmadja, Francisca, ...
Red blood cells infected with Plasmodium falciparum (iRBCs) have been shown to modulate maturation of human monocyte-derived dendritic cells (DCs), interfering with their ability to activate T cells....
Kalilani, Linda, Mofolo, Innocent, Chaponda, Marjorie, Rogerson, Stephen J., Alker, Alisa P., Kwiek, Jesse J., ...
Frankland, Sarah, Elliott, Salenna R., Yosaatmadja, Francisca, Beeson, James G., Rogerson, Stephen J., Adisa, Akinola, ...
The virulence of the malaria parasite Plasmodium falciparum is related to its ability to express a family of adhesive proteins known as P. falciparum erythrocyte membrane protein 1 (PfEMP1) at the...
Differential var gene expression in the organs of patients dying of falciparum malaria
Montgomery, Jacqui, Mphande, Fingani A, Berriman, Matthew, Pain, Arnab, Rogerson, Stephen J, Taylor, Terrie E, ...
Sequestration of parasitized erythrocytes in the microcirculation of tissues is thought to be important in the pathogenesis of severe falciparum malaria. A major variant surface antigen,...
Yosaatmadja, Francisca, Andrews, Katherine T, Duffy, Michael F, Brown, Graham V, Beeson, James G, Rogerson, Stephen J
Dembo, Edson G., Mwapasa, Victor, Montgomery, Jacqui, Craig, Alister G., Porter, Kimberly A., Meshnick, Steven R., ...
Human immunodeficiency virus (HIV) increases susceptibility to Plasmodium falciparum infection, and this has most clearly been demonstrated in pregnant women. Variant surface antigens on the surfaces...
Severe Vivax Malaria: Newly Recognised or Rediscovered?
Rogerson, Stephen J, Carter, Richard
Stephen Rogerson and Richard Carter discuss two new studies that challenge current dogma by suggesting that vivax malaria can cause severe disease.