Anatole Ghazalpour, Sudheer Doss, Xia Yang, Jason Aten, Edward M. Toomey, Atila Van Nas, ...
thematic review
Supplemental Material can be found at: (2008)
Anatole Ghazalpour, Sudheer Doss, Xia Yang, Jason Aten, Edward M. Toomey, Atila Van, ...
Key words: systems biology; transgenic mice; quantitative trait locus mapping; principal components; Bayesian networks; correlation coefficients; genetics; genomics; proteomics Correspondence:
Integrating Genetic and Network Analysis to Characterize Genes Related to Mouse Weight (2006)
Anatole Ghazalpour, Sudheer Doss, Bin Zhang, Susanna Wang, Christopher Plaisier, Ruth Castellanos, ...
Systems biology approaches that are based on the genetics of gene expression have been fruitful in identifying genetic regulatory loci related to complex traits. We use microarray and genetic marker...
Integrating Genetic and Network Analysis to Characterize Genes Related to Mouse Weight (2006)
Anatole Ghazalpour, Sudheer Doss, Bin Zhang, Susanna Wang, Christopher Plaisier, Ruth Castellanos, ...
Gene mapping approaches that are based on the genetics of gene expression have been fruitful in identifying genetic regulatory loci related to complex traits. Recently, several groups have proposed...
Genomic analysis of metabolic pathway gene expression in mice (2005)
Ghazalpour, Anatole, Doss, Sudheer, Sheth, Sonal S, Ingram-Drake, Leslie A, Schadt, Eric E, Lusis, Aldons J, ...
Abstract Background A segregating population of (C57BL/6J × DBA/2J)F2 intercross mice was studied for obesity-related traits and for global gene expression in liver. Quantitative trait locus...
Cis-acting expression quantitative trait loci in mice (2005)
Doss, Sudheer, Schadt, Eric E., Drake, Thomas A., Lusis, Aldons J.
We previously reported the analysis of genome-wide expression profiles and various diabetes-related traits in a segregating cross between inbred mouse strains C57BL/6J (B6) and DBA/2J (DBA). By...
Cis-acting expression quantitative trait loci in mice (2005)
Doss, Sudheer, Schadt, Eric E., Drake, Thomas A., Lusis, Aldons J.
We previously reported the analysis of genome-wide expression profiles and various diabetes-related traits in a segregating cross between inbred mouse strains C57BL/6J (B6) and DBA/2J (DBA). By...
Cis-acting expression quantitative trait loci in mice
Doss, Sudheer, Schadt, Eric E., Drake, Thomas A., Lusis, Aldons J.
We previously reported the analysis of genome-wide expression profiles and various diabetes-related traits in a segregating cross between inbred mouse strains C57BL/6J (B6) and DBA/2J (DBA). By...
Genomic analysis of metabolic pathway gene expression in mice
Ghazalpour, Anatole, Doss, Sudheer, Sheth, Sonal S, Ingram-Drake, Leslie A, Schadt, Eric E, Lusis, Aldons J, ...
In order to evaluate metabolic pathways associated with obesity, global gene-expression data were integrated with phenotypic and genetic segregation analyses, identifying 13 metabolic pathways the...
Integrating Genetic and Network Analysis to Characterize Genes Related to Mouse Weight
Ghazalpour, Anatole, Doss, Sudheer, Zhang, Bin, Wang, Susanna, Plaisier, Christopher, Castellanos, Ruth, ...
Systems biology approaches that are based on the genetics of gene expression have been fruitful in identifying genetic regulatory loci related to complex traits. We use microarray and genetic marker...
Cis-acting expression quantitative trait loci in mice
Doss, Sudheer, Schadt, Eric E., Drake, Thomas A., Lusis, Aldons J.
We previously reported the analysis of genome-wide expression profiles and various diabetes-related traits in a segregating cross between inbred mouse strains C57BL/6J (B6) and DBA/2J (DBA). By...
Genomic analysis of metabolic pathway gene expression in mice
Ghazalpour, Anatole, Doss, Sudheer, Sheth, Sonal S, Ingram-Drake, Leslie A, Schadt, Eric E, Lusis, Aldons J, ...
In order to evaluate metabolic pathways associated with obesity, global gene-expression data were integrated with phenotypic and genetic segregation analyses, identifying 13 metabolic pathways the...
Integrating Genetic and Network Analysis to Characterize Genes Related to Mouse Weight
Ghazalpour, Anatole, Doss, Sudheer, Zhang, Bin, Wang, Susanna, Plaisier, Christopher, Castellanos, Ruth, ...
Systems biology approaches that are based on the genetics of gene expression have been fruitful in identifying genetic regulatory loci related to complex traits. We use microarray and genetic marker...
High-Resolution Mapping of Gene Expression Using Association in an Outbred Mouse Stock
Ghazalpour, Anatole, Doss, Sudheer, Kang, Hyun, Farber, Charles, Wen, Ping-Zi, Brozell, Alec, ...
Quantitative trait locus (QTL) analysis is a powerful tool for mapping genes for complex traits in mice, but its utility is limited by poor resolution. A promising mapping approach is association...