One-pot controlled synthesis of biodegradable and biocompatible co-polymer micelles (2009)
Saeed, Aram Omer, Dey, Sabrina, Howdle, Steven M., Thurecht, Kristofer J., Alexander, Cameron
A facile route to biocompatible poly(lactic acid-co-glycolic acid)-co-poly(ethyleneglycolmethacrylate) (PLGA–PEGMA) block co-polymers is described utilising a combination of ring-opening...
Lagonigro, Laura, Peacock, Anna C., Rohrmoser, Stefan, Hasell, Tom, Howdle, Steven M., Sazio, Pier J.A., ...
Silver nanoparticle impregnated polycarbonate strips have been investigated as substrates for metal-enhanced photoluminescence of a blue emitting dye molecule (coumarin 102). By considering...
Ultra-high pressure MOCVD: a supercritical route to compound semiconductor materials (2008)
Wilson, James William, Yang, Jixin, Hyde, Jason R., Smith, David C., Howdle, Steven M., Mallik, Kanad, ...
The deposition of thin films of materials on to and in to preformed, high aspect ratio, template materials, is of significant interest to the semiconductor community. Damascene processes are vital to...
Grignard, Bruno, Jérôme, Christine, Calberg, Cédric, Jérôme, Robert, Wang, Wenxin, Howdle, Steven M, ...
Controlled dispersion atom transfer radical polymerization (ATRP) of methyl methacrylate (MMA) was successfully carried out in supercritical carbon dioxide in the presence of aminated fluoropolymers....
Peacock, Anna.C., Amezcua-Correa, Adrian., Yang, Jixin, Sazio, Pier.J.A., Howdle, Steven.M.
Microstructured optical fibers "MOFs" represent a promising platform technology for fully integrated photonic-plasmonic devices. In this paper, we experimentally investigate the properties of two MOF...
Grignard, Bruno, Jérôme, Christine, Calberg, Cédric, Jérôme, Robert, Wang, Wenxing, Howdle, Steven M, ...
We report the successful synthesis of poly(methyl methacrylate) (PMMA) by atom transfer radical polymerization using a catalyst ligated to a polymeric ligand having a dual role, i.e., the...
Heyde, Mieke, Partridge, Kris A., Howdle, Steven M., Oreffo, Richard O.C., Garnett, Martin C., Shakesheff, Kevin M.
Polyamidoamine polymers (PAA) comprising methylene-bisacrylamide/dimethylethylene-diamine monomers were synthesized, complexed with DNA and incorporated into porous P(DL)LA scaffolds by using a...
Gene therapy used for tissue engineering applications (2007)
Heyde, Mieke, Partridge, Kris A., Oreffo, Richard O.C., Howdle, Steven M., Shakesheff, Kevin M., Garnett, Martin C.
This review highlights the advances at the interface between tissue engineering and gene therapy. There are a large number of reports on gene therapy in tissue engineering, and these cover a huge...
Microscopic spacial effect on the dispersion polymerization in scCO2 (2007)
Yang, Jixin, Wang, Wenxin, Sazio, Pier J.A., Howdle, Steven M.
We report for the first time the microscopic spacial effect on the dispersion polymerization of methyl methacrylate (MMA) in supercritical carbon dioxide (scCO2). A variety of different-sized...
Microscopic spacial effect on the dispersion polymerization in scCO2 (2007)
Yang, Jixin, Wang, Wenxin, Sazio, Pier J.A., Howdle, Steven M.
We report for the first time the microscopic spacial effect on the dispersion polymerization of methyl methacrylate (MMA) in supercritical carbon dioxide (scCO). A variety of different-sized...
Hasell, Tom, Thurecht, Kristofer J., Jones, Rhys D. W., Brown, Paul D., Howdle, Steven M.
We report the one pot synthesis of a silver–polymer nanocomposite in supercritical carbon dioxide (scCO2) whereby an organometallic silver complex is thermally decomposed in the presence of a...
Controlled dispersion polymerization in supercritical carbon dioxide by RAFT (2007)
Gregory, Andrew M., Thurecht, Kristofer J., Howdle, Steven M.
Supercritical CO2: an effective medium for the chemo-enzymatic synthesis of block copolymers (2007)
Villarroya, Silvia, Thurecht, Kristofer J., Heise, Andreas, Howdle, Steven M.
In this review, we describe the combination of enzymatic polymerisation and controlled free radical polymerisation in supercritical carbon dioxide. This combination facilitates the preparation of a...
“Living” Polymer Beads in Supercritical CO2 (2007)
Thurecht, Kristofer J., Gregory, Andrew M., Wang, Wenxin, Howdle, Steven M.
GECO-DOSY Post-Processing Analysis of Polymers (2007)
Thurecht, Kristofer J., Howdle, Steven M., Davis, Adrienne L., Hyde, Jason R.
Generalized correlation diffusion ordered spectroscopy (GECO-DOSY) has been employed to increase the resolution of a more traditional DOSY experiment. We have compared purely linear polycaprolactone...
Hasell, Tom, Thurecht, Kristofer J., Jones, Rhys D. W., Brown, Paul D., Howdle, Steven M.
We report the one pot synthesis of a silver–polymer nanocomposite in supercritical carbon dioxide (scCO2) whereby an organometallic silver complex is thermally decomposed in the presence of a...
Controlled dispersion polymerization in supercritical carbon dioxide by RAFT (2007)
Gregory, Andrew M., Thurecht, Kristofer J., Howdle, Steven M.
Supercritical CO2: an effective medium for the chemo-enzymatic synthesis of block copolymers (2007)
Villarroya, Silvia, Thurecht, Kristofer J., Heise, Andreas, Howdle, Steven M.
In this review, we describe the combination of enzymatic polymerisation and controlled free radical polymerisation in supercritical carbon dioxide. This combination facilitates the preparation of a...
“Living” Polymer Beads in Supercritical CO2 (2007)
Thurecht, Kristofer J., Gregory, Andrew M., Wang, Wenxin, Howdle, Steven M.
GECO-DOSY Post-Processing Analysis of Polymers (2007)
Thurecht, Kristofer J., Howdle, Steven M., Davis, Adrienne L., Hyde, Jason R.
Generalized correlation diffusion ordered spectroscopy (GECO-DOSY) has been employed to increase the resolution of a more traditional DOSY experiment. We have compared purely linear polycaprolactone...
Yang, Jixin, Amezcua-Correa, Adrian, Peacock, Anna C., Finlayson, Chris E., Baumberg, Jeremy J., Howdle, Steven M., ...
In this paper we report the fabrication of microstructured optical fibers (MOFs) metallic metamaterials using a bottom-up processing technique for surface enhanced Raman scattering (SERS)...
Mammalian cell survival and processing in supercritical CO(2) (2006)
Ginty, Patrick J., Howard, Daniel, Whitaker, Martin J., Barry, John J.A., Tighe, Patrick, ...
We demonstrate that mammalian cells can survive for 5 min within high-pressure CO(2)(.) Cell survival was investigated by exposing a range of mammalian cell types to supercritical CO(2) (scCO(2)) (35...
Mammalian cell survival and processing in supercritical CO2 (2006)
Ginty, Patrick J., Howard, Daniel, Whitaker, Martin J., Barry, John J.A., Tighe, Patrick, ...
We demonstrate that mammalian cells can survive for 5 min within high-pressure CO(2)(.) Cell survival was investigated by exposing a range of mammalian cell types to supercritical CO(2) (scCO(2)) (35...
Zhou, Jiaxiang, Wang, Wenxin, Thurecht, Kristofer J., Villarroya, Silvia, Howdle, Steven M.
We report the simultaneous dynamic kinetic resolution (DKR) of a secondary alcohol in combination with lipase-catalyzed ring-opening polymerization (ROP) of ε-caprolactone (ε-CL)....
Zhou, Jiaxiang, Villarroya, Silvia, Wang, Wenxin, Wyatt, Mark F., Duxbury, Christopher J., Thurecht, Kristofer J., ...
Enzymatic ring-opening polymerization (eROP) of ε-caprolactone (ε-CL) and atom-transfer radical polymerization (ATRP) of methyl methacrylate (MMA) were integrated into a one-step chemoenzymatic...
Thurecht, Kristofer J., Gregory, Andrew M., Villarroya, Silvia, Zhou, Jiaxiang, Heise, Andreas, Howdle, Steven M.
This report presents the first simultaneous, metal-free synthesis of block copolymers through combination of enzymatic ring-opening polymerisation of -caprolactone with RAFT-mediated controlled...
Thurecht, Kristofer J., Heise, Andreas, DeGeus, Matthijs, Villarroya, Silvia, Zhou, Jiaxiang, Wyatt, Mark F., ...
The kinetics of enzymatic ring-opening polymerization (eROP) of ε-caprolactone in supercritical carbon dioxide (scCO2) was investigated using a new, high-pressure sampling autoclave. The...
Enzymatic polymerizations in supercritical carbon dioxide (2006)
Villarroya, Silvia, Zhou, Jiaxiang, Thurecht, Kristofer J., Howdle, Steven M.
Synthesis of graft copolymers by the combination of ATRP and Enzymatic ROP in scC02 (2006)
Villarroya, Silvia, Zhou, Jiaxiang, Thurect, Kristofer J., Howdle, Steven M.
A simple strategy is reported for the synthesis of well-defined graft copolymers of poly(methyl methacrylate-co-2-hydroxyethyl methacrylate) P(MMA-co-HEMA) with poly(ε-caprolactone) (PCL) grafted...
Zhou, Jiaxiang, Wang, Wenxin, Thurecht, Kristofer J., Villarroya, Silvia, Howdle, Steven M.
We report the simultaneous dynamic kinetic resolution (DKR) of a secondary alcohol in combination with lipase-catalyzed ring-opening polymerization (ROP) of ε-caprolactone (ε-CL)....
Zhou, Jiaxiang, Villarroya, Silvia, Wang, Wenxin, Wyatt, Mark F., Duxbury, Christopher J., Thurecht, Kristofer J., ...
Enzymatic ring-opening polymerization (eROP) of ε-caprolactone (ε-CL) and atom-transfer radical polymerization (ATRP) of methyl methacrylate (MMA) were integrated into a one-step chemoenzymatic...
Thurecht, Kristofer J., Gregory, Andrew M., Villarroya, Silvia, Zhou, Jiaxiang, Heise, Andreas, Howdle, Steven M.
This report presents the first simultaneous, metal-free synthesis of block copolymers through combination of enzymatic ring-opening polymerisation of -caprolactone with RAFT-mediated controlled...
Thurecht, Kristofer J., Heise, Andreas, DeGeus, Matthijs, Villarroya, Silvia, Zhou, Jiaxiang, Wyatt, Mark F., ...
The kinetics of enzymatic ring-opening polymerization (eROP) of ε-caprolactone in supercritical carbon dioxide (scCO2) was investigated using a new, high-pressure sampling autoclave. The...
Enzymatic polymerizations in supercritical carbon dioxide (2006)
Villarroya, Silvia, Zhou, Jiaxiang, Thurecht, Kristofer J., Howdle, Steven M.
Synthesis of graft copolymers by the combination of ATRP and Enzymatic ROP in scC02 (2006)
Villarroya, Silvia, Zhou, Jiaxiang, Thurect, Kristofer J., Howdle, Steven M.
A simple strategy is reported for the synthesis of well-defined graft copolymers of poly(methyl methacrylate-co-2-hydroxyethyl methacrylate) P(MMA-co-HEMA) with poly(ε-caprolactone) (PCL) grafted...
Yang, Xuebin B., Whitaker, Martin J., Sebald, Walter, Clarke, Nicholas, Howdle, Steven M., Shakesheff, Kevin M., ...
The ability to deliver, over time, biologically active osteogenic growth factors by means of designed scaffolds to sites of tissue regeneration offers tremendous therapeutic opportunities in a...
Furno, Franck, Morley, Kelly S., Wong, Ben, Sharp, Barry L., Arnold, Polly L., Howdle, Steven M., ...
Objectives: Implantable devices are major risk factors for hospital-acquired infection. Biomaterials coated with silver oxide or silver alloy have all been used in attempts to reduce infection, in...
Furno, Franck, Morley, Kelly S., Wong, Ben, Sharp, Barry L., Arnold, Polly L., Howdle, Steven M., ...
Objectives: Implantable devices are major risk factors for hospital-acquired infection. Biomaterials coated with silver oxide or silver alloy have all been used in attempts to reduce infection, in...
Charge transfer complex inimer: A facile route to dendritic materials (2003)
Wang, Wenxin, Yan, Deyue, Bratton, Daniel, Howdle, Steven M, Wang, Qiang, Lecomte, Philippe
A versatile approach to the preparation of hyperbranched polymers, in which an inimer is used to assemble a charge transfer complex (CTC) with conventional vinyl monomers, is reported. A novel...
Yang, Xuebin, Tare, Rahul S., Partridge, Kris A., Roach, Helmtrud, Clarke, Nicholas M.P., Howdle, Steven M., ...
The process of bone growth, regeneration, and remodeling is mediated, in part, by the immediate cell-matrix environment. Osteoblast stimulating factor-1 (OSF-1), more commonly known as pleiotrophin...
Howard, Daniel, Partridge, Kris, Yang, Xuebin, Clarke, Nicholas M.P., Okubo, Yasunori, Bessho, Kazuhisa, ...
The aim of this study was to examine the potential of immunoselected genetically modified human osteoprogenitors to form bone in vivo on porous PLA scaffolds. Human osteoprogenitors from bone marrow...
Partridge, Kris, Yang, Xuebin, Clarke, Nicholas M.P., Okubo, Yasunori, Bessho, Kazuhisa, Sebald, Walter, ...
The aim of this study was to determine the feasibility of adenoviral gene transfer into primary human bone marrow osteoprogenitor cells in combination with biodegradeable scaffolds to tissue-engineer...
Spectroscopy in liquefied and supercritical noble gases. (1989)
Thesis (Ph. D.)--University of Nottingham, 1989.
Spectroscopy in liquefied and supercritical noble gases [microform] / (1989)
BLDSC reference no.: D89335.
Mammalian cell survival and processing in supercritical CO2
Ginty, Patrick J., Howard, Daniel, Whitaker, Martin J., Barry, John J. A., Tighe, Patrick, ...
We demonstrate that mammalian cells can survive for 5 min within high-pressure CO2. Cell survival was investigated by exposing a range of mammalian cell types to supercritical CO2 (scCO2) (35°C, 74...
Mammalian cell survival and processing in supercritical CO2
Ginty, Patrick J., Howard, Daniel, Whitaker, Martin J., Barry, John J. A., Tighe, Patrick, ...
We demonstrate that mammalian cells can survive for 5 min within high-pressure CO2. Cell survival was investigated by exposing a range of mammalian cell types to supercritical CO2 (scCO2) (35°C, 74...
Supercritical carbon dioxide: putting the fizz into biomaterials
Barry, John J.A., Popov, Vladimir K., Shakesheff, Kevin M., Howdle, Steven M.
This paper describes recent progress made in the use of high pressure or supercritical fluids to process polymers into three-dimensional tissue engineering scaffolds. Three current examples are...