Lv2, a Novel Postentry Restriction, Is Mediated by both Capsid and Envelope
Schmitz, Christian, Marchant, David, Neil, Stuart J. D., Aubin, Keith, Reuter, Sandra, Dittmar, Matthias T., ...
The characterization of restrictions to lentivirus replication in cells identifies critical steps in the viral life cycle and potential therapeutic targets. We previously reported that a human...
Neil, Stuart J. D., Clapham, Paul R., Nibbs, Robert J., McKnight, Áine, Weiss, Robin A.
The role of coreceptors other than CCR5 and CXCR4 in the pathogenesis of human immunodeficiency virus (HIV) disease is controversial. Here we show that a promiscuous CC chemokine receptor, D6, can...
Marchant, David, Neil, Stuart J. D., Aubin, Keith, Schmitz, Christian, McKnight, Áine
We identified a postentry restriction, termed Lv2, which determines the cellular tropism of two related human immunodeficiency virus type 2 (HIV-2) isolates and is dependent on the sequence of the...
Neil, Stuart J. D, Eastman, Scott W, Jouvenet, Nolwenn, Bieniasz, Paul D
The human immunodeficiency virus (HIV) type-1 viral protein U (Vpu) protein enhances the release of diverse retroviruses from human, but not monkey, cells and is thought to do so by ablating a...
Lv2, a Novel Postentry Restriction, Is Mediated by both Capsid and Envelope
Schmitz, Christian, Marchant, David, Neil, Stuart J. D., Aubin, Keith, Reuter, Sandra, Dittmar, Matthias T., ...
The characterization of restrictions to lentivirus replication in cells identifies critical steps in the viral life cycle and potential therapeutic targets. We previously reported that a human...
Neil, Stuart J. D., Clapham, Paul R., Nibbs, Robert J., McKnight, Áine, Weiss, Robin A.
The role of coreceptors other than CCR5 and CXCR4 in the pathogenesis of human immunodeficiency virus (HIV) disease is controversial. Here we show that a promiscuous CC chemokine receptor, D6, can...
Marchant, David, Neil, Stuart J. D., Aubin, Keith, Schmitz, Christian, McKnight, Áine
We identified a postentry restriction, termed Lv2, which determines the cellular tropism of two related human immunodeficiency virus type 2 (HIV-2) isolates and is dependent on the sequence of the...
Neil, Stuart J. D, Eastman, Scott W, Jouvenet, Nolwenn, Bieniasz, Paul D
The human immunodeficiency virus (HIV) type-1 viral protein U (Vpu) protein enhances the release of diverse retroviruses from human, but not monkey, cells and is thought to do so by ablating a...
Plasma Membrane Is the Site of Productive HIV-1 Particle Assembly
Jouvenet, Nolwenn, Neil, Stuart J. D, Bess, Cameron, Johnson, Marc C, Virgen, Cesar A, Simon, Sanford M, ...
Recently proposed models that have gained wide acceptance posit that HIV-1 virion morphogenesis is initiated by targeting the major structural protein (Gag) to late endosomal membranes. Thereafter,...
McNatt, Matthew W., Zang, Trinity, Hatziioannou, Theodora, Bartlett, Mackenzie, Fofana, Ismael Ben, Johnson, Welkin E., ...
Tetherin/BST-2/CD317 is a recently identified antiviral protein that blocks the release of nascent retrovirus, and other virus, particles from infected cells. An HIV-1 accessory protein, Vpu, acts as...
Broad-Spectrum Inhibition of Retroviral and Filoviral Particle Release by Tetherin▿
Jouvenet, Nolwenn, Neil, Stuart J. D., Zhadina, Maria, Zang, Trinity, Kratovac, Zerina, Lee, Youngnam, ...
The expression of many putative antiviral genes is upregulated when cells encounter type I interferon (IFN), but the actual mechanisms by which many IFN-induced gene products inhibit virus...