Christopher J. Tonkin, Céline K. Carret, Manoj T. Duraisingh, Till S. Voss, Stuart A. Ralph, Mirja Hommel, ...
Cytoadherance of Plasmodium falciparum-infected erythrocytes in the brain, organs and peripheral microvasculature is linked to morbidity and mortality associated with severe malaria. Parasite-derived...
falciparum antigens by antigenic analysis of genomic and proteomic (2006)
Z. Bozdech, M. Llinas, B. L. Pulliam, E. D. Wong, J. Zhu, Z. Bozdech, ...
plasmodium
Ralph, Stuart A, Bischoff, Emmanuel, Mattei, Denise, Sismeiro, Odile, Dillies, Marie-Agnès, Guigon, Ghislaine, ...
Abstract Background Plasmodium falciparum , the causative agent of the most severe form of malaria, undergoes antigenic variation through successive presentation of a family of antigens on the...
Evolutionary Pressures on Apicoplast Transit Peptides (2004)
Ralph, Stuart A., Foth, Bernardo J., Hall, Neil, McFadden, Geoffrey I.
Malaria parasites (species of the genus Plasmodium) harbour a relict chloroplast (the apicoplast) that is the target of novel anti-malarials. Numerous nuclear-encoded proteins are translocated into...
Evolutionary Pressures on Apicoplast Transit Peptides (2004)
Ralph, Stuart A., Foth, Bernardo J., Hall, Neil, McFadden, Geoffrey I.
Malaria parasites (species of the genus Plasmodium) harbor a relict chloroplast (the apicoplast) that is the target of novel antimalarials. Numerous nuclear-encoded proteins are translocated into the...
Evolutionary Pressures on Apicoplast Transit Peptides (2004)
Ralph, Stuart A., Foth, Bernardo J., Hall, Neil, McFadden, Geoffrey I.
Malaria parasites (species of the genus Plasmodium) harbour a relict chloroplast (the apicoplast) that is the target of novel anti-malarials. Numerous nuclear-encoded proteins are translocated into...
Dissecting the apicoplast targeting in the malaria parasite Plasmodium falciparum (2003)
FOTH, BERNARDO JAVIER, RALPH, STUART A, TONKIN, CHRISTOPHER JOHN, STRUCK, NICOLE SUNAINA, FRAUNHOLZ, MARTIN, ROOS, DAVID, ...
Properties and prediction of mitochondrial transit peptides from Plasmodium falciparum (2003)
BENDER, ANDREAS, VAN DOOREN, GIEL GODEFRIDUS, RALPH, STUART A, MCFADDEN, GEOFFREY IAN, SCHNEIDER, GISBERT
Dissecting the apicoplast targeting in the malaria parasite Plasmodium falciparum (2003)
FOTH, BERNARDO JAVIER, RALPH, STUART A, TONKIN, CHRISTOPHER JOHN, STRUCK, NICOLE SUNAINA, FRAUNHOLZ, MARTIN, ROOS, DAVID, ...
Properties and prediction of mitochondrial transit peptides from Plasmodium falciparum (2003)
BENDER, ANDREAS, VAN DOOREN, GIEL GODEFRIDUS, RALPH, STUART A, MCFADDEN, GEOFFREY IAN, SCHNEIDER, GISBERT
Wickham, Mark E., Rug, Melanie, Ralph, Stuart A., Klonis, Nectarios, McFadden, Geoffrey I., Tilley, Leann, ...
After invading human erythrocytes, the malarial parasite Plasmodium falciparum, initiates a remarkable process of secreting proteins into the surrounding erythrocyte cytoplasm and plasma membrane....
A Type II Pathway for Fatty Acid Biosynthesis Presents Drug Targets in Plasmodium falciparum
Waller, Ross F., Ralph, Stuart A., Reed, Michael B., Su, Vanessa, Douglas, James D., Minnikin, David E., ...
It has long been held that the malaria parasite, Plasmodium sp., is incapable of de novo fatty acid synthesis. This view has recently been overturned with the emergence of data for the presence of a...
Duraisingh, Manoj T., Triglia, Tony, Ralph, Stuart A., Rayner, Julian C., Barnwell, John W., McFadden, Geoffrey I., ...
The members of the phylum Apicomplexa parasitize a wide range of eukaryotic host cells. Plasmodium falciparum, responsible for the most virulent form of malaria, invades human erythrocytes using...
Ralph, Stuart A., Scheidig-Benatar, Christine, Scherf, Artur
Much of the success of Plasmodium falciparum in establishing persistent infections is attributed to immune evasion through antigenic variation. This process involves periodically exchanging variants...
Ralph, Stuart A, Bischoff, Emmanuel, Mattei, Denise, Sismeiro, Odile, Dillies, Marie-Agnès, Guigon, Ghislaine, ...
A microarray analysis of Plasmodium falciparum selected to express different var genes suggests that antisense transcripts are not responsible for the transcriptional silencing of non-expressed var...
Membrane transporters in the relict plastid of malaria parasites
Mullin, Kylie A., Lim, Liting, Ralph, Stuart A., Spurck, Timothy P., Handman, Emanuela, McFadden, Geoffrey I.
Malaria parasites contain a nonphotosynthetic plastid homologous to chloroplasts of plants. The parasite plastid synthesizes fatty acids, heme, iron sulfur clusters and isoprenoid precursors and is...
Wickham, Mark E., Rug, Melanie, Ralph, Stuart A., Klonis, Nectarios, McFadden, Geoffrey I., Tilley, Leann, ...
After invading human erythrocytes, the malarial parasite Plasmodium falciparum, initiates a remarkable process of secreting proteins into the surrounding erythrocyte cytoplasm and plasma membrane....
A Type II Pathway for Fatty Acid Biosynthesis Presents Drug Targets in Plasmodium falciparum
Waller, Ross F., Ralph, Stuart A., Reed, Michael B., Su, Vanessa, Douglas, James D., Minnikin, David E., ...
It has long been held that the malaria parasite, Plasmodium sp., is incapable of de novo fatty acid synthesis. This view has recently been overturned with the emergence of data for the presence of a...
Duraisingh, Manoj T., Triglia, Tony, Ralph, Stuart A., Rayner, Julian C., Barnwell, John W., McFadden, Geoffrey I., ...
The members of the phylum Apicomplexa parasitize a wide range of eukaryotic host cells. Plasmodium falciparum, responsible for the most virulent form of malaria, invades human erythrocytes using...
Ralph, Stuart A., Scheidig-Benatar, Christine, Scherf, Artur
Much of the success of Plasmodium falciparum in establishing persistent infections is attributed to immune evasion through antigenic variation. This process involves periodically exchanging variants...
Ralph, Stuart A, Bischoff, Emmanuel, Mattei, Denise, Sismeiro, Odile, Dillies, Marie-Agnès, Guigon, Ghislaine, ...
A microarray analysis of Plasmodium falciparum selected to express different var genes suggests that antisense transcripts are not responsible for the transcriptional silencing of non-expressed var...
Evolution of malaria parasite plastid targeting sequences
Tonkin, Christopher J., Foth, Bernardo J., Ralph, Stuart A., Struck, Nicole, Cowman, Alan F., McFadden, Geoffrey I.
The transfer of genes from an endosymbiont to its host typically requires acquisition of targeting signals by the gene product to ensure its return to the endosymbiont for function. Many hundreds of...
Tonkin, Christopher J, Carret, Céline K, Duraisingh, Manoj T, Voss, Till S, Ralph, Stuart A, Hommel, Mirja, ...
Cytoadherance of Plasmodium falciparum-infected erythrocytes in the brain, organs and peripheral microvasculature is linked to morbidity and mortality associated with severe malaria. Parasite-derived...
Theileria Apicoplast as a Target for Chemotherapy▿ †
Lizundia, Regina, Werling, Dirk, Langsley, Gordon, Ralph, Stuart A.
Theileria parasites cause severe bovine disease and death in a large part of the world. These apicomplexan parasites possess a relic plastid (apicoplast), whose metabolic pathways include several...
Flueck, Christian, Bartfai, Richard, Volz, Jennifer, Niederwieser, Igor, Salcedo-Amaya, Adriana M., Alako, Blaise T. F., ...
Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The malaria parasite Plasmodium falciparum employs antigenic variation of the major surface antigen PfEMP1, encoded...