Steven E. Ealick

Structure of variant 2 scorpion toxin from Centruroides sculpturatus Ewing (2002)

Cook, William J., Zell, Alan, Watt, Dean D., Ealick, Steven E.

Centruroides sculpturatus Ewing variant 2 toxin (CsE-v2) is a neurotoxin isolated from the venom of a scorpion native to the Arizona desert. The structure of CsE-v2 was solved in two different...

The crystal structure and mechanism of orotidine 5′-monophosphate decarboxylase

Appleby, Todd C., Kinsland, Cynthia, Begley, Tadhg P., Ealick, Steven E.

The crystal structure of Bacillus subtilis orotidine 5′-monophosphate (OMP) decarboxylase with bound uridine 5′-monophosphate has been determined by multiple wavelength anomalous diffraction...

Three-dimensional diffuse x-ray scattering from crystals of Staphylococcal nuclease

Wall, Michael E., Ealick, Steven E., Gruner, Sol M.

We have developed methods for obtaining and characterizing three-dimensional maps of the reciprocal-space distribution of diffuse x-ray scattering from protein crystals, and have used the methods to...

The Shake-and-Bake structure determination of triclinic lysozyme

Deacon, Ashley M., Weeks, Charles M., Miller, Russ, Ealick, Steven E.

The crystal structure of triclinic lysozyme, comprised of 1,001 non-H protein atoms and ≈200 bound water molecules, has been determined ab initio (using native data alone) by the...

Structural analyses reveal two distinct families of nucleoside phosphorylases.

Pugmire, Matthew J, Ealick, Steven E

The reversible phosphorolysis of purine and pyrimidine nucleosides is an important biochemical reaction in the salvage pathway, which provides an alternative to the de novo purine and pyrimidine...

The crystal structure and mechanism of orotidine 5′-monophosphate decarboxylase

Appleby, Todd C., Kinsland, Cynthia, Begley, Tadhg P., Ealick, Steven E.

The crystal structure of Bacillus subtilis orotidine 5′-monophosphate (OMP) decarboxylase with bound uridine 5′-monophosphate has been determined by multiple wavelength anomalous diffraction...

Three-dimensional diffuse x-ray scattering from crystals of Staphylococcal nuclease

Wall, Michael E., Ealick, Steven E., Gruner, Sol M.

We have developed methods for obtaining and characterizing three-dimensional maps of the reciprocal-space distribution of diffuse x-ray scattering from protein crystals, and have used the methods to...

The Shake-and-Bake structure determination of triclinic lysozyme

Deacon, Ashley M., Weeks, Charles M., Miller, Russ, Ealick, Steven E.

The crystal structure of triclinic lysozyme, comprised of 1,001 non-H protein atoms and ≈200 bound water molecules, has been determined ab initio (using native data alone) by the...

Structural analyses reveal two distinct families of nucleoside phosphorylases.

Pugmire, Matthew J, Ealick, Steven E

The reversible phosphorolysis of purine and pyrimidine nucleosides is an important biochemical reaction in the salvage pathway, which provides an alternative to the de novo purine and pyrimidine...

Structure of variant 2 scorpion toxin from Centruroides sculpturatus Ewing

Cook, William J., Zell, Alan, Watt, Dean D., Ealick, Steven E.

Centruroides sculpturatus Ewing variant 2 toxin (CsE-v2) is a neurotoxin isolated from the venom of a scorpion native to the Arizona desert. The structure of CsE-v2 was solved in two different...

Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii

Soriano, Erika V., McCloskey, Diane E., Kinsland, Cynthia, Pegg, Anthony E., Ealick, Steven E.

The crystal structures of two arginine decarboxylase mutant proteins provide insights into the mechanisms of pyruvoyl-group formation and the decarboxylation reaction.