Disruption of the Non-Canonical WNT Pathway in Lung Squamous Cell Carcinoma (2008)
Raj Chari, Andy Lam, Raymond T. Ng, John Yee, John English, ...
Disruptions of beta-catenin and the canonical Wnt pathway are well documented in cancer. However, little is known of the non-canonical branch of the Wnt pathway. In this study, we investigate the...
Disruption of the Non-Canonical WNT Pathway in Lung Squamous Cell Carcinoma (2008)
Raj Chari, Andy Lam, Raymond T. Ng, John Yee, John English, ...
Disruptions of beta-catenin and the canonical Wnt pathway are well documented in cancer. However, little is known of the non-canonical branch of the Wnt pathway. In this study, we investigate the...
Effect of active smoking on the human bronchial epithelium transcriptome (2007)
Chari, Raj, Lonergan, Kim M, Ng, Raymond T, MacAulay, Calum, Lam, Wan L, Lam, Stephen
Abstract Background Lung cancer is the most common cause of cancer-related deaths. Tobacco smoke exposure is the strongest aetiological factor associated with lung cancer. In this study, using serial...
Bmc Genomics, Raj Chari, Kim M Lonergan, Raymond T Ng, Calum Macaulay, Wan L Lam, ...
Research article Effect of active smoking on the human bronchial epithelium transcriptome
Malhotra, Samir, Lam, Stephen, Man, SF Paul, Gan, Wen Q, Sin, Don D
Abstract Background Reduced forced expiratory volume in one second (FEV 1 ) has been linked to non small cell lung cancer (NSCLC). However, it is unclear whether all or only certain histological...
Tichelaar, Jay W, Zhang, Yu, LeRiche, Jean C, Biddinger, Paul W, Lam, Stephen, Anderson, Marshall W
Abstract Background The development of non-small cell lung carcinoma proceeds through a series of well-defined pathological steps before the appearance of invasive lung carcinoma. The molecular...
Involvement of multiple developmental genes on chromosome 1p in lung tumorigenesis (2005)
Garnis, Cathie, Campbell, Jennifer, Davies, Jonathan J., MacAulay, Calum, Lam, Stephen, Lam, Wan L.
Lung cancer is the leading cause of cancer death in North America. Despite advances in lung cancer treatment, the overall 5 year survival rate for those diagnosed with the disease is bleak presumably...
Methodology to minimize cost and time for new data warehouse implementations (2004)
Bibliography : p. 112-116
Isometric data sequences and data-modulation schemes in fading channels (2004)
Plataniotis, Konstantinos, Lam, Stephen, Pasupathy, Subbarayan
Methodology to minimize cost and time for new data warehouse implementations [microform] / (2004)
"MQ-97597."
Methodology to minimize cost and time for new data warehouse implementations (2004)
Bibliography : p. 112-116
Involvement of multiple developmental genes on chromosome 1p in lung tumorigenesis (2004)
Garnis, Cathie, Campbell, Jennifer, Davies, Jonathan J., MacAulay, Calum, Lam, Stephen, Lam, Wan L.
Lung cancer is the leading cause of cancer death in the North America. Despite advances in lung cancer treatment, the overall 5 year survival rate for those diagnosed with the disease is bleak...
Involvement of multiple developmental genes on chromosome 1p in lung tumorigenesis (2004)
Garnis, Cathie, Campbell, Jennifer, Davies, Jonathan J., MacAulay, Calum, Lam, Stephen, Lam, Wan L.
Lung cancer is the leading cause of cancer death in the North America. Despite advances in lung cancer treatment, the overall 5 year survival rate for those diagnosed with the disease is bleak...
A Randomized Phase IIb Trial of Anethole Dithiolethione in Smokers with Bronchial Dysplasia (2002)
Lam, Stephen, MacAulay, Calum, Le Riche, Jean C., Dyachkova, Yulia, Coldman, Andy, Guillaud, Martial, ...
Background: Results from preclinical studies have suggested that the organosulfur compound anethole dithiolethione (ADT) may be an effective chemopreventive agent for lung cancer. We conducted a...
A study of audit fee determinants and premium in Singapore / (2001)
Li, Wenqi., Qiu, Xihua., Lam, Stephen.
Thesis (M.B.A.)--Nanyang Technological University, Nanyang Business School, 2001.
Gazdar, Adi F., Zöchbauer-Möller, Sabine, Virmani, Arvind, Kurie, Jonathan, Minna, John D., Lam, Stephen
Lam, Stephen, Palcic, Branko, Venmans, Ben J., Smit, Egbert F., Postmus, Pieter E., Sutedja, Thomas G., ...
Sex-Related Differences in Bronchial Epithelial Changes Associated With Tobacco Smoking (1999)
Lam, Stephen, LeRiche, Jean C., Zheng, Yvonne, Coldman, Andrew, MacAulay, Calum, Hawk, Ernest, ...
BACKGROUND: Lung cancer is the most common cause of cancer death in North American women. Because smoking-related changes in the bronchial epithelium and in lung function have not been studied in...
A New Data Acquisition System for the AMRL Low Speed Wind Tunnel (1998)
Holland, Owen, Lam, Stephen, Link, Yoel
The data acquisition system in the Low Speed Wind Tunnel at the Aeronautical and Maritime Research Laboratory was recently upgraded. The MicroVAX II host computer was replaced by a Digital...
DSTO operates a low speed wind tunnel within the Air Vehicles Division of the Platforms Sciences Laboratory. Airspeeds up to approximately 100 m/s can be produced in the empty test section which is...
Document Understanding: Research Directions (1992)
Sargur Srihari, Sargur Srihari, Stephen Lam, Stephen Lam, Venu Govindaraju, Venu Govindaraju, ...
A document image is a visual representation of a printed page such as a journal article page, a facsimile cover page, a technical document, an o#ce letter, etc. Document understanding as a research...
Document Understanding: Research Directions (1992)
Sargur Srihari, Sargur Srihari, Stephen Lam, Stephen Lam, Venu Govindaraju, Venu Govindaraju, ...
A document image is a visual representation of a printed page such as a journal article page, a facsimile cover page, a technical document, an office letter, etc. Document understanding as a research...
Zhang, Yan, Lamm, Randy, Pillonel, Christian, Lam, Stephen, Xu, Jin-Rong
Neurospora crassa osmosensitive (os) mutants are sensitive to high osmolarity and therefore are unable to grow on medium containing 4% NaCl. We found that os-2 and os-5 mutants were resistant to the...
Increased staining for phospho-Akt, p65/RELA and cIAP-2 in pre-neoplastic human bronchial biopsies
Tichelaar, Jay W, Zhang, Yu, LeRiche, Jean C, Biddinger, Paul W, Lam, Stephen, Anderson, Marshall W
The relationship between stage 1 and 2 non-small cell lung cancer and lung function in men and women
Malhotra, Samir, Lam, Stephen, Man, SF Paul, Gan, Wen Q, Sin, Don D
Genetic Mapping of Is200 Copies in SALMONELLA TYPHIMURIM Strain Lt2
The wild-type Salmonella typhimurium strain LT2 contains six copies of the insertion sequence element IS200 which is unique to Salmonella. We have determined the chromosomal locations of all six...
The Distribution of Crossovers along Unreplicated Lambda Bacteriophage Chromosomes
Stahl, Franklin W., McMilin, Kenneth D., Stahl, Mary M., Crasemann, Jean M., Lam, Stephen
The distribution of crossovers along unreplicated chromosomes of bacteriophage lambda has been examined by determining the density distributions and genotypes of particles in the progenies of crosses...
Zhang, Yan, Lamm, Randy, Pillonel, Christian, Lam, Stephen, Xu, Jin-Rong
Neurospora crassa osmosensitive (os) mutants are sensitive to high osmolarity and therefore are unable to grow on medium containing 4% NaCl. We found that os-2 and os-5 mutants were resistant to the...
Genetic Mapping of Is200 Copies in SALMONELLA TYPHIMURIM Strain Lt2
The wild-type Salmonella typhimurium strain LT2 contains six copies of the insertion sequence element IS200 which is unique to Salmonella. We have determined the chromosomal locations of all six...
The Distribution of Crossovers along Unreplicated Lambda Bacteriophage Chromosomes
Stahl, Franklin W., McMilin, Kenneth D., Stahl, Mary M., Crasemann, Jean M., Lam, Stephen
The distribution of crossovers along unreplicated chromosomes of bacteriophage lambda has been examined by determining the density distributions and genotypes of particles in the progenies of crosses...
Increased staining for phospho-Akt, p65/RELA and cIAP-2 in pre-neoplastic human bronchial biopsies
Tichelaar, Jay W, Zhang, Yu, LeRiche, Jean C, Biddinger, Paul W, Lam, Stephen, Anderson, Marshall W
The relationship between stage 1 and 2 non-small cell lung cancer and lung function in men and women
Malhotra, Samir, Lam, Stephen, Man, SF Paul, Gan, Wen Q, Sin, Don D
Effect of active smoking on the human bronchial epithelium transcriptome
Chari, Raj, Lonergan, Kim M, Ng, Raymond T, MacAulay, Calum, Lam, Wan L, Lam, Stephen
Chromosomal Aneusomy in Bronchial High-Grade Lesions Is Associated with Invasive Lung Cancer
Jonsson, Steinn, Varella-Garcia, Marileila, Miller, York E., Wolf, Holly J., Byers, Tim, Braudrick, Sarah, ...
Rationale: The development of lung cancer (LC) is accompanied by field changes in the airway mucosa that may have prognostic importance.
Progression of Airway Dysplasia and C-Reactive Protein in Smokers at High Risk of Lung Cancer
Sin, Don D., Man, S. F. Paul, McWilliams, Annette, Lam, Stephen
Rationale: Chronic inflammation has been implicated in the development of airway dysplasia and lung cancer. It is unclear whether circulating biomarkers of inflammation could be used to predict...
Airway Wall Thickness Assessed Using Computed Tomography and Optical Coherence Tomography
Coxson, Harvey O., Quiney, Brendan, Sin, Don D., Xing, Li, McWilliams, Annette M., Mayo, John R., ...
Rationale: Computed tomography (CT) has been shown to reliably measure the airway wall dimensions of medium to large airways. Optical coherence tomography (OCT) is a promising new micron-scale...
Recurrent Genomic Gains in Preinvasive Lesions as a Biomarker of Risk for Lung Cancer
Massion, Pierre P., Zou, Yong, Uner, Hasmet, Kiatsimkul, Porntip, Wolf, Holly J., Baron, Anna E., ...
Lung carcinoma development is accompanied by field changes that may have diagnostic significance. We have previously shown the importance of chromosomal aneusomy in lung cancer progression. Here, we...