Phi29 polymerase based random amplification of viral RNA as an alternative to random RT-PCR (2008)
Berthet, Nicolas, Reinhardt, Anita K, Leclercq, India, Van Ooyen, Sven, Batéjat, Christophe, Dickinson, Philip, ...
Abstract Background Phi29 polymerase based amplification methods provides amplified DNA with minimal changes in sequence and relative abundance for many biomedical applications. RNA virus detection...
Mole � culaire Bacte � rienne, (2008)
Donne Es (pt, Ge Nopole, Mycobacterium Tuberculosis Hrv, Jean-christophe Camus, Melinda J. Pryor, Claudine Me Digue, ...
2 Annotation-Bases de
Control of M. tuberculosis ESAT-6 Secretion and Specific T Cell Recognition by PhoP (2008)
Wafa Frigui, Daria Bottai, Laleh Majlessi, Marc Monot, Emmanuelle Josselin, Priscille Brodin, ...
Analysis of mycobacterial strains that have lost their ability to cause disease is a powerful approach to identify yet unknown virulence determinants and pathways involved in tuberculosis...
Stinear, Timothy P., Seemann, Torsten, Harrison, Paul F., Jenkin, Grant A., Davies, John K., Johnson, Paul D.R., ...
Mycobacterium marinum, a ubiquitous pathogen of fish and amphibia, is a near relative of Mycobacterium tuberculosis, the etiologic agent of tuberculosis in humans. The genome of the M strain of M....
Multiplex Sequencing of 1.5 Mb of the Mycobacterium leprae Genome (2007)
Douglas R. Smith, Peter Richterich, Marc Rubenfield, Philip W. Rice, Kathleen Falls, Joan Imrich, ...
The nucleotide sequence of 1.5 Mb of genomic DNA from Mycobacterium leprae was determined using computer-assisted multiplex sequencing technology. This brings the 2.8-Mb M. leprae genome sequence to...
Graña, Martin, Haouz, Ahmed, Buschiazzo, Alejandro, Miras, Isabelle, Wehenkel, Annemarie, Bondet, Vincent, ...
Mycobacterium leprae protein ML2640c belongs to a large family of conserved hypothetical proteins predominantly found in mycobacteria, some of them predicted as putative S-adenosylmethionine...
Laurent Marsollier, Priscille Brodin, Mary Jackson, Jana Korduláková, Petra Tafelmeyer, Etienne Carbonnelle, ...
The role of biofilms in the pathogenesis of mycobacterial diseases remains largely unknown. Mycobacterium ulcerans, the etiological agent of Buruli ulcer, a disfiguring disease in humans, adopts a...
Laurent Marsollier, Estelle Deniaux, Priscille Brodin, Agnès Marot, Christelle Mbondji Wondje, ...
BackgroundBuruli ulcer is a severe human skin disease caused by Mycobacterium ulcerans. This disease is primarily diagnosed in West Africa with increasing incidence. Antimycobacterial drug therapy is...
Mycobacterium Tuberculosis Hra, Nathalie Barilone, Frédéric Boudou, Jesús Gonzalo Asensio, Carlos Martín, ...
Similarities between Mycobacterium tuberculosis phoP-phoR mutants and the attenuated laboratory strain M. tuberculosis H37Ra in terms of morphological and cytochemical properties, lipid content, gene...
Stinear, Timothy P., Seemann, Torsten, Pidot, Sacha, Frigui, Wafa, Reysset, Gilles, Garnier, Thierry, ...
Mycobacterium ulcerans is found in aquatic ecosystems and causes Buruli ulcer in humans, a neglected but devastating necrotic disease of subcutaneous tissue that is rampant throughout West and...
Proteome Analysis of the Plasma Membrane of Mycobacterium Tuberculosis (2006)
Sudhir Sinha, Shalini Arora, K. Kosalai, Abdelkader Namane, Alex S. Pym, Stewart T. Cole
The plasma membrane of Mycobacterium tuberculosis is likely to contain proteins that could serve as novel drug targets, diagnostic probes or even components of a vaccine against tuberculosis. With...
Antigen discovery: a postgenomic approach to leprosy diagnosis. (2006)
Aráoz, Romulo, Honoré, Nadine, Cho, Sungae, Kim, Jong-Pill, Cho, Sang-Nae, Monot, Marc, ...
Leprosy is an infectious, neurodegenerative disease of humans caused by Mycobacterium leprae. Despite effective control programs, the incidence of leprosy remains stubbornly high, suggesting that...
Antigen discovery: a postgenomic approach to leprosy diagnosis. (2006)
Aráoz, Romulo, Honoré, Nadine, Cho, Sungae, Kim, Jong-Pill, Cho, Sang-Nae, Monot, Marc, ...
Leprosy is an infectious, neurodegenerative disease of humans caused by Mycobacterium leprae. Despite effective control programs, the incidence of leprosy remains stubbornly high, suggesting that...
Mycobacterium tuberculosis and the host response (2005)
Kaufmann, Stefan H. E., Cole, Stewart T., Mizrahi, Valerie, Rubin, Eric, Nathan, Carl
Williams, Ann, Hatch, Graham J., Clark, Simon O., Gooch, Karen E., Hatch, Kim A., Hall, Graham A., ...
Proteome Analysis of the Plasma Membrane of Mycobacterium tuberculosis (2002)
Sudhir Sinha, Shalini Arora, K. Kosalai, Abdelkader Namane, Alex S. Pym, Stewart T. Cole
The plasma membrane of Mycobacterium tuberculosis is likely to contain proteins that could serve as novel drug targets, diagnostic probes or even components of a vaccine against tuberculosis. With...
Saint-Joanis, Brigitte, Souchon, Helene, Wilming, Martin, Johnsson, Kai, Alzari, Pedro M., Cole, Stewart T.
A series of mutants bearing single amino acid substitutions often encountered in the catalase/peroxidase, KatG, from isoniazid-resistant isolates of Mycobacterium tuberculosis has been produced by...
Multiplex Sequencing of 1.5 Mb of the Mycobacterium leprae Genome (1997)
Smith, Douglas R., Richterich, Peter, Rubenfield, Marc, Rice, Philip W., Butler, Carol, Lee, Hong-Mei, ...
Honoré, Nadine, Cole, Stewart T.
DNA databank accession numbers were omitted from two articles published in Volume 18 issue number 3. The complete titles are published below.
The nucleotide sequence coding for major outer membrane protein OmpA of Shigella dysenteriae (1982)
The nucleotide sequence of the ompA gene from Shigella dysenteriae has been determined and the amino acid sequence of the pro-OmpA protein predicted. Sequence comparison between the ompA genes of...
Brosch, Roland, Philipp, Wolfgang J., Stavropoulos, Evangelos, Colston, M. Joseph, Cole, Stewart T., Gordon, Stephen V.
Mycobacterium tuberculosis H37Ra is an attenuated tubercle bacillus closely related to the virulent type strain M. tuberculosis H37Rv. Despite extensive study, the reason for the decreased virulence...
Brosch, Roland, Phillipp, Wolfgang J., Stavropoulos, Evangelos, Colston, M. Joseph, Cole, Stewart T., Gordon, Stephen V.
Brosch, Roland, Gordon, Stephen V., Billault, Alain, Garnier, Thierry, Eiglmeier, Karin, Soravito, Catherine, ...
The bacterial artificial chromosome (BAC) cloning system is capable of stably propagating large, complex DNA inserts in Escherichia coli. As part of the Mycobacterium tuberculosis H37Rv genome...
Silbaq, Fauzi S., Cho, Sang-Nae, Cole, Stewart T., Brennan, Patrick J.
During DNA sequence analysis of cosmid L373 from the Mycobacterium leprae genome, an open reading frame of 1.4 kb encoding a protein with some homology to the immunodominant 34-kDa protein of...
Parsons, Linda M., Brosch, Roland, Cole, Stewart T., Somoskövi, Ákos, Loder, Arthur, Bretzel, Gisela, ...
Although the virulences and host ranges differ among members of the Mycobacterium tuberculosis complex (TBC; M. tuberculosis, M. africanum, M. canettii, M. microti, M. bovis, and M. bovis BCG),...
Pym, Alexander S., Saint-Joanis, Brigitte, Cole, Stewart T.
The usefulness of isoniazid (INH), a key component of short-course chemotherapy of tuberculosis, is threatened by the emergence of drug-resistant strains of Mycobacterium tuberculosis with mutations...
Brodin, Priscille, Eiglmeier, Karin, Marmiesse, Magali, Billault, Alain, Garnier, Thierry, Niemann, Stefan, ...
Mycobacterium microti is a member of the Mycobacterium tuberculosis complex that causes tuberculosis in voles. Most strains of M. microti are harmless for humans, and some have been successfully used...
Marsollier, Laurent, Honoré, Nadine, Legras, Pierre, Manceau, Anne Lise, Kouakou, Henri, Carbonnelle, Bernard, ...
By use of a murine model for Buruli ulcer, Mycobacterium ulcerans was found to be susceptible to rifampin, with the MIC being 0.5 to 1 μg/ml. Three mutants were isolated after rifampin monotherapy....
The complete genome sequence of Mycobacterium bovis
Garnier, Thierry, Eiglmeier, Karin, Camus, Jean-Christophe, Medina, Nadine, Mansoor, Huma, Pryor, Melinda, ...
Mycobacterium bovis is the causative agent of tuberculosis in a range of animal species and man, with worldwide annual losses to agriculture of $3 billion. The human burden of tuberculosis caused by...
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans
Stinear, Timothy P., Mve-Obiang, Armand, Small, Pamela L. C., Frigui, Wafa, Pryor, Melinda J., Brosch, Roland, ...
Mycobacterium ulcerans (MU), an emerging human pathogen harbored by aquatic insects, is the causative agent of Buruli ulcer, a devastating skin disease rife throughout Central and West Africa....
Genotypic Analysis of Mycobacterium tuberculosis in Bangladesh and Prevalence of the Beijing Strain
Banu, Sayera, Gordon, Stephen V., Palmer, Si, Islam, Reazul, Ahmed, Shakeel, Alam, Khan Mashrequl, ...
Genotypic analysis was performed on 48 Mycobacterium tuberculosis complex strains collected from a hospital in Dhaka city. Deletion analysis showed that the isolates were all M. tuberculosis; 13 of...
Demangel, Caroline, Brodin, Priscille, Cockle, Paul J., Brosch, Roland, Majlessi, Laleh, Leclerc, Claude, ...
The protective efficacy of Mycobacterium bovis BCG can be markedly augmented by stable integration of Mycobacterium tuberculosis genomic region RD1. BCG complemented with RD1 (BCG::RD1) encodes nine...
Genotypic Analysis of Mycobacterium tuberculosis in Bangladesh and Prevalence of the Beijing Strain
Banu*, Sayera, Gordon, Stephen V., Palmer, Si, Islam, M. Riazul, Ahmed, Shakeel, Alam, Khan Mashrequl, ...
Spencer, John S., Kim, Hee Jin, Marques, Angela M., Gonzalez-Juarerro, Mercedes, Vissa, Varalakshmi D., ...
Culture filtrate protein 10 (CFP-10) from Mycobacterium tuberculosis is a well-characterized immunodominant 10-kDa protein antigen known to elicit a very potent early gamma interferon response in T...
Aquatic Snails, Passive Hosts of Mycobacterium ulcerans
Marsollier, Laurent, Sévérin, Tchibozo, Aubry, Jacques, Merritt, Richard W., Saint André, Jean-Paul, Legras, Pierre, ...
Accumulative indirect evidence of the epidemiology of Mycobacterium ulcerans infections causing chronic skin ulcers (i.e., Buruli ulcer disease) suggests that the development of this pathogen and its...
Stinear, Timothy P., Hong, Hui, Frigui, Wafa, Pryor, Melinda J., Brosch, Roland, Garnier, Thierry, ...
The 174-kb virulence plasmid pMUM001 in Mycobacterium ulcerans epidemic strain Agy99 harbors three very large and homologous genes that encode giant polyketide synthases (PKS) responsible for the...
Demangel, Caroline, Garnier, Thierry, Rosenkrands, Ida, Cole, Stewart T.
In silico analysis reveals that most protective antigens expressed by the antituberculous vaccine Mycobacterium bovis BCG (BCG) are conserved in M. avium, supporting the hypothesis that exposure to...
Antigen Discovery: a Postgenomic Approach to Leprosy Diagnosis
Aráoz, Romulo, Honoré, Nadine, Cho, Sungae, Kim, Jong-Pill, Cho, Sang-Nae, Monot, Marc, ...
Leprosy is an infectious, neurodegenerative disease of humans caused by Mycobacterium leprae. Despite effective control programs, the incidence of leprosy remains stubbornly high, suggesting that...
Brodin, Priscille, Majlessi, Laleh, Marsollier, Laurent, De Jonge, Marien I., Bottai, Daria, Demangel, Caroline, ...
The dedicated secretion system ESX-1 of Mycobacterium tuberculosis encoded by the extended RD1 region (extRD1) assures export of the ESAT-6 protein and its partner, the 10-kDa culture filtrate...
Majlessi, Laleh, Simsova, Marcela, Jarvis, Zdenka, Brodin, Priscille, Rojas, Marie-Jésus, Bauche, Cécile, ...
Bordetella pertussis adenylate cyclase (CyaA) toxoid is a powerful nonreplicative immunization vector targeting dendritic cells, which has already been used successfully in prophylactic and...
Brosch, Roland, Philipp, Wolfgang J., Stavropoulos, Evangelos, Colston, M. Joseph, Cole, Stewart T., Gordon, Stephen V.
Mycobacterium tuberculosis H37Ra is an attenuated tubercle bacillus closely related to the virulent type strain M. tuberculosis H37Rv. Despite extensive study, the reason for the decreased virulence...
Brosch, Roland, Phillipp, Wolfgang J., Stavropoulos, Evangelos, Colston, M. Joseph, Cole, Stewart T., Gordon, Stephen V.
Brosch, Roland, Gordon, Stephen V., Billault, Alain, Garnier, Thierry, Eiglmeier, Karin, Soravito, Catherine, ...
The bacterial artificial chromosome (BAC) cloning system is capable of stably propagating large, complex DNA inserts in Escherichia coli. As part of the Mycobacterium tuberculosis H37Rv genome...
Silbaq, Fauzi S., Cho, Sang-Nae, Cole, Stewart T., Brennan, Patrick J.
During DNA sequence analysis of cosmid L373 from the Mycobacterium leprae genome, an open reading frame of 1.4 kb encoding a protein with some homology to the immunodominant 34-kDa protein of...
Parsons, Linda M., Brosch, Roland, Cole, Stewart T., Somoskövi, Ákos, Loder, Arthur, Bretzel, Gisela, ...
Although the virulences and host ranges differ among members of the Mycobacterium tuberculosis complex (TBC; M. tuberculosis, M. africanum, M. canettii, M. microti, M. bovis, and M. bovis BCG),...
Pym, Alexander S., Saint-Joanis, Brigitte, Cole, Stewart T.
The usefulness of isoniazid (INH), a key component of short-course chemotherapy of tuberculosis, is threatened by the emergence of drug-resistant strains of Mycobacterium tuberculosis with mutations...
Brodin, Priscille, Eiglmeier, Karin, Marmiesse, Magali, Billault, Alain, Garnier, Thierry, Niemann, Stefan, ...
Mycobacterium microti is a member of the Mycobacterium tuberculosis complex that causes tuberculosis in voles. Most strains of M. microti are harmless for humans, and some have been successfully used...
Marsollier, Laurent, Honoré, Nadine, Legras, Pierre, Manceau, Anne Lise, Kouakou, Henri, Carbonnelle, Bernard, ...
By use of a murine model for Buruli ulcer, Mycobacterium ulcerans was found to be susceptible to rifampin, with the MIC being 0.5 to 1 μg/ml. Three mutants were isolated after rifampin monotherapy....
The complete genome sequence of Mycobacterium bovis
Garnier, Thierry, Eiglmeier, Karin, Camus, Jean-Christophe, Medina, Nadine, Mansoor, Huma, Pryor, Melinda, ...
Mycobacterium bovis is the causative agent of tuberculosis in a range of animal species and man, with worldwide annual losses to agriculture of $3 billion. The human burden of tuberculosis caused by...
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans
Stinear, Timothy P., Mve-Obiang, Armand, Small, Pamela L. C., Frigui, Wafa, Pryor, Melinda J., Brosch, Roland, ...
Mycobacterium ulcerans (MU), an emerging human pathogen harbored by aquatic insects, is the causative agent of Buruli ulcer, a devastating skin disease rife throughout Central and West Africa....
Genotypic Analysis of Mycobacterium tuberculosis in Bangladesh and Prevalence of the Beijing Strain
Banu, Sayera, Gordon, Stephen V., Palmer, Si, Islam, Reazul, Ahmed, Shakeel, Alam, Khan Mashrequl, ...
Genotypic analysis was performed on 48 Mycobacterium tuberculosis complex strains collected from a hospital in Dhaka city. Deletion analysis showed that the isolates were all M. tuberculosis; 13 of...
Demangel, Caroline, Brodin, Priscille, Cockle, Paul J., Brosch, Roland, Majlessi, Laleh, Leclerc, Claude, ...
The protective efficacy of Mycobacterium bovis BCG can be markedly augmented by stable integration of Mycobacterium tuberculosis genomic region RD1. BCG complemented with RD1 (BCG::RD1) encodes nine...
Genotypic Analysis of Mycobacterium tuberculosis in Bangladesh and Prevalence of the Beijing Strain
Banu*, Sayera, Gordon, Stephen V., Palmer, Si, Islam, M. Riazul, Ahmed, Shakeel, Alam, Khan Mashrequl, ...
Spencer, John S., Kim, Hee Jin, Marques, Angela M., Gonzalez-Juarerro, Mercedes, Vissa, Varalakshmi D., ...
Culture filtrate protein 10 (CFP-10) from Mycobacterium tuberculosis is a well-characterized immunodominant 10-kDa protein antigen known to elicit a very potent early gamma interferon response in T...
Aquatic Snails, Passive Hosts of Mycobacterium ulcerans
Marsollier, Laurent, Sévérin, Tchibozo, Aubry, Jacques, Merritt, Richard W., Saint André, Jean-Paul, Legras, Pierre, ...
Accumulative indirect evidence of the epidemiology of Mycobacterium ulcerans infections causing chronic skin ulcers (i.e., Buruli ulcer disease) suggests that the development of this pathogen and its...
Stinear, Timothy P., Hong, Hui, Frigui, Wafa, Pryor, Melinda J., Brosch, Roland, Garnier, Thierry, ...
The 174-kb virulence plasmid pMUM001 in Mycobacterium ulcerans epidemic strain Agy99 harbors three very large and homologous genes that encode giant polyketide synthases (PKS) responsible for the...
Demangel, Caroline, Garnier, Thierry, Rosenkrands, Ida, Cole, Stewart T.
In silico analysis reveals that most protective antigens expressed by the antituberculous vaccine Mycobacterium bovis BCG (BCG) are conserved in M. avium, supporting the hypothesis that exposure to...
Antigen Discovery: a Postgenomic Approach to Leprosy Diagnosis
Aráoz, Romulo, Honoré, Nadine, Cho, Sungae, Kim, Jong-Pill, Cho, Sang-Nae, Monot, Marc, ...
Leprosy is an infectious, neurodegenerative disease of humans caused by Mycobacterium leprae. Despite effective control programs, the incidence of leprosy remains stubbornly high, suggesting that...
Brodin, Priscille, Majlessi, Laleh, Marsollier, Laurent, De Jonge, Marien I., Bottai, Daria, Demangel, Caroline, ...
The dedicated secretion system ESX-1 of Mycobacterium tuberculosis encoded by the extended RD1 region (extRD1) assures export of the ESAT-6 protein and its partner, the 10-kDa culture filtrate...
Majlessi, Laleh, Simsova, Marcela, Jarvis, Zdenka, Brodin, Priscille, Rojas, Marie-Jésus, Bauche, Cécile, ...
Bordetella pertussis adenylate cyclase (CyaA) toxoid is a powerful nonreplicative immunization vector targeting dendritic cells, which has already been used successfully in prophylactic and...
Saint-Joanis, Brigitte, Demangel, Caroline, Jackson, Mary, Brodin, Priscille, Marsollier, Laurent, Boshoff, Helena, ...
The twin arginine translocation (Tat) system is used by many bacteria to export fully folded proteins containing cofactors. Here, we show genetically that this system is essential for Mycobacterium...
The Ser/Thr Protein Kinase PknB Is Essential for Sustaining Mycobacterial Growth▿
Fernandez, Pablo, Saint-Joanis, Brigitte, Barilone, Nathalie, Jackson, Mary, Gicquel, Brigitte, Cole, Stewart T., ...
The receptor-like protein kinase PknB from Mycobacterium tuberculosis is encoded by the distal gene in a highly conserved operon, present in all actinobacteria, that may control cell shape and cell...
Protection against Mycobacterium ulcerans Lesion Development by Exposure to Aquatic Insect Saliva
Marsollier, Laurent, Deniaux, Estelle, Brodin, Priscille, Marot, Agnès, Wondje, Christelle Mbondji, Saint-André, Jean-Paul, ...
Saliva from aquatic insects in areas where Buruli ulcer is endemic can protect mice against the disease's characteristic skin lesion and might play a role in natural immunity in humans.
Marsollier, Laurent, Brodin, Priscille, Jackson, Mary, Korduláková, Jana, Tafelmeyer, Petra, Carbonnelle, Etienne, ...
The role of biofilms in the pathogenesis of mycobacterial diseases remains largely unknown. Mycobacterium ulcerans, the etiological agent of Buruli ulcer, a disfiguring disease in humans, adopts a...
Shepard, William, Haouz, Ahmed, Graña, Martin, Buschiazzo, Alejandro, Betton, Jean-Michel, Cole, Stewart T., ...
The gene Rv0813c from Mycobacterium tuberculosis, which codes for a hypothetical protein of unknown function, is conserved within the order Actinomycetales but absent elsewhere. The crystal structure...
Stinear, Timothy P., Seemann, Torsten, Pidot, Sacha, Frigui, Wafa, Reysset, Gilles, Garnier, Thierry, ...
Mycobacterium ulcerans is found in aquatic ecosystems and causes Buruli ulcer in humans, a neglected but devastating necrotic disease of subcutaneous tissue that is rampant throughout West and...
Genome plasticity of BCG and impact on vaccine efficacy
Brosch, Roland, Gordon, Stephen V., Garnier, Thierry, Eiglmeier, Karin, Frigui, Wafa, Valenti, Philippe, ...
To understand the evolution, attenuation, and variable protective efficacy of bacillus Calmette–Guérin (BCG) vaccines, Mycobacterium bovis BCG Pasteur 1173P2 has been subjected to comparative...
New Approaches to Filling the Gap in Tuberculosis Drug Discovery
Casenghi, Martina, Cole, Stewart T, Nathan, Carl F
For the first time in decades, say the authors, there is a tuberculosis drug pipeline, but the paucity of candidates is still cause for alarm.
De Jonge, Marien I., Pehau-Arnaudet, Gérard, Fretz, Marjan M., Romain, Felix, Bottai, Daria, Brodin, Priscille, ...
The 6-kDa early secreted antigenic target ESAT-6 and the 10-kDa culture filtrate protein CFP-10 of Mycobacterium tuberculosis are secreted by the ESX-1 system into the host cell and thereby...
Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone
Coutanceau, Emmanuelle, Decalf, Jeremie, Martino, Angelo, Babon, Aurélie, Winter, Nathalie, Cole, Stewart T., ...
Mycolactone is a polyketide toxin produced by Mycobacterium ulcerans (Mu), the causative agent of the skin disease Buruli ulcer (BU). Surprisingly, infected tissues lack inflammatory infiltrates....
Mycobacterium tuberculosis and the host response
Kaufmann, Stefan H.E., Cole, Stewart T., Mizrahi, Valerie, Rubin, Eric, Nathan, Carl
Mycobacterium tuberculosis remains a leading cause of morbidity and mortality worldwide. Advances reported at a recent international meeting highlight insights and controversies in the genetics of M....
Control of M. tuberculosis ESAT-6 Secretion and Specific T Cell Recognition by PhoP
Frigui, Wafa, Bottai, Daria, Majlessi, Laleh, Monot, Marc, Josselin, Emmanuelle, Brodin, Priscille, ...
Analysis of mycobacterial strains that have lost their ability to cause disease is a powerful approach to identify yet unknown virulence determinants and pathways involved in tuberculosis...
Chesne-Seck, Marie-Laure, Barilone, Nathalie, Boudou, Frédéric, Asensio, Jesús Gonzalo, Kolattukudy, Pappachan E., Martín, Carlos, ...
Similarities between Mycobacterium tuberculosis phoP-phoR mutants and the attenuated laboratory strain M. tuberculosis H37Ra in terms of morphological and cytochemical properties, lipid content, gene...
Brosch, Roland, Gordon, Stephen V., Buchrieser, Carmen, Pym, Alexander S., Garnier, Thierry, Cole, Stewart T.
On direct comparison of minimal sets of ordered clones from bacterial artificial chromosome (BAC) libraries representing the complete genomes of Mycobacterium tuberculosis H37Rv and the vaccine...
Proteome Analysis of the Plasma Membrane of Mycobacterium Tuberculosis
Sinha, Sudhir, Arora, Shalini, Kosalai, K., Namane, Abdelkader, Pym, Alex S., Cole, Stewart T.
The plasma membrane of Mycobacterium tuberculosis is likely to contain proteins that could serve as novel drug targets, diagnostic probes or even components of a vaccine against tuberculosis. With...
Phi29 polymerase based random amplification of viral RNA as an alternative to random RT-PCR
Berthet, Nicolas, Reinhardt, Anita K, Leclercq, India, Van Ooyen, Sven, Batéjat, Christophe, Dickinson, Philip, ...
Graña, Martin, Haouz, Ahmed, Buschiazzo, Alejandro, Miras, Isabelle, Wehenkel, Annemarie, Bondet, Vincent, ...
Mycobacterium leprae protein ML2640c belongs to a large family of conserved hypothetical proteins predominantly found in mycobacteria, some of them predicted as putative S-adenosylmethionine...
Stinear, Timothy P., Seemann, Torsten, Harrison, Paul F., Jenkin, Grant A., Davies, John K., Johnson, Paul D.R., ...
Mycobacterium marinum, a ubiquitous pathogen of fish and amphibia, is a near relative of Mycobacterium tuberculosis, the etiologic agent of tuberculosis in humans. The genome of the M strain of M....
Are Variable-Number Tandem Repeats Appropriate for Genotyping Mycobacterium leprae?▿
Monot, Marc, Honoré, Nadine, Balière, Charlotte, Ji, Baohong, Sow, Samba, Brennan, Patrick J., ...
Comparative genomics analysis of the Tamil Nadu strain of Mycobacterium leprae has uncovered several polymorphic sites with potential as epidemiological tools. In this study we compared the stability...
Systematic Genetic Nomenclature for Type VII Secretion Systems
Bitter, Wilbert, Houben, Edith N. G., Bottai, Daria, Brodin, Priscille, Brown, Eric J., Cox, Jeffery S., ...
Christophe, Thierry, Jackson, Mary, Jeon, Hee Kyoung, Fenistein, Denis, Contreras-Dominguez, Monica, Kim, Jaeseung, ...
A critical feature of Mycobacterium tuberculosis, the causative agent of human tuberculosis (TB), is its ability to survive and multiply within macrophages, making these host cells an ideal niche for...
Garcia Pelayo, M. Carmen, Uplekar, Swapna, Keniry, Andrew, Mendoza Lopez, Pablo, Garnier, Thierry, Nunez Garcia, Javier, ...
To further unravel the mechanisms responsible for attenuation of the tuberculosis vaccine Mycobacterium bovis BCG, comparative genomics was used to identify single nucleotide polymorphisms (SNPs)...
McLean, Kirsty J., Carroll, Paul, Lewis, D. Geraint, Dunford, Adrian J., Seward, Harriet E., Neeli, Rajasekhar, ...
Mycobacterium tuberculosis (Mtb) cytochrome P450 gene CYP121 is shown to be essential for viability of the bacterium in vitro by gene knock-out with complementation. Production of CYP121 protein in...