Arsenic-Based Antineoplastic Drugs and Their Mechanisms of Action (2008)
Arsenic-based compounds have become accepted agents for cancer therapy providing high rates of remission of some cancers such as acute promyelocytic leukemia (APL). The mechanisms by which...
Dong, Lan-feng, Low, Pauline, Dyason, Jeffrey Clifford, Wang, Xiufang, Prochazka, L, Witting, PK, ...
α-Tocopheryl succinate (α-TOS) is a selective inducer of apoptosis in cancer cells, which involves the accumulation of reactive oxygen species (ROS). The molecular target of α-TOS has not been...
Dong, Lan-feng, Low, Pauline, Dyason, Jeffrey Clifford, Wang, Xiufang, Prochazka, L, Witting, PK, ...
α-Tocopheryl succinate (α-TOS) is a selective inducer of apoptosis in cancer cells, which involves the accumulation of reactive oxygen species (ROS). The molecular target of α-TOS has not been...
Dong, Lan-feng, Low, Pauline, Dyason, Jeffrey Clifford, Wang, Xiufang, Prochazka, L, Witting, PK, ...
α-Tocopheryl succinate (α-TOS) is a selective inducer of apoptosis in cancer cells, which involves the accumulation of reactive oxygen species (ROS). The molecular target of α-TOS has not been...
Powell, Katie, Laakso, Liisa, Low, Pauline, Ralph, Stephen John
Objective: The aim of this investigation was to compare the cell proliferative effects of a range of doses of low level laser therapy (LLLT) at wavelengths of 780, 830 and 904 nm on human breast and...
Powell, Katie, Laakso, Liisa, Low, Pauline, Ralph, Stephen John
Objective: The aim of this investigation was to compare the cell proliferative effects of a range of doses of low level laser therapy (LLLT) at wavelengths of 780, 830 and 904 nm on human breast and...
Arsenic-Based Antineoplastic Drugs and Their Mechanisms of Action (2008)
Arsenic-based compounds have become accepted agents for cancer therapy providing high rates of remission of some cancers such as acute promyelocytic leukemia (APL). The mechanisms by which...
Wang, Xiufang, Birringer, Marc, Dong, Lan-feng, Veprek, Pavel, Low, Pauline, Cowie, Emma Angela, ...
Overexpression of erbB2 is associated with resistance to apoptosis. We explored whether high level of erbB2 expression by cancer cells allows their targeting using an erbB2-binding peptide (LTVSPWY)...
Neuzil, Jiri, Tomasetti, Marco, Zhao, Yan, Dong, Lan-feng, Birringer, Marc, Wang, Xiufang, ...
The search for a selective and efficient anticancer agent for treating all neoplastic disease has yet to deliver a universally suitable compound(s). The majority of established anticancer drugs...
Neuzil, Jiri, Dyason, Jeffrey Clifford, Freeman, Ruth, Dong, Lan-feng, Prochazka, Lubomir, Wang, Xiufang, ...
Recently mitochondria in cancer cells have emerged as the Achilles heel for tumour destruction. Anti-cancer agents specifically targeting cancer cell mitochondria are referred to as 'mitocans'. These...
Currently, cancer vaccine therapy for melanoma has a 2-fold focus. On the one hand, advances have been aimed at improving the effectiveness of melanoma vaccines based on a greater understanding of...
Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)
Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...
Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...
Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...
Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...
Dong, Lan-feng, Cowie, Emma Angela, Eliasson, Johanna Maria, Wang, Xiufang, Gold, Mikhal, Medunic, Yasmine, ...
''Mitocans'' from the vitamin E group of selective anticancer drugs, A-tocopheryl succinate (A-TOS) and its ether analogue A-TEA, triggered apoptosis in proliferating but not arrested endothelial...
Wang, Xiufang, Birringer, Marc, Dong, Lan-feng, Veprek, Pavel, Low, Pauline, Cowie, Emma Angela, ...
Overexpression of erbB2 is associated with resistance to apoptosis. We explored whether high level of erbB2 expression by cancer cells allows their targeting using an erbB2-binding peptide (LTVSPWY)...
Neuzil, Jiri, Tomasetti, Marco, Zhao, Yan, Dong, Lan-feng, Birringer, Marc, Wang, Xiufang, ...
The search for a selective and efficient anticancer agent for treating all neoplastic disease has yet to deliver a universally suitable compound(s). The majority of established anticancer drugs...
Neuzil, Jiri, Dyason, Jeffrey Clifford, Freeman, Ruth, Dong, Lan-feng, Prochazka, Lubomir, Wang, Xiufang, ...
Recently mitochondria in cancer cells have emerged as the Achilles heel for tumour destruction. Anti-cancer agents specifically targeting cancer cell mitochondria are referred to as 'mitocans'. These...
Currently, cancer vaccine therapy for melanoma has a 2-fold focus. On the one hand, advances have been aimed at improving the effectiveness of melanoma vaccines based on a greater understanding of...
Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)
Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...
Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...
Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...
Dong, Lan-feng, Cowie, Emma Angela, Eliasson, Johanna Maria, Wang, Xiufang, Gold, Mikhal, Medunic, Yasmine, ...
Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)
Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...
Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...
Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...
Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...
Dong, Lan-feng, Cowie, Emma Angela, Eliasson, Johanna Maria, Wang, Xiufang, Gold, Mikhal, Medunic, Yasmine, ...
''Mitocans'' from the vitamin E group of selective anticancer drugs, A-tocopheryl succinate (A-TOS) and its ether analogue A-TEA, triggered apoptosis in proliferating but not arrested endothelial...
Wang, Xiufang, Birringer, Marc, Dong, Lan-feng, Veprek, Pavel, Low, Pauline, Cowie, Emma Angela, ...
Overexpression of erbB2 is associated with resistance to apoptosis. We explored whether high level of erbB2 expression by cancer cells allows their targeting using an erbB2-binding peptide (LTVSPWY)...
Neuzil, Jiri, Tomasetti, Marco, Zhao, Yan, Dong, Lan-feng, Birringer, Marc, Wang, Xiufang, ...
The search for a selective and efficient anticancer agent for treating all neoplastic disease has yet to deliver a universally suitable compound(s). The majority of established anticancer drugs...
Neuzil, Jiri, Dyason, Jeffrey Clifford, Freeman, Ruth, Dong, Lan-feng, Prochazka, Lubomir, Wang, Xiufang, ...
Recently mitochondria in cancer cells have emerged as the Achilles heel for tumour destruction. Anti-cancer agents specifically targeting cancer cell mitochondria are referred to as 'mitocans'. These...
Currently, cancer vaccine therapy for melanoma has a 2-fold focus. On the one hand, advances have been aimed at improving the effectiveness of melanoma vaccines based on a greater understanding of...
Tumour-initiating cells vs. cancer 'stem' cells and CD133: What's in the name? (2007)
Neuzil, Jiri, Stantic, Marina, Zobalova, Renata, Chladova, Jaromira, Wang, Xiufang, Prochazka, Lubomir, ...
Recent evidence suggests that a subset of cells within a tumour have 'stem-like' characteristics. These tumour-initiating cells, distinct from non-malignant stem cells, show low proliferative rates,...
Neuzil, Jiri, Dong, Lan-feng, Ramanathapuram, Lalitha, Hahn, Tobias, Chladova, Miroslava, Wang, Xiufang, ...
Mitochondria have recently emerged as new and promising targets for cancer prevention and therapy. One of the reasons for this is that mitochondria are instrumental to many types of cell death and...
Dong, Lan-feng, Cowie, Emma Angela, Eliasson, Johanna Maria, Wang, Xiufang, Gold, Mikhal, Medunic, Yasmine, ...
''Mitocans'' from the vitamin E group of selective anticancer drugs, A-tocopheryl succinate (A-TOS) and its ether analogue A-TEA, triggered apoptosis in proliferating but not arrested endothelial...
Neuzil, Jiri, Wang, Xiufang, Dong, Lan-feng, Low, Pauline, Ralph, Stephen John
Mitochondria have emerged recently as effective targets for novel anti-cancer drugs referred to as 'mitocans'. We propose that the molecular mechanism of induction of apoptosis by mitocans, as...
Neuzil, Jiri, Wang, Xiufang, Dong, Lan-feng, Low, Pauline, Ralph, Stephen John
Mitochondria have emerged recently as effective targets for novel anti-cancer drugs referred to as 'mitocans'. We propose that the molecular mechanism of induction of apoptosis by mitocans, as...
Neuzil, Jiri, Wang, Xiufang, Dong, Lan-feng, Low, Pauline, Ralph, Stephen John
Mitochondria have emerged recently as effective targets for novel anti-cancer drugs referred to as 'mitocans'. We propose that the molecular mechanism of induction of apoptosis by mitocans, as...
Ralph, Stephen John, Low, Pauline, Dong, Lan-feng, Lawen, Alfons, Neuzil, Jiri
Mitochondria are proving to be worthy targets for activating specific killing of cancer cells in tumors and a diverse range of mitochondrial targeted drugs are currently in clinical trial to...
Ralph, Stephen John, Low, Pauline, Dong, Lan-feng, Lawen, Alfons, Neuzil, Jiri
Mitochondria are proving to be worthy targets for activating specific killing of cancer cells in tumors and a diverse range of mitochondrial targeted drugs are currently in clinical trial to...
Neuzil, Jiri, Wang, Xiufang, Dong, Lan-feng, Low, Pauline, Ralph, Stephen John
Mitochondria have emerged recently as effective targets for novel anti-cancer drugs referred to as 'mitocans'. We propose that the molecular mechanism of induction of apoptosis by mitocans, as...
Ralph, Stephen John, Low, Pauline, Dong, Lan-feng, Lawen, Alfons, Neuzil, Jiri
Mitochondria are proving to be worthy targets for activating specific killing of cancer cells in tumors and a diverse range of mitochondrial targeted drugs are currently in clinical trial to...
Ghazawi, I., Cutler, S., Low, Pauline, Mellick, Albert, Ralph, Stephen John
Luciferase reporter constructs are widely used for analysis of gene regulation when characterizing promoter and enhancer elements. We report that the recently developed codon-modified Renilla...
Ghazawi, I., Cutler, S., Low, Pauline, Mellick, Albert, Ralph, Stephen John
Luciferase reporter constructs are widely used for analysis of gene regulation when characterizing promoter and enhancer elements. We report that the recently developed codon-modified Renilla...
Ghazawi, I., Cutler, S., Low, Pauline, Mellick, Albert, Ralph, Stephen John
Luciferase reporter constructs are widely used for analysis of gene regulation when characterizing promoter and enhancer elements. We report that the recently developed codon-modified Renilla...
Dezfouli, Shala, Hatzinisiriou, Irene, Ralph, Stephen John
Sequentially treating human melanoma cell lines by priming with interferon-gamma before adding interferon-beta was previously found to be the most efficient protocol for producing concurrently...
Dezfouli, Shala, Hatzinisiriou, Irene, Ralph, Stephen John
Sequentially treating human melanoma cell lines by priming with interferon-gamma before adding interferon-beta was previously found to be the most efficient protocol for producing concurrently...
Dezfouli, Shala, Hatzinisiriou, Irene, Ralph, Stephen John
Sequentially treating human melanoma cell lines by priming with interferon-gamma before adding interferon-beta was previously found to be the most efficient protocol for producing concurrently...
Dezfouli, Shala, Hatzinisiriou, Irene, Ralph, Stephen John
Sequentially treating human melanoma cell lines by priming with interferon-gamma before adding interferon-beta was previously found to be the most efficient protocol for producing concurrently...
Wong, Lee H., Sim, Helena, Chatterjee-Kishore, Moitreyee, Hatzinisiriou, Irene, Devenish, Rodney J., Stark, George, ...
The transcription factor STAT1 plays a pivotal role in signal transduction of type I and II interferons (IFNs). STAT1 activation leads to changes in expression of key regulatory genes encoding...
Wong, Lee H., Sim, Helena, Chatterjee-Kishore, Moitreyee, Hatzinisiriou, Irene, Devenish, Rodney J., Stark, George, ...
The transcription factor STAT1 plays a pivotal role in signal transduction of type I and II interferons (IFNs). STAT1 activation leads to changes in expression of key regulatory genes encoding...
Wong, Lee H., Sim, Helena, Chatterjee-Kishore, Moitreyee, Hatzinisiriou, Irene, Devenish, Rodney J., Stark, George, ...
The transcription factor STAT1 plays a pivotal role in signal transduction of type I and II interferons (IFNs). STAT1 activation leads to changes in expression of key regulatory genes encoding...
Arsenic-Based Antineoplastic Drugs and Their Mechanisms of Action
Arsenic-based compounds have become accepted agents for cancer therapy providing high rates of remission of some cancers such as acute promyelocytic leukemia (APL). The mechanisms by which...